Photo by Mark Rentz

Isla Santa María hotels from RM165

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Isla Santa María hotels

Hotel el descanso del Guia

3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (172)
"Beautiful and spacious family room. Good breakfast and the staff is courteous. I highly recommend this hotel. "
United States
Susanna
The price is RM265
RM265 total
1 Dec - 2 Dec
Hotel el descanso del Guia

Fernandina Hotel & Spa Galápagos

3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (22)
"Lovely staff and great location "
United States
Lucas
The price is RM620
RM620 total
15 Dec - 16 Dec
Fernandina Hotel & Spa Galápagos

Hotel Fiesta

3.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (377)
"Friendly helpful staff, great location close to waterfront shops and restaurants. Nicely maintained landscape "
United States
Michael
The price is RM642
RM642 total
20 Dec - 21 Dec
Hotel Fiesta

Hotel Ninfa

3.5 star property
Puerto Ayora
8.4 out of 10, Very good, (216)
"Everything is in walking distance, great price , the rooms were clean comfortable and had AC , the staff was fantastic and the breakfast had many option. Would certainly recommend "
United States
randi
Hotel Ninfa

Galapagos Dreams

3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (123)
"We stayed for 4 days was very good, the breakfast was delicious and also we booked the activities with them, everything was excellent "
United States
esperanza
The price is RM266
RM293 total
1 Dec - 2 Dec
Galapagos Dreams

Hotel La Isla

3.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (63)
"We are so happy we chose to stay here while on the island. Great location, staff, and property! "
United States
Anonymous traveller
Hotel La Isla

Angermeyer Waterfront Inn

3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (124)
"Beautiful view and very friendly staff. You do have to take a water taxi ($1 and operates 24/7) to the main part of downtown Santa Cruz but the view is worth it! Also it’s across from The Point by Midoro which as an amazing view and food. I would stay there again! "
United States
Ahram
The price is RM970
RM1,067 total
1 Dec - 2 Dec
Angermeyer Waterfront Inn

Posada del Mar

3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (210)
"Well maintained property, front staff was very kind and helpful, and the restaurants beside it were incredible."
Canada
Bianca
The price is RM309
RM309 total
1 Dec - 2 Dec
Posada del Mar

Twin Hotel Galapagos

3.0 star property
Bella Vista
8.4 out of 10, Very good, (44)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
Canada
Chelsea
The price is RM354
RM354 total
1 Dec - 2 Dec
Twin Hotel Galapagos

Hotel Cucuve

4.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (267)
"Very nice location, friendly staff "
Italy
davide
The price is RM992
RM1,091 total
17 Dec - 18 Dec
Hotel Cucuve

Galapagos Chalet

2.5 star property
Puerto Ayora
4.0 out of 10, (1)
"After we finally got checked in, turned the AC on and it was not cold. Owner told me it would cool down and to let her know if I didn't need it "cold like hers (friend's room) I would be fine but I could switch it in the morning. Let me be clear, the AC did not work AT ALL and when we returned it was hotter in the room than outside at 9pm. Couldn't open the windows or doors because the of the mosquitoes. The owner was not on site, so I ended up having to share the room with my friend instead of...
United States
Anonymous traveller
Galapagos Chalet

White House Galapagos

2.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (99)
"."
Germany
Andrea Christine
White House Galapagos

Hotel Coloma Galapagos

3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (187)
"Hotel Coloma is in the Main Street with easy access to shops and Pier. Staff were friendly and the breakfast, fresh and delicious with your choice of eggs whatever way you want them. We needed 1 night prior to cruise departing - this was perfect. "
Australia
Russell
Hotel Coloma Galapagos

Hotel La Casa de Judy

3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (159)
"The staff was nice and friendly. They were accommodating to our needs. They offered helpful suggestions to places and food locations nearby. Recommend coming here again."
United States
Marcela Estefania Pasquel De La
Hotel La Casa de Judy

Hotel Santa Fe

4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (14)
"Beautiful hotel, with amazing staff, and great location "
United States
Steven
The price is RM766
RM843 total
1 Dec - 2 Dec
Hotel Santa Fe

Maidith Galapagos Inn

3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (100)
"Great beautiful accommodation, very clean, big rooms, near city center but also quiet. The owners couple is really great and helpful in anything. "
Netherlands
A.
The price is RM521
RM521 total
5 Dec - 6 Dec
Maidith Galapagos Inn

Hostal Sir Francis Drake

2.5 star property
Puerto Ayora
7.4 out of 10, Good, (73)
"Great location!"
United States
John
The price is RM289
RM289 total
8 Dec - 9 Dec
Hostal Sir Francis Drake

Hostal North Seymour

3.0 star property
Puerto Ayora
8.6 out of 10, Excellent, (143)
"Great place to stay. Staff are very friendly and helpful."
United States
Michael
Hostal North Seymour

Plaza Luna Suites

3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (33)
"This hotel great location and employees are awesome, wonderful, nice and very professional friendly. This hotel is a gem in Puerto Ayora "
United States
Jorge A.
Plaza Luna Suites

Casa del Lago Lodging House

2.0 star property
Puerto Ayora
7.8 out of 10, Good, (13)
"The Tortuga bay suite is right by the street so you hear the street noise until about 10:30pm on workdays and about 11:30pm on a Friday. The air conditioner doesn’t work well. It makes a noise at night and is quite disturbing. With the many mosquitoes, we could not open the windows and it was quite a terrible experience to sleep at night. The soap and shampoo/body wash are diluted. The fridge is incredibly noisy and you cannot sleep with it being on. The plates are dirty and require extra...
United States
Jingyuan
The price is RM227
RM254 total
29 Dec - 30 Dec
Casa del Lago Lodging House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Isla Santa María attractions

Learn more about Isla Santa María

Explore attractions like Galápagos National Park and Post Office Bay as you discover things to see and do in Isla Santa María.

A greater flamingo searching for dinner. There were a few hundred of them wading in the lagoon.
Photo by Mark Rentz
Open Photo by Mark Rentz

Top Isla Santa María Hotel Reviews

More cheap stays in Isla Santa María

Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are El Barranco Galapagos and Hotel el descanso del Guia. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best holiday rentals that Isla Santa María has to offer?
Villa Galapagos: This holiday home rental outside of Isla Santa María is located near the beach, and offers a private garden, air conditioning and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
What is staying in Isla Santa María like?
Travellers to Isla Santa María will find plenty to explore and enjoy. There are 208 hotels and other accommodation options in the larger region. Find out more about Isla Santa María.
What is there to see in Isla Santa María?
Favourite places to visit include Galápagos National Park, Post Office Bay and Punta Suarez. Take a look at what more there is to see and do in Expedia's Isla Santa María guide.
What's the seasonal weather in Isla Santa María?
The hottest months are usually March and February, with an average temperature of 26°C, while the coldest months are September and October, with an average of 22°C. Average annual precipitation for Isla Santa María is 319 mm.