𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Keowee from RM266 (2026) - Fully Refundable Options

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Our top choices for Keowee hotels

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.

An outdoor patio with wicker furniture, a round table, and a fountain.

1. The Shepherd Hotel Downtown Clemson

Clemson

Laurrie

RM854

RM948 total

includes taxes & fees

13 Oct - 14 Oct

An outdoor patio area with a fire pit, seating, and string lights.

A modern restaurant with a central counter, seating area, and a TV displaying news.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

2. Tru by Hilton Seneca Clemson

Seneca

Gretchen

RM432

RM475 total

includes taxes & fees

18 Oct - 19 Oct

A golf course with a water body, trees, and a distant view of a bridge.

An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

A golf course with a clubhouse, surrounded by dense trees and a large body of water.

3. Clemson University's James F. Martin Inn

Clemson

Lilllian

RM609

RM676 total

includes taxes & fees

6 Oct - 7 Oct

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

4. Lakeside Lodge Clemson

Seneca

Lori

RM431

RM536 total

includes taxes & fees

6 Oct - 7 Oct

A modern kitchen area with a bar counter and seating.

A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

A vending area with snacks and beverages, including chips and soda.

A modern bar area with high stools and a poolside view.

5. Hampton Inn Clemson-University Area

Clemson

Blaise

RM448

RM497 total

includes taxes & fees

12 Oct - 13 Oct

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.

A modern living room with a flat-screen TV, a desk with a chair, an orange sofa, and a framed tiger picture on the wall.

A conference room with a large round table, multiple chairs, and a projector.

6. Holiday Inn Express & Suites Clemson by IHG

Clemson

John

RM527

RM585 total

includes taxes & fees

11 Oct - 12 Oct

A modern bar area with a menu board, bar stools, and a countertop with various items.

An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

A modern dining area with a bar, bar stools, and a patterned rug.

7. Courtyard Marriott Clemson

Clemson

kim

RM529

RM588 total

includes taxes & fees

18 Oct - 19 Oct

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.

A lobby with seating areas, a reception desk, and a patterned wall.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

8. Best Western Plus Clemson Hotel & Conference Center

Clemson

David

RM431

RM478 total

includes taxes & fees

7 Oct - 8 Oct

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A hotel room with two beds, a desk, a television, and a clock on the wall.

A wall with a decorative design featuring a building, trees, and a sky with clouds.

A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

9. Inn @ Clemson

Clemson

Heather

RM327

RM363 total

includes taxes & fees

6 Oct - 7 Oct

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

A bar area with a counter, multiple chairs, and a display of bottles and glasses.

10. The Abernathy of Clemson

Clemson

Robert

RM658

RM730 total

includes taxes & fees

18 Oct - 19 Oct

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

A modern lobby with a reception desk, seating area, and a vending machine.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

11. Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

Angela

RM490

RM539 total

includes taxes & fees

11 Oct - 12 Oct

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A brick building with a sign reading "The Inn at Patrick Square".

A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".

A hotel lobby with a long corridor, seating areas, and a reception desk.

12. The Inn at Patrick Square

Clemson

Jennifer

RM609

RM676 total

includes taxes & fees

6 Oct - 7 Oct

A spacious room with a large window, a flat-screen TV mounted on the wall, and a seating area with sofas and chairs.

A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.

A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.

13. Comfort Inn & Suites Clemson - University Area

Clemson

Yvette

RM437

RM486 total

includes taxes & fees

18 Oct - 19 Oct

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

A gazebo with a tiled roof and a surrounding gravel area.

A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.

14. Days Inn by Wyndham Clemson

Clemson

"While my room was very clean, there was a large stain on the upholstered chair by the window. The picture was missing the bottom part of the frame. The bathroom was old, with a cigarette stain on the tub. Staff were friendly and helpful but it took longer than usual to check in. There was no pepper in the breakfast area and the juice machine was broken. All said and done, I had what I needed. It is a poor economy for all which may explain the shortcomings."

Cynthia

RM327

RM363 total

includes taxes & fees

6 Oct - 7 Oct

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

A reception area with a counter, chairs, and a patterned rug.

A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

15. Hampton Inn & Suites Seneca-Clemson Area

Seneca

Lloyd

RM485

RM533 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

16. Best Western Seneca-Clemson

Seneca

Michelle

RM382

RM420 total

includes taxes & fees

28 Oct - 29 Oct

A modern hotel room with a large bed, a desk with a chair, a small table, and a nightstand with a lamp.

A gym with exercise equipment, a mirror, and a blue wall.

A breakfast station with a toaster, a fruit bowl, and a bakery display.

A Holiday Inn Express & Suites hotel with a modern architectural design, featuring a prominent entrance with columns and a flat roof.

17. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

Dominique

RM449

RM499 total

includes taxes & fees

11 Oct - 12 Oct

A white, two-story house with a front porch, surrounded by trees and shrubs.

A bedroom with two beds, a TV, and a fireplace.

A dining area with round tables, black chairs, and white tablecloths.

A two-story building with a white exterior, a front door, and a balcony.

18. Liberty Hall Bed and Breakfast

Pendleton

Christine

RM466

RM517 total

includes taxes & fees

8 Oct - 9 Oct

A hotel lobby with a reception desk, seating area, and a view of the street outside.

A reception area with a desk, two chairs, a large water dispenser, and a painting on the wall.

A hotel room with a bed, desk, chair, nightstand, lamp, and a view of the outside through curtains.

A modern kitchen with wooden cabinets, a built-in dishwasher, a large window with a view of the outside, and a flat-screen TV mounted on the wall.

19. Econo Lodge Clemson - University Area

Clemson

Ruth

RM344

RM388 total

includes taxes & fees

25 Oct - 26 Oct

A modern bar area with a marble counter, houndstooth patterned chairs, and pendant lighting.

A modern bar area with a marble countertop, houndstooth patterned chairs, and pendant lighting.

A modern interior with round tables, houndstooth patterned chairs, a bar area, and a view through large windows.

A patio area with stone walls, outdoor furniture, and large windows.

20. Holiday Inn Anderson by IHG

Anderson

Deirdre

RM482

RM535 total

includes taxes & fees

2 Nov - 3 Nov

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Top Keowee Hotel Reviews

Days Inn by Wyndham Anderson

8/10 Good

"-"

The Abernathy of Clemson

10/10 Excellent

"You can’t beat the location and rooms are fabulous!"

Comfort Suites Anderson-Clemson

8/10 Good

"OK for night or two if you are catching a game in Clemson. Movie theater right across the road and couple of restaurants within close walking distance."

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"Very clean room with a great staff! Breakfast was excellent!"

Woodspring Suites Anderson North I-85

8/10 Good

"Everything was great only thing I would make note of is the shower curtain had mold on it."

Horizon Inn & Suites

10/10 Excellent

"The pretty lady at the front desk is absolutely fabulous."

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"It was a lovely from beginning to end. The staff is amazing."

Inn @ Clemson

10/10 Excellent

"Clean room close to Clemson"

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent

"Great place to stay when visiting Clemson!"

More cheap stays in Keowee

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC

RM240

RM266 total

11 Oct - 12 Oct

includes taxes & fees

8.2/10 Very good! (1,007 reviews)

Horizon Inn & Suites

3025 N Main Street Anderson SC

RM229

RM270 total

7 Oct - 8 Oct

includes taxes & fees

4.6/10 (365 reviews)

Quality Inn Seneca US-123

226 Hi Tech Rd Seneca SC

RM309

RM364 total

11 Oct - 12 Oct

includes taxes & fees

8/10 Very good! (755 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

RM431

RM478 total

7 Oct - 8 Oct

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

RM437

RM486 total

18 Oct - 19 Oct

includes taxes & fees

8.4/10 Very good! (1,007 reviews)

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

RM431

RM536 total

6 Oct - 7 Oct

includes taxes & fees

Frequently asked questions

What's the best place to stay in Keowee?

Located 3.1 mi (4.9 km) from the heart of Keowee, Best Western Plus Clemson Hotel & Conference Center is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Lakeside Lodge Clemson and Days Inn by Wyndham Anderson. See all available top hotels, or vacation rentals in Keowee.

If I need to cancel my hotel reservation in Keowee, will I receive a refund?

Yes, you'll find most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Keowee.

What is the top LGBTQ-friendly hotel in Keowee?

Tru by Hilton Seneca Clemson is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. See all available hotels listed as LGBTQ-friendly in Keowee.

What's the best dog-friendly hotel in Keowee?

Tru by Hilton Seneca Clemson is a top hotel for people travelling with their pets, and offers a fitness centre and laundry facilities for its human guests. See more pet-friendly hotel accommodations in Keowee.

What are some accommodation options with pools in Keowee?

Days Inn by Wyndham Anderson: Offers daily, a seasonal outdoor pool and free self parking. Best Western Plus Clemson Hotel & Conference Center and Quality Inn Seneca Clemson Area US-123 are a couple of other choices with an on-site pool. View all hotels with pools in Keowee.

How is it staying in Keowee?

Travellers to Keowee will find plenty to explore and enjoy. There are 1382 hotels and other accommodation options in the surrounding area. Find out more about Keowee.

What should I do while I'm visiting Keowee?

Places to visit in the wider area include Littlejohn Coliseum, Memorial Stadium and Fort Hill. You'll also find Walker Golf Course and Brooks Center for the Performing Arts in the area. Take a look at what more there is to see and do in Expedia's Keowee guide.

What's the seasonal weather in Keowee?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Keowee is 1561 mm.

Keowee hotels from RM266

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Keowee

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Keowee hotels

1. The Shepherd Hotel Downtown Clemson

2. Tru by Hilton Seneca Clemson

3. Clemson University's James F. Martin Inn

4. Lakeside Lodge Clemson

5. Hampton Inn Clemson-University Area

6. Holiday Inn Express & Suites Clemson by IHG

7. Courtyard Marriott Clemson

8. Best Western Plus Clemson Hotel & Conference Center

9. Inn @ Clemson

10. The Abernathy of Clemson

11. Fairfield Inn & Suites Seneca Clemson Univ Area

12. The Inn at Patrick Square

13. Comfort Inn & Suites Clemson - University Area

14. Days Inn by Wyndham Clemson

15. Hampton Inn & Suites Seneca-Clemson Area

16. Best Western Seneca-Clemson

17. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

18. Liberty Hall Bed and Breakfast

19. Econo Lodge Clemson - University Area

20. Holiday Inn Anderson by IHG

Top Keowee Hotel Reviews

Days Inn by Wyndham Anderson

The Abernathy of Clemson

Comfort Suites Anderson-Clemson

Comfort Inn & Suites Clemson - University Area

Woodspring Suites Anderson North I-85

Horizon Inn & Suites

The Shepherd Hotel Downtown Clemson

Inn @ Clemson

Hampton Inn & Suites Seneca-Clemson Area

More cheap stays in Keowee

Days Inn by Wyndham Anderson

Horizon Inn & Suites

Quality Inn Seneca US-123

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Frequently asked questions

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