A large suspension bridge, industrial cranes, and a calm river.

Five Star Hotels in Panama Canal Zone

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Check availability on Panama Canal Zone 5 Star Hotels

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Panama Canal Zone 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A modern hotel room with a dining area, a TV, and a city view.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Avanel
RM539
RM593 total
includes taxes & fees
21 Oct - 22 Oct
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
RM1,073
RM1,180 total
includes taxes & fees
31 Oct - 1 Nov
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
RM1,434
RM1,577 total
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
RM552
RM607 total
includes taxes & fees
31 Oct - 1 Nov
Renaissance Panama City Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Detra Dorsey
RM1,141
RM1,255 total
includes taxes & fees
7 Nov - 8 Nov
JW Marriott Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern interior with a central seating area, potted plants, and a staircase.

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Mariah
RM764
RM840 total
includes taxes & fees
17 Oct - 18 Oct
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A pool with a central water feature, surrounded by seating areas and potted plants.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Carmen
RM1,131
RM1,244 total
includes taxes & fees
1 Nov - 2 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.

8. W Panama

W Panama
Bella Vista
United States
Naomi
RM945
RM1,039 total
includes taxes & fees
1 Nov - 2 Nov
W Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern bar area with seating and a view of the city.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Simon
RM1,004
RM1,104 total
includes taxes & fees
6 Nov - 7 Nov
Hilton Panama
A hotel with a pool, beach, and palm trees.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Anna
RM842
RM926 total
includes taxes & fees
25 Oct - 26 Oct
The Westin Playa Bonita Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
RM1,017
RM1,119 total
includes taxes & fees
17 Oct - 18 Oct
Bristol Panama, a Registry Collection Hotel
Breakfast area
Banquet hall
Bar (on property)
Outdoor pool

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
RM415
RM459 total
includes taxes & fees
2 Nov - 3 Nov
Waymore Hotel Spa and Casino
Terrace/patio
Casino
Outdoor pool
Room

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
RM1,066
RM1,178 total
includes taxes & fees
4 Nov - 5 Nov
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
RM568
RM652 total
9 Nov - 10 Nov
includes taxes & fees
8.6/10 Excellent! (2,756 reviews)
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
RM830
RM913 total
9 Nov - 10 Nov
includes taxes & fees
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
RM668
RM734 total
31 Oct - 1 Nov
includes taxes & fees
8.6/10 Excellent! (1,778 reviews)
Megapolis Hotel Panamá
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—rainforests, golf courses and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
A large suspension bridge, industrial cranes, and a calm river.

Top Panama Canal Zone Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

8/10 Good
"Housekeeping did an excellent job cleaning the room daily. However, there were some maintenance items that needed attention. Half of the plug receptacles in the room were inoperable. The frosted glass wall between the bathroom and room was very pretty. However when anyone got up in the middle of the night to use the toilet, the lights shined right through and lit up the entire room. All of the staff were very friendly and very helpful. They made our stay pleasant. The daily breakfast buffet had a wonderful selection of dishes and fresh juices. Everything was delicious. The bar and restaurant at the pool had good drinks and food. However, I did not like the policy of no outside food or drinks when sitting at the pool. So if you purchased something from the coffee/snack shop you could not take it to the pool area. Additionally, after spending a day in/at the pool, we were told we could not take the towel out of the pool area. Couldn’t take a piece of fruit out of the breakfast buffet. Too many restrictive rules. The employees acted like they were the police at every area of the hotel. When I questioned one of them asking why they are acting like the police, he replied that he would get in trouble if he let anything slip. It appeared he was being watched. Not just him, but all of the employees. I was not intentionally trying to break any rules. I have stayed at many other Riu Resorts in different countries and I did not feel like we were policed everywhere like at this resort."
Kimberly 4-night trip
Posted 5 hours ago
Hotel Riu Plaza Panama

Find out more about Panama Canal Zone

Stay in Luxury: 5 Star Hotels in Panama Canal Zone

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Panama Canal Zone trip. You'll join the multitudes of holidaymakers who have made Panama Canal Zone so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Panama Canal Zone and indulge in the finer things in life for a while.

5-Star Hotels in Panama Canal Zone

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Panama Canal Zone are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Panama Canal Zone 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Panama Canal Zone! Choose one of our Panama Canal Zone 5-star hotels today and soothe yourself in luxe surroundings at your convenience.

Expedia India is rated 4 stars by Feefo based on 1038 reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone depends on factors such as when you want to go and the length of your trip. A top tip for scoring the best deal? Use our pricing filters to compare all of the available accommodation for your chosen dates.
  • Search for the lowest price per night from RM652
What makes a hotel 5 stars in Panama Canal Zone?
Faultless guest service is integral to every 5-star hotel in Panama Canal Zone. From the moment you enter the lobby, staff ensure your every need is met, whether arranging valet parking or providing in-room massage treatments. Additionally, hotels have to offer upscale conveniences to obtain a 5-star rating. These can include deluxe baths, an on-site spa, pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Our filter tool is the best way to narrow down what you want. Select "5-star" and "All inclusive" to see the most upscale hotels in Panama Canal Zone where your meals, accommodation, activities and entertainment are included in the price. At these getaways, your trip is pure indulgence from the moment you step foot in the lobby.