A beach with clear turquoise water and a large brick building on the shore.

Five Star Hotels in Gulf of Mexico

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Gulf of Mexico 5 Star Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Gulf of Mexico 5-star hotels

A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.

1. Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,509 reviews)
"Great place. Phenomenal food!"
United States
Brandon
The price is RM734
RM1,122 total
includes taxes & fees
19 Nov - 20 Nov
Cheeca Lodge & Spa
A grand hallway with a central statue, flanked by rows of Christmas trees adorned with lights and red ribbons.

2. The Roosevelt New Orleans, A Waldorf Astoria Hotel

The Roosevelt New Orleans, A Waldorf Astoria Hotel
5.0 star property
New Orleans Central Business District
9.4 out of 10, Exceptional, (1,003 reviews)
"Hotel has old character but updated nicely."
United States
Rashonner
The price is RM965
RM1,142 total
includes taxes & fees
22 Nov - 23 Nov
The Roosevelt New Orleans, A Waldorf Astoria Hotel
A hotel entrance with a dark awning, glass doors, and a staircase leading up.

3. The Windsor Court

The Windsor Court
5.0 star property
New Orleans Central Business District
9.8 out of 10, Exceptional, (1,002 reviews)
"Beautiful hotel, comfy beds and great location. Staff were really friendly and helpful. We had a fantastic stay here and would highly recommend!"
United Kingdom
Sarah
The price is RM1,603
RM1,892 total
includes taxes & fees
22 Nov - 23 Nov
The Windsor Court
An aerial view of a resort with a central pool, multiple buildings, and a beach area with sun loungers.

4. Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,302 reviews)
"Amazing hotel"
United States
Yamila
The price is RM899
RM1,256 total
includes taxes & fees
9 Nov - 10 Nov
Isla Bella Beach Resort & Spa
A modern lounge area with a sofa, chairs, and a coffee table, surrounded by bookshelves and potted plants.

5. Four Seasons Hotel New Orleans

Four Seasons Hotel New Orleans
5.0 star property
New Orleans Central Business District
9.6 out of 10, Exceptional, (774 reviews)
"Beautiful property, room and staff was very helpful and attentive!"
United States
Richard
The price is RM2,122
RM2,501 total
includes taxes & fees
25 Nov - 26 Nov
Four Seasons Hotel New Orleans
A spacious room with a large window, a sofa, armchairs, and a coffee table.

6. The Ritz-Carlton, New Orleans

The Ritz-Carlton, New Orleans
5.0 star property
French Quarter
9.2 out of 10, Wonderful, (1,000 reviews)
"Great place to stay and great location."
United States
John
The price is RM1,029
RM1,403 total
includes taxes & fees
22 Nov - 23 Nov
The Ritz-Carlton, New Orleans
A luxurious indoor space with a central staircase, surrounded by lush greenery and elegant furnishings.

7. The Tampa EDITION

The Tampa EDITION
5.0 star property
Downtown Tampa
9.4 out of 10, Exceptional, (445 reviews)
"Everything excellent."
United States
Denis
The price is RM1,454
RM1,841 total
includes taxes & fees
22 Nov - 23 Nov
The Tampa EDITION
A beachfront property with a large building, sandy beach, and ocean.

8. The Henderson Beach Resort & Spa

The Henderson Beach Resort & Spa
5.0 star property
Crystal Beach
9.2 out of 10, Wonderful, (1,003 reviews)
"We enjoyed our stay"
United States
Charles
The price is RM1,078
RM1,442 total
includes taxes & fees
15 Nov - 16 Nov
The Henderson Beach Resort & Spa
A pool area with lounge chairs and palm trees, overlooking the ocean at sunset.

9. The Ritz-Carlton, Sarasota

The Ritz-Carlton, Sarasota
5.0 star property
Central Sarasota
9.2 out of 10, Wonderful, (1,019 reviews)
"The staff was professional and extremely helpful! The grounds and room was clean and well maintained!"
United States
Patricia
The price is RM2,165
RM2,710 total
includes taxes & fees
6 Dec - 7 Dec
The Ritz-Carlton, Sarasota
A checkered floor, a dark wall with a 'CONCIERGE' sign, a counter with a decorative grille, and a chandelier.

10. Maison Métier, in the Unbound Collection by Hyatt

Maison Métier, in the Unbound Collection by Hyatt
5.0 star property
New Orleans Central Business District
9.8 out of 10, Exceptional, (322 reviews)
"Lovely visit! Would definitely stay here again!!"
United States
Katherine
The price is RM1,811
RM2,296 total
includes taxes & fees
15 Nov - 16 Nov
Maison Métier, in the Unbound Collection by Hyatt
A modern living room with a sofa, two side chairs, a coffee table, and a TV.

11. The Mayfair

The Mayfair
5.0 star property
French Quarter
10.0 out of 10, Exceptional, (71 reviews)
"Great location, elegant rooms & fun town to visit"
United States
Michael L
The price is RM699
RM1,354 total
includes taxes & fees
9 Nov - 10 Nov
The Mayfair
A pool area with lounge chairs, a small pool, and indoor plants.

12. Fairmont New Orleans (Opening November 2026)

Fairmont New Orleans (Opening November 2026)
5.0 star property
New Orleans Central Business District
The price is RM1,818
RM2,307 total
includes taxes & fees
22 Nov - 23 Nov
Fairmont New Orleans (Opening November 2026)
A modern kitchen with a large island, white cabinetry, and a dining area with a table and chairs.

13. The Gemma by Brightwild

The Gemma by Brightwild
5.0 star property
Clearwater Beach
9.8 out of 10, Exceptional, (7 reviews)
"The house was beautiful and the location was perfect for our family."
United States
William
The price is RM2,863
RM5,958 total
includes taxes & fees
8 Nov - 9 Nov
The Gemma by Brightwild
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Gulf of Mexico.
IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

850 Bayview Ave Biloxi MS
The price is RM280 per night from 22 Nov to 23 Nov
RM280
RM396 total
22 Nov - 23 Nov
includes taxes & fees
Still don't see what you're looking for?
See all properties in Gulf of Mexico.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Gulf of Mexico

Plan your trip to Gulf of Mexico and take advantage of the sights and activities in the area.

See all hotels in Gulf of Mexico
A beach with clear turquoise water and a large brick building on the shore.

Top Gulf of Mexico Hotel Reviews

Find out more about Gulf of Mexico

Stay in Luxury: 5 Star Hotels in Gulf of Mexico

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Gulf of Mexico trip. You'll join the multitudes of holidaymakers who have made Gulf of Mexico so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Gulf of Mexico and indulge in the finer things in life for a while.

5-Star Hotels in Gulf of Mexico

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Gulf of Mexico are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Gulf of Mexico 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Gulf of Mexico! Choose one of our Gulf of Mexico 5-star hotels today and soothe yourself in luxe surroundings at your convenience.


Expedia India is rated 4 stars by Feefo based on 1038 reviews