
Popular airlines from Colón
Avianca
United
American Airlines
Copa
Delta
Aeromexico
KLM
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheapest flights from Colón
These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, 5 Mar - Mon, 9 Mar
PTY
Panama City
MIA
Miami
RM1,451 Return, found 10 hours ago
RM1,451
Return
found 10 hours ago

Mon, 9 Mar - Mon, 6 Apr
PTY
Panama City
CUN
Cancun
RM1,520 Return, found 3 days ago
RM1,520
Return
found 3 days ago

Mon, 9 Mar - Mon, 6 Apr
PTY
Panama City
CUN
Cancun
RM1,625 Return, found 3 days ago
RM1,625
Return
found 3 days ago

Mon, 9 Mar - Mon, 6 Apr
PTY
Panama City
CUN
Cancun
RM1,711 Return, found 3 days ago
RM1,711
Return
found 3 days ago

Mon, 9 Mar - Mon, 6 Apr
PTY
Panama City
CUN
Cancun
RM1,745 Return, found 3 days ago
RM1,745
Return
found 3 days ago

Mon, 9 Mar - Mon, 6 Apr
PTY
Panama City
CUN
Cancun
RM1,771 Return, found 3 days ago
RM1,771
Return
found 3 days ago

Mon, 9 Mar - Mon, 6 Apr
PTY
Panama City
CUN
Cancun
RM1,837 Return, found 3 days ago
RM1,837
Return
found 3 days ago

Mon, 9 Mar - Mon, 6 Apr
PTY
Panama City
CUN
Cancun
RM1,850 Return, found 3 days ago
RM1,850
Return
found 3 days ago

Thu, 5 Mar - Mon, 9 Mar
PTY
Panama City
MIA
Miami
RM1,988 Return, found 10 hours ago
RM1,988
Return
found 10 hours ago

Thu, 30 Apr - Tue, 5 May
PTY
Panama City
JFK
New York
RM2,159 Return, found 1 day ago
RM2,159
Return
found 1 day ago
Explore a world of travel with Expedia
*Available to Expedia members.