Hotels in Downtown South San Francisco, San Francisco

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21 Dec - 22 Dec
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22 Dec - 23 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Downtown South San Francisco hotels

Fridge, microwave, coffee/tea maker, dining tables
Miller Apartments

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (15)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is RM245
RM595 total
includes taxes & fees
23 Dec - 24 Dec
Miller Apartments
Exterior
La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (2006)
"Clean room, staff were friendly, breakfast was good, parking was good, overall we're satisfied!"
Canada
Edna
The price is RM412
RM484 total
includes taxes & fees
1 Jan - 2 Jan 2026
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Interior detail
Airport Inn

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (972)
"Very clean room, friendly staff and secure parking."
United States
Christopher
The price is RM404
RM473 total
includes taxes & fees
22 Dec - 23 Dec
Airport Inn
Lobby
Inn By The SFO

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1000)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
United States
David
Inn By The SFO
Restaurant
Inn at Rockaway San Francisco Pacifica

Inn at Rockaway San Francisco Pacifica

Inn at Rockaway San Francisco Pacifica
2.5 star property
8.8 km from Downtown South San Francisco
8.2 out of 10, Very good, (1003)
"Pleased with our 4 night stay here. The rooms have been upgraded and are clean and well appointed. The staff was pleasant and helpful. We loved the town and the area around the hotel has food and shops within walking distance. Would stay again. "
United States
Stacy
Inn at Rockaway San Francisco Pacifica
Premium bedding, down duvets, in-room safe, desk
Harbor View Inn

Harbor View Inn

Harbor View Inn
2.0 star property
17.7 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (623)
"very clean, very friendly, close to fun areas"
United States
michael
The price is RM447
RM563 total
includes taxes & fees
28 Dec - 29 Dec
Harbor View Inn
Property entrance
Menlo Park Inn

Menlo Park Inn

Menlo Park Inn
3.0 star property
30.2 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1000)
"We've stayed here a few times and have always been happy with our choice. Friendly owners, good breakfast"
United States
Evan
Menlo Park Inn
Outdoor pool
The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
20.6 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2295)
"Clean, cozy, great staff!"
United States
Stacie
The Marina Inn on San Francisco Bay
Exterior
Half Moon Bay Lodge

Half Moon Bay Lodge

Half Moon Bay Lodge
3.0 star property
24.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1084)
"Always great staff here, nice rooms, nice jacuzzi "
United States
Pamela
The price is RM479
RM563 total
includes taxes & fees
12 Jan - 13 Jan 2026
Half Moon Bay Lodge
Exterior
The Westin San Francisco Airport

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
6.8 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2025)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is RM420
RM602 total
includes taxes & fees
23 Dec - 24 Dec
The Westin San Francisco Airport
Exterior
Aloft San Francisco Airport

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
6.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2240)
"All good, friendly staff, spotless room. "
United States
Michael
The price is RM409
RM470 total
includes taxes & fees
29 Dec - 30 Dec
Aloft San Francisco Airport
Free daily continental breakfast
La Quinta Inn & Suites by Wyndham Oakland - Hayward

La Quinta Inn & Suites by Wyndham Oakland - Hayward

La Quinta Inn & Suites by Wyndham Oakland - Hayward
3.0 star property
26.3 km from Downtown South San Francisco
8.4 out of 10, Very good, (1095)
"Polite staff; clean and comfortable room"
United States
Cindi
The price is RM362
RM414 total
includes taxes & fees
18 Jan - 19 Jan 2026
La Quinta Inn & Suites by Wyndham Oakland - Hayward
Exterior
Stanyan Park Hotel

Stanyan Park Hotel

Stanyan Park Hotel
3.0 star property
12.8 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1003)
"It was my second stay and Stanyan Park, and it's my favorite place to stay in San Francisco, by far. Wonderful room, wonderful hotel, wonderful location."
United States
Sean
The price is RM797
RM927 total
includes taxes & fees
4 Jan - 5 Jan 2026
Stanyan Park Hotel
Bar (on property)
Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side, 1.3 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1238)
"Everything was just great the amenities the staff the cleanliness the breakfast I had a very relaxing and great time "
United States
Lily
The price is RM598
RM702 total
includes taxes & fees
27 Dec - 28 Dec
Embassy Suites by Hilton San Francisco Airport Oyster Point
Desk, blackout curtains, iron/ironing board, free WiFi
Hotel Nova SFO

Hotel Nova SFO

Hotel Nova SFO
2.5 star property
1.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1000)
"Great hospitality staff is awesome will definitely stay here again !!"
United States
Cindy
The price is RM385
RM452 total
includes taxes & fees
26 Dec - 27 Dec
Hotel Nova SFO
Balcony view
Executive Inn & Suites Embarcadero Cove

Executive Inn & Suites Embarcadero Cove

Executive Inn & Suites Embarcadero Cove
3.0 star property
20.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1006)
"Staff was extremely nice and helpful "
United States
James
The price is RM516
RM600 total
includes taxes & fees
28 Dec - 29 Dec
Executive Inn & Suites Embarcadero Cove
Lobby
Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport
2.5 star property
11.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1250)
"Good place to stay, clean and good breakfast."
United States
Xiaohong
The price is RM395
RM454 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Inn & Suites San Mateo - San Francisco Airport
Exterior
SFO El Rancho Inn SureStay Collection by Best Western

SFO El Rancho Inn SureStay Collection by Best Western

SFO El Rancho Inn SureStay Collection by Best Western
3.0 star property
5.7 km from Downtown South San Francisco
8.4 out of 10, Very good, (2963)
"Rooms were very clean and the check in and check out was very quick. "
United States
Jacobo
The price is RM391
RM453 total
includes taxes & fees
27 Dec - 28 Dec
SFO El Rancho Inn SureStay Collection by Best Western
Lobby sitting area
The Dylan at SFO

The Dylan at SFO

The Dylan at SFO
3.0 star property
7.1 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1844)
"Great hotel and location for early morning flight. Very friendly staff, nice room. Would stay again. "
United States
Pierre
The price is RM442
RM526 total
includes taxes & fees
23 Dec - 24 Dec
The Dylan at SFO
Lobby
Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point, 2.2 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1904)
"always a great stay"
United States
Marco
The price is RM404
RM482 total
includes taxes & fees
28 Dec - 29 Dec
Sonesta Select San Francisco Airport Oyster Point Waterfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.
Union Square featuring a skyscraper and a city

Union Square

Packed with a treasure trove of upmarket boutiques, designer labels and department store, shoppers will love this huge shopping plaza.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman\'s Wharf featuring a bay or harbor

Fisherman's Wharf

This waterfront location is steeped in history dating back to the days of the gold rush. Today, visitors come here for its vibrant atmosphere and great food.

South of Market which includes skyline, a garden and a city

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing street scenes and a city

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

10/10 Excellent
"We had a great experience at the Chancellor hotel! Booked the room last minute at a great price - staff was very nice, room was small but clean, bathroom was a good size, and love that they have a water refill station in the lobby. Would stay again!"
Kaitlyn 1-night trip
Posted 15 hours ago
Chancellor Hotel on Union Square

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favourite options in the area include Airport Inn and Inn By The SFO.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
See's Candies, Cinemark Century at Tanforan and K1 Speed are just a few of the places to visit in and around Downtown South San Francisco. K1 Speed San Francisco and The Shops at Tanforan are also worth a visit when you're out sightseeing in South San Francisco.

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