A large rock formation on a beach at sunset.

Hotels near Cape Romain National Wildlife Refuge

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Cape Romain National Wildlife Refuge hotels

A hotel with multiple swimming pools, outdoor seating areas, and a large building with balconies.

1. Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
4.0 star property
33.2 km from Cape Romain National Wildlife Refuge
8.8 out of 10, Excellent, (1,000 reviews)
"The staff was very gracious, the amenities were most enjoyable."
United States
Rebecca
The price is RM583
RM790 total
includes taxes & fees
6 Dec - 7 Dec
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
A modern bar area with a wooden ceiling, bar stools, and a counter.

2. Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
3.0 star property
39.9 km from Cape Romain National Wildlife Refuge
9.4 out of 10, Exceptional, (2,429 reviews)
"Great place to stay!"
United States
william
The price is RM423
RM483 total
includes taxes & fees
23 Nov - 24 Nov
Cambria Hotel Mount Pleasant – Charleston
A hotel lobby with seating areas, a reception desk, and decorative lighting.

3. Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston
2.5 star property
39.4 km from Cape Romain National Wildlife Refuge
9.2 out of 10, Wonderful, (1,487 reviews)
"Great visit"
United States
Angela
The price is RM343
RM395 total
includes taxes & fees
29 Nov - 30 Nov
Tru by Hilton Mt Pleasant Charleston
A modern hotel room with a bed, bedside tables, a desk, and a balcony with a view.

4. The Palms Oceanfront Hotel

The Palms Oceanfront Hotel
3.5 star property
37.8 km from Cape Romain National Wildlife Refuge
8.2 out of 10, Very good, (1,106 reviews)
"Centrally located in Isle of Palms, SC; the staff helpful, the room was clean and the beach was wide right outside the motel. Will stay there again."
United States
Troy O
The price is RM426
RM494 total
includes taxes & fees
29 Nov - 30 Nov
The Palms Oceanfront Hotel
A hotel lobby with reception desks, seating areas, and a wooden ceiling.

5. Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
2.5 star property
36.7 km from Cape Romain National Wildlife Refuge
8.8 out of 10, Excellent, (1,002 reviews)
"The staff was GREAT-Ashley at the desk was wonderful, you should be Proud to have her on your staff"
United States
Jesse
The price is RM402
RM454 total
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
A spacious lobby with high ceilings, large windows, and elegant furniture.

6. Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant
3.0 star property
39.5 km from Cape Romain National Wildlife Refuge
8.8 out of 10, Excellent, (1,002 reviews)
"Great stay. Comfortable room."
United States
Cynthia
The price is RM385
RM435 total
includes taxes & fees
13 Dec - 14 Dec
Courtyard by Marriott Charleston Mount Pleasant
A bar area with a curved counter, multiple seating options including round tables and chairs, and a patterned floor.

7. DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant
4.0 star property
40.6 km from Cape Romain National Wildlife Refuge
9.0 out of 10, Wonderful, (1,003 reviews)
"This is a beautiful property. Breakfast is amazing."
United States
Brandon
The price is RM367
RM424 total
includes taxes & fees
10 Dec - 11 Dec
DoubleTree by Hilton Charleston Mount Pleasant
A spacious dining area with multiple tables and chairs, large windows, and potted plants.

8. Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
2.5 star property
37.4 km from Cape Romain National Wildlife Refuge
9.0 out of 10, Wonderful, (1,001 reviews)
"Good location and value"
United States
Erik
The price is RM397
RM458 total
includes taxes & fees
13 Dec - 14 Dec
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
A modern living room with a sectional sofa, a flat-screen TV, and a small coffee table.

9. Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant
3.5 star property
39.7 km from Cape Romain National Wildlife Refuge
9.2 out of 10, Wonderful, (1,001 reviews)
"Clean room, comfortable bed, good breakfast."
United States
Melinda
The price is RM451
RM519 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt House Charleston / Mount Pleasant
A hotel room with a kitchenette, a bed, a desk, and a dining area.

10. TownePlace Suites Charleston Mt. Pleasant

TownePlace Suites Charleston Mt. Pleasant
3.0 star property
40.6 km from Cape Romain National Wildlife Refuge
9.0 out of 10, Wonderful, (583 reviews)
"Off the beaten path and quiet"
United States
Brett
The price is RM426
RM481 total
includes taxes & fees
22 Nov - 23 Nov
TownePlace Suites Charleston Mt. Pleasant
A beachfront hotel with a pool, beach access, and a sunset view.

11. Wild Dunes Resort – Residences at Sweetgrass

Wild Dunes Resort – Residences at Sweetgrass
3.5 star property
33.2 km from Cape Romain National Wildlife Refuge
8.6 out of 10, Excellent, (225 reviews)
"Great place that has everything on site to enjoy a great beach vacation."
United States
Jeff
The price is RM590
RM798 total
includes taxes & fees
6 Dec - 7 Dec
Wild Dunes Resort – Residences at Sweetgrass
A corridor with a view of the sunset over the ocean, palm trees, and a balcony with a railing.

12. Seaside Inn Oceanfront

Seaside Inn Oceanfront
2.5 star property
38 km from Cape Romain National Wildlife Refuge
7.8 out of 10, Good, (1,001 reviews)
"this hotel is incredible! perfect location, beachfront, great restaurants, lots of things to do. very clean and amazing staff!"
United States
Amanda
The price is RM400
RM465 total
includes taxes & fees
15 Nov - 16 Nov
Seaside Inn Oceanfront
A hotel lobby with a wooden reception desk, two chairs, large windows with a view of trees and a white fence, and a patterned carpet.

13. Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant
3.0 star property
37.2 km from Cape Romain National Wildlife Refuge
8.6 out of 10, Excellent, (1,002 reviews)
"Great stay"
United States
Melanie
The price is RM464
RM532 total
includes taxes & fees
30 Nov - 1 Dec
Homewood Suites by Hilton Charleston - Mt Pleasant
A hotel room with a blue sofa, two brown ottomans, a bed with white linens, and three framed pictures on the wall.

14. Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector
2.5 star property
37.4 km from Cape Romain National Wildlife Refuge
8.0 out of 10, Very good, (1,000 reviews)
"Marcia at the reception was exceptionally helpful and friendly!"
United States
Corey
The price is RM337
RM400 total
includes taxes & fees
6 Dec - 7 Dec
Comfort Suites at Isle Of Palms Connector
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Cape Romain National Wildlife Refuge

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A hotel with multiple swimming pools, outdoor seating areas, and a large building with balconies.
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
4.0 star property
8.8
Excellent
1,000 reviews
View
A modern bar area with a wooden ceiling, bar stools, and a counter.
Cambria Hotel Mount Pleasant – Charleston
3.0 star property
9.4
Exceptional
2,429 reviews
View
A hotel lobby with seating areas, a reception desk, and decorative lighting.
Tru by Hilton Mt Pleasant Charleston
2.5 star property
9.2
Wonderful
1,487 reviews
View
A modern hotel room with a bed, bedside tables, a desk, and a balcony with a view.
The Palms Oceanfront Hotel
3.5 star property
8.2
Very good
1,106 reviews
View
A hotel lobby with reception desks, seating areas, and a wooden ceiling.
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
2.5 star property
8.8
Excellent
1,002 reviews
View

Top Cape Romain National Wildlife Refuge Hotel Reviews

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

10/10 Excellent
"The staff was very gracious, the amenities were most enjoyable."
Rebecca 1-night trip
Posted 13 days ago
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Other attractions near Cape Romain National Wildlife Refuge

A golf course with a wooden bridge over water, surrounded by greenery and a clear blue sky.

Wild Dunes Resort Golf Course

8.8/10 (89 reviews)
Enjoy a round of golf in Isle of Palms at Wild Dunes Resort Golf Course. Stroll along the beautiful beaches in this family-friendly area or visit its top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Cape Romain National Wildlife Refuge?
If you're planning to come to the area to visit Cape Romain National Wildlife Refuge, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, you could search for properties close to public transport so it's easy to get around.
What's the best place to stay close to Cape Romain National Wildlife Refuge?
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn is one of the top choices for your stay based on our traveller data, and this resort offers 5 outdoor pools and a full-service spa. You'll find it 20.6 mi (33.2 km) from Cape Romain National Wildlife Refuge.
If I need to cancel the hotel reservation for my stay near Cape Romain National Wildlife Refuge, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer near Cape Romain National Wildlife Refuge.