10 Best Business Hotels in Florida Keys for 2026

A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Florida Keys Business Hotels

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Florida Keys business-friendly hotels

1. Havana Cabana at Key West

New Town

Silvia

RM447

RM760 total

includes taxes & fees

27 Sept - 28 Sept

2. DoubleTree Resort by Hilton Grand Key - Key West

Key West

Jose

RM420

RM609 total

includes taxes & fees

27 Sept - 28 Sept

3. Hampton Inn Key West FL

Key West

Melisa

RM480

RM540 total

includes taxes & fees

15 Sept - 16 Sept

4. Hilton Key West Resort & Marina

Stock Island

Elizabeth

RM430

RM726 total

includes taxes & fees

20 Sept - 21 Sept

5. Beachside Resort & Residences

Key West

Jerome

RM367

RM802 total

includes taxes & fees

13 Sept - 14 Sept

6. Parrot Key Hotel & Villas

Northside Resort

Anthony

RM524

RM823 total

includes taxes & fees

22 Sept - 23 Sept

7. Lime Tree Bay Resort

Long Key

Chadwick

RM423

RM821 total

includes taxes & fees

20 Sept - 21 Sept

8. Ocean Key Resort - A Noble House Resort

Key West Historic District

Brian

RM895

RM1,322 total

includes taxes & fees

28 Sept - 29 Sept

View all properties

Top Florida Keys Hotel Reviews

The Pelican Key Largo Cottages

10/10 Excellent

"This is my new go-to place to stay in Key Largo! It's clean, quaint & a good location. The view at the dock at Sunset was stunning. We had two queens & a bathroom. Our room was right behind the check in building so it was convenient to us. There also seems to be a table & chairs outside each room, I didn't know that when I booked but I was able to have my morning tea outside. Another nice feature was the in-room fridge (which was super cold), the coffee maker & the microwave. This microwave was nice! It had a USB & 3-prong plug on the front of it & when it stops running it's locked & you have to push the unlock button. If you are traveling with kids, this is a wonderful safety feature! We walked down to the docks twice on our overnight stay. There are chairs on the beach & on the dock. There were plenty of local places to eat, but I recommend C&Cs Wood Fired Pizza for their happy hour from 4-6 pm. A pizza (6 slices) & a pitcher for $10! At the Cottages, the staff were super nice. Irina & the other lady at check in were so helpful. I even asked a grounds person a question & he was helpful too. I don't care about super fancy. I care about CLEAN, a great view & beautiful surrounding. It's all of this & more!"

Islander Resort

8/10 Good

"Good location. nice clean rooms. bed was very firm. pool tends to get very warm."

Amara Cay Resort

10/10 Excellent

"I like Everything!"

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent

"Espectacular 🤗✨🤩 sigue siendo mi preferido"

Frequently asked questions

How much do business-friendly hotels in Florida Keys cost?

Prices for business hotels in Florida Keys range between RM540 and RM1,322 per night. No matter your budget, Expedia can help you locate the ideal space to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Florida Keys?

Florida Keys has multiple business-friendly hotels with a total average guest review rating of 9.0. Attending a work-related event in Key West? The Perry Hotel & Marina Key West is a 4-stars stay that comes highly recommended by corporate travellers and includes a nearby waterfront and a garden. Another excellent pick for an official business trip is Silver Palms Inn. Also in Key West, it has a 3.5-stars rating and conveniences such as an electric car charging station and a swimming pool.

How many business-friendly hotels are there in Florida Keys?

Florida Keys has 87 business-friendly hotels to pick from. Whether you're attending a conference or meeting or working remotely, these stays are equipped with the amenities you need to be productive.

What are the best cheap business-friendly hotels in Florida Keys?

That depends on which part of Florida Keys your working visit is taking you. If you're travelling to Key West, Best Western Hibiscus Motel meets the needs of business travellers at an affordable price. A spa tub and a restaurant are among its many conveniences. Meeting with clients in Key Largo? Check in to Coconut Palm Inn. Pool sun loungers and a garden help make this inexpensive property a favourite with corporate guests. Business-friendly hotels start from just RM540 a night, so your work trip doesn't have to be costly. Want to explore Florida Keys without blowing your budget? Take a break from your business events to visit cool free attractions like Smathers Beach in Key West. Key Largo also has plenty of things to do that won't cost a penny, including Baker's Cay Resort Beach. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in Florida Keys that are also business friendly?

If you're travelling for business in Florida Keys and bringing your family along with you, Expedia will help you find a suitable stay. Eden House in Key West is an ideal option for those juggling work and pleasure. This 3.5-stars property offers all the necessary amenities, like a sauna and a cafe. Hyatt Centric Key West Resort and Spa is another good choice in Key West. Combine corporate travel and quality time with your family at this 4-stars property. A nearby beach and WiFi are two of the many conveniences you'll find here. There are plenty of terrific things to do for the whole family in Key West. Smathers Beach and South Beach promise a great day out.

Are there any 5-star business-friendly hotels in Florida Keys?

While there aren't any 5-star business-friendly hotels in Florida Keys, there are still chic properties to choose from. Work taking you to Key West? The Perry Hotel & Marina Key West is a popular option that has everything you need while you're away from home on business. Amenities at this 4-star property include pillow top mattresses and designer toiletries. Ocean Key Resort - A Noble House Resort is another recommendation that caters to corporate travellers in Key West. Also rated 4 stars and featuring a swimming pool and a resort, you'll find plenty to love about this hotel.

Why book your business-friendly hotel in Florida Keys with Expedia?

Here at Expedia, our top task is to help you land a suitable stay at the right price. From deluxe, corporate-friendly getaways to affordable motels filled with all the amenities you need, you'll have your next work trip planned in a few quick clicks.

How can I find cheap business-friendly hotels in Florida Keys?

When work takes you on the road in Florida Keys, our "business friendly" filter will help you find the ideal hotel. From included breakfast and free WiFi to concierge services and conference spaces, they come with the amenities you need to be productive. You can also refine your search by your budget and preferred star rating to see the cheapest properties.

What is there to do in Florida Keys near my business-friendly hotel?

Whether you like shopping, dining, history or culture, Florida Keys is one place you'll never get bored! The well-known city of Key West has tons of attractions, including Smathers Beach, South Beach and Clarence S. Higgs Memorial Beach Park. If you're planning a work trip to Key Largo, Baker's Cay Resort Beach, Jimmy Johnson's Big Chill and Bluefin Rock Harbour Marina are worth putting on your itinerary.

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Florida Keys Business Hotels

Our top choices for Florida Keys business-friendly hotels

1. Havana Cabana at Key West

2. DoubleTree Resort by Hilton Grand Key - Key West

3. Hampton Inn Key West FL

4. Hilton Key West Resort & Marina

5. Beachside Resort & Residences

6. Parrot Key Hotel & Villas

7. Lime Tree Bay Resort

8. Ocean Key Resort - A Noble House Resort

9. Cheeca Lodge & Spa

10. Blue Flamingo Resort Key West

Top Florida Keys Hotel Reviews

The Pelican Key Largo Cottages

Islander Resort

Amara Cay Resort

Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

Explore a world of travel with Expedia