Cape Girardeau hotels from RM295

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 May - 10 May
Tomorrow
10 May - 11 May
Next weekend
15 May - 17 May
In two weeks
22 May - 24 May

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Cape Girardeau hotels

Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,007 reviews)
"Clean room and wonderful staff. Great amenities "
United States
Myesha
The price is RM416
RM469 total
includes taxes & fees
20 May - 21 May
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (179 reviews)
"Nice room, good breakfast "
United States
KENNETH
The price is RM385
RM434 total
includes taxes & fees
20 May - 21 May
Fairfield Inn & Suites by Marriott Cape Girardeau
Snack bar

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (125 reviews)
"This is a clean, quiet, well designed hotel."
United States
Kendra
The price is RM383
RM435 total
includes taxes & fees
24 May - 25 May
Tru By Hilton Cape Girardeau
Free daily buffet breakfast

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,007 reviews)
"Clean room, friendly staff, great breakfast. "
United States
jessica
The price is RM369
RM416 total
includes taxes & fees
25 May - 26 May
Drury Inn & Suites Cape Girardeau
Desk, laptop workspace, blackout curtains, free cots/infant beds

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,005 reviews)
"Would stay again when in the area."
United States
Jack
The price is RM282
RM318 total
includes taxes & fees
7 Jun - 8 Jun
Pear Tree Inn Cape Girardeau West
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,006 reviews)
"Room was very clean. Breakfast was good with several options. Would recommend staying here."
United States
Linda
The price is RM412
RM464 total
includes taxes & fees
17 May - 18 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby sitting area

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (565 reviews)
"I ALWAYS stay here when I come to Cape! Wonderful, great place!"
United States
Audra
The price is RM517
RM583 total
includes taxes & fees
27 May - 28 May
The Riverview
Lobby

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (811 reviews)
"We enjoyed our stay"
United States
Wanda
The price is RM414
RM467 total
includes taxes & fees
31 May - 1 Jun
Hampton Inn Cape Girardeau I 55 East
Lobby

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
"We love staying at this inn. It truly feels like we’re in a friend’s beautifully appointed home. We’ll be back here again for certain. "
United States
Elsa
The price is RM587
RM663 total
includes taxes & fees
20 May - 21 May
Rockwood Inn
Lobby

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (738 reviews)
"It was good, but a noticeable hole in the wall above the toilet paper."
United States
Martin
The price is RM261
RM295 total
includes taxes & fees
31 May - 1 Jun
Quality Inn Cape Girardeau North
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (506 reviews)
"Great place! "
United States
Michelle
The price is RM526
RM596 total
includes taxes & fees
24 May - 25 May
Courtyard by Marriott Cape Girardeau Downtown
Exterior

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (930 reviews)
"Check in was so quick and friendly. The rooms were very clean. I slept so well but I like my beds super soft yet supportive."
United States
Justn
The price is RM313
RM374 total
includes taxes & fees
28 May - 29 May
Candlewood Suites Cape Girardeau by IHG
Desk, free WiFi

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (222 reviews)
"Easy to check in quite nice lil place "
United States
Damian
The price is RM293
RM343 total
includes taxes & fees
14 May - 15 May
Town House Inn Cape Giradreau
Lobby

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,007 reviews)
"Clean room, friendly staff, good breakfast and dinner variety,large open parking, clean pool and exercise room. All around great stay. "
United States
Jeremy
The price is RM357
RM377 total
includes taxes & fees
14 May - 15 May
Drury Inn & Suites Jackson MO
Lobby sitting area

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (90 reviews)
"Great place to stay! Nostalgic dining connected to hotel is pretty cool. If nearby, for sure stay with them."
United States
Jacob
The price is RM365
RM398 total
includes taxes & fees
11 May - 12 May
EC Reed's Mercantile and Hotel
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (761 reviews)
"Property was easily accessible and very clean!!"
United States
Denise
The price is RM384
RM415 total
includes taxes & fees
21 May - 22 May
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very good, (765 reviews)
"Beds felt amazing. My family and I had a great time"
United States
Gary
The price is RM360
RM390 total
includes taxes & fees
17 May - 18 May
Comfort Suites Jackson-Cape Girardeau
Indoor pool, outdoor pool

Hotel 7 Inn Anna

Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (222 reviews)
"Pool was broken unfortunately. The hotel is a little older and could use some updates but honestly the place was absolutely spotless! It smelled clean and fresh . Our bed was comfortable. The shower had great pressure and I could have stayed in there for hours lol . "
United States
Stephanie
The price is RM343
RM398 total
includes taxes & fees
11 May - 12 May
Hotel 7 Inn Anna
Private kitchen

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (441 reviews)
"Staff , room and sparkling pool were outstanding "
United States
James
The price is RM274
RM297 total
includes taxes & fees
10 May - 11 May
Town House Inn
Front of property – evening/night

Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (36 reviews)
"This is such a warm and inviting place to stay! The caretaker was very kind and available for any questions or needs, and made a great breakfast! It is clean and well-stocked with anything you might need. Will definitely be back! "
United States
Roxanne
The price is RM1,024
RM1,167 total
includes taxes & fees
24 May - 25 May
Makanda Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Cape Girardeau attractions

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau
Bill Emerson Memorial Bridge, Cape Girardeau, MO

Top Cape Girardeau Hotel Reviews

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent
"Breakfast as always was on point with biscuits, gravy, breakfast potatoes, Mediterranean scramble eggs. Love the Bavarian style design. Drury keeps setting the standards for happy travelers."
Matt 1-night trip
Posted 8 hours ago
Drury Inn & Suites Jackson MO

More cheap stays in Cape Girardeau

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO
The price is RM261 per night from 31 May to 1 Jun
RM261
RM295 total
31 May - 1 Jun
includes taxes & fees
7.2/10 Good! (738 reviews)

Frequently asked questions

What's the best place to stay in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is one of the top choices for your stay based on our traveller data. This hotel offers free breakfast and a restaurant. Other good options for your visit include The Riverview and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Cape Girardeau.
If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.
What's the best accommodation for a budget-friendly stay in Cape Girardeau?
Based on reviews, Pear Tree Inn Cape Girardeau West is a popular hotel for our travellers who want a more economical choice, and features free buffet breakfast and free Wi-Fi. View all budget hotels in Cape Girardeau.
What's the best family accommodation in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Pear Tree Inn Cape Girardeau West is another good option for your stay with the kids. Also, attractions such as Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are fun for children of all ages. Find more child-friendly accommodations in Cape Girardeau.
What's the best LGBTQ-friendly hotel in Cape Girardeau?
Pear Tree Inn Cape Girardeau Near the Medical Center is a top LGBTQ-friendly hotel, and features free Wi-Fi and LCD TVs. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Cape Girardeau.
What's the best dog-friendly hotel in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Pear Tree Inn Cape Girardeau West and Candlewood Suites Cape Girardeau by IHG. See more pet-friendly hotel accommodations in Cape Girardeau.
What are some accommodation options with pools in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top hotel with a pool, a full-service spa and free WiFi. View all hotels with pools in Cape Girardeau.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness centre. See all spa hotels in Cape Girardeau.
What is staying in Cape Girardeau like?
History buffs will enjoy exploring Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting and shopping. In Cape Girardeau, there are 62 hotels and other accommodation options to choose from. Find out more about Cape Girardeau.
What should I do while I'm visiting Cape Girardeau?
Favorite family attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. Landmarks like The Glenn House and Fort D Historic Site might be worth a visit. Natural beauty is on display at Shawnee National Forest, Mississippi River and Cape Rock Park. Take a look at what more there is to see and do in Expedia's Cape Girardeau guide.
What's the weather like in Cape Girardeau?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.

Explore a world of travel with Expedia