South America Flights - Book Cheap Flights to South America

View RM724 flight on Wed, 11 Mar 2026Opens in a new window

Popular airlines to South America

  • Avianca

    Avianca

  • LATAM Airlines Group

    LATAM Airlines Group

  • American Airlines

    American Airlines

  • United

    United

  • Copa

    Copa

  • Delta

    Delta

  • Air Canada

    Air Canada

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Cheap round-trip flights to South America

Prices were available within the past 7 days and start at RM724 for one-way flights and RM1,969 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, 11 Mar - Sun, 15 Mar
MEX
Mexico City
BOG
Bogotá
RM1,969 Return, found 5 days ago
RM1,969
Return
found 5 days ago
Select Copa flight, departing Wed, 11 Mar from Mexico City to Bogotá, returning Sun, 15 Mar, priced at RM1,969 found 5 days ago
avianca
Wed, 11 Mar - Sun, 15 Mar
MEX
Mexico City
BOG
Bogotá
RM2,090 Return, found 5 days ago
RM2,090
Return
found 5 days ago
Select avianca flight, departing Wed, 11 Mar from Mexico City to Bogotá, returning Sun, 15 Mar, priced at RM2,090 found 5 days ago
Copa
Tue, 3 Feb - Wed, 18 Feb
MEX
Mexico City
LIM
Lima
RM2,116 Return, found 3 days ago
RM2,116
Return
found 3 days ago
Select Copa flight, departing Tue, 3 Feb from Mexico City to Lima, returning Wed, 18 Feb, priced at RM2,116 found 3 days ago
Copa
Sat, 31 Jan - Sun, 1 Feb
MEX
Mexico City
UIO
Quito
RM2,352 Return, found 2 days ago
RM2,352
Return
found 2 days ago
Select Copa flight, departing Sat, 31 Jan from Mexico City to Quito, returning Sun, 1 Feb, priced at RM2,352 found 2 days ago
Copa
Fri, 16 Jan - Fri, 23 Jan
MEX
Mexico City
GRU
Sao Paulo
RM2,728 Return, found 5 days ago
RM2,728
Return
found 5 days ago
Select Copa flight, departing Fri, 16 Jan from Mexico City to Sao Paulo, returning Fri, 23 Jan, priced at RM2,728 found 5 days ago
Arajet
Wed, 18 Mar - Wed, 27 May
NLU
Mexico City
EZE
Buenos Aires
RM2,898 Return, found 6 days ago
RM2,898
Return
found 6 days ago
Select Arajet flight, departing Wed, 18 Mar from Mexico City to Buenos Aires, returning Wed, 27 May, priced at RM2,898 found 6 days ago
Aeromexico
Tue, 27 Oct - Wed, 4 Nov
MEX
Mexico City
SCL
Santiago
RM3,035 Return, found 20 hours ago
RM3,035
Return
found 20 hours ago
Select Aeromexico flight, departing Tue, 27 Oct from Mexico City to Santiago, returning Wed, 4 Nov, priced at RM3,035 found 20 hours ago
GOL Linhas Aereas S.A.
Fri, 16 Jan - Fri, 23 Jan
MEX
Mexico City
GRU
Sao Paulo
RM3,165 Return, found 5 days ago
RM3,165
Return
found 5 days ago
Select GOL Linhas Aereas S.A. flight, departing Fri, 16 Jan from Mexico City to Sao Paulo, returning Fri, 23 Jan, priced at RM3,165 found 5 days ago
avianca
Wed, 18 Mar - Wed, 27 May
MEX
Mexico City
EZE
Buenos Aires
RM4,266 Return, found 6 days ago
RM4,266
Return
found 6 days ago
Select avianca flight, departing Wed, 18 Mar from Mexico City to Buenos Aires, returning Wed, 27 May, priced at RM4,266 found 6 days ago
American Airlines
Wed, 18 Mar - Wed, 27 May
MEX
Mexico City
EZE
Buenos Aires
RM4,846 Return, found 6 days ago
RM4,846
Return
found 6 days ago
Select American Airlines flight, departing Wed, 18 Mar from Mexico City to Buenos Aires, returning Wed, 27 May, priced at RM4,846 found 6 days ago

About South America

Expedia offers flights to South America to meet every traveler's needs. Whatever your flight need - Expedia has the flight for you. So choose from flights to South America or destinations around the world and discover how easy it is to make your flight reservations on Expedia.

Frequently asked questions

Can I cancel my flight booking to South America due to COVID-19?
If you haven't booked yet, look through the terms and conditions of the airline you're considering. If you've already reserved your flight to South America, visit our Customer Service Portal. The information here will help determine which COVID-19 policies are applicable to your reservation and advise the next steps.
What's the best way to find cheap flights to South America that have flexible change policies?
When it comes to flying these days, flexibility is important. That's why we have a "No change fee" search function to help you track down flexible and cheap tickets to South America. It's on the left of your screen underneath the "Flexible change policies" subheading.
What are some of the general tips for travelers to South America during the COVID-19 outbreak?
The COVID-19 pandemic has changed how we travel, but it hasn't shut down our desire to explore. Here are some tips on how to cope with travel's new challenges:

  • Find out the rules and restrictions in both your destination and origin. It may not be possible to travel depending on local circumstances, so check before you lock something in.
  • You're required to wear a face mask at the airport, including at security checkpoints. Be ready to lower your mask for ID purposes when asked by a TSA employee.
  • Rather than handing a TSA officer your boarding pass, position it straight on the scanner yourself. After that, hold it up for inspection.
  • One liquid hand sanitizer container is now permitted in your carry-on baggage. It must be no bigger than 12 oz (350 ml), and you'll need to take it out of your bag for X-ray scanning.
  • Place any personal items (phone, wallet and keys) in your carry-on rather than a bin to reduce handling during the screening process.
  • If you're taking food on the plane with you, place it in a clear plastic bag and then into a scanning bin. This lessens the likelihood that a TSA employee will need to touch your carry-on bag or food container for inspection.

How can I find cheap tickets to South America?
You'll always nab an unbeatable deal with Expedia, but our "flexible dates" feature makes it that much easier. Enter your preferred travel date, then click on the flexible dates link above to see a list of prices for nearby days. RM1,969 was the cheapest price for a flight to South America in the last seven days.
How much is a flight to South America?
The cost of a round-trip ticket to South America in the last seven days ranged between RM1,969 and RM5,240. If you were flying one way from Mexico City (NLU), you could have gotten a cheap seat from only RM724.
How much is a plane ticket to South America?
In the last seven days, airfares to South America cost between RM1,969 and RM5,240. Prices depend on multiple things, particularly the time of departure, cabin class, airline and when the fare is booked.
What are the best things to do in South America?

  • Kick off your South America vacation in the lively city of Sao Paulo. There's loads to keep you amused here, from top attractions like Paulista Museum to wonderful food, shopping, arts and more.
  • Sao Paulo is known for its humid subtropical climate. But before you jet off, check out what the weather will be doing while you're there. Hot, cold, wet or dry, it's always wise to arrive prepared.
  • Be sure to make Campinas the next place you go to. It's 80 kilometers to the northwest of Sao Paulo and where you'll find Museum of History and Porcelain of Pedreira, one of this destination's best tourist sights.

What months are the cheapest to book a flight to South America?
A great month to book well-priced flights to South America is February. Keep in mind that in the USA, an expensive time to secure a seat is during the festive month of December.

Trending flights to South America

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Cathay Pacific
Mon, 26 Jan - Mon, 2 Feb
KUL
Kuala Lumpur
SCL
Santiago
RM5,240 Return, found 2 hours ago
RM5,240
Return
found 2 hours ago
Select Cathay Pacific flight, departing Mon, 26 Jan from Kuala Lumpur to Santiago, returning Mon, 2 Feb, priced at RM5,240 found 2 hours ago
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