Hotels in Zona 21, Guatemala City

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Our top choices for Zona 21 hotels

Why Not Hotel

Why Not Hotel
3.0 star property
20.3 km from Zona 21
8.4 out of 10, Very good, (149)
"clean and spacious room "
Italy
Teresa
The price is RM160
RM196 total
includes taxes & fees
1 Jan - 2 Jan 2026
Why Not Hotel

Hotel Panchoy

Hotel Panchoy
3.0 star property
19.7 km from Zona 21
8.4 out of 10, Very good, (275)
"Nice staff and good location "
United States
Luis
The price is RM201
RM245 total
includes taxes & fees
24 Dec - 25 Dec
Hotel Panchoy

Barceló Guatemala City

Barceló Guatemala City
4.5 star property
Zona 9, 6.1 km from Zona 21
9.2 out of 10, Wonderful, (3122)
"Breakfast with room service was very good."
United States
Gary
The price is RM336
RM409 total
includes taxes & fees
3 Jan - 4 Jan 2026
Barceló Guatemala City

Hostal Donde Regina

Hostal Donde Regina
3.0 star property
Zona 13, 4.4 km from Zona 21
9.2 out of 10, Wonderful, (169)
"Spotless room and good staff service"
United States
Christian
The price is RM196
RM239 total
includes taxes & fees
30 Dec - 31 Dec
Hostal Donde Regina

In & Out Hotel

In & Out Hotel
3.0 star property
Zona 13, 4.4 km from Zona 21
8.6 out of 10, Excellent, (808)
"Clean room , helpful staff for getting a taxi, loved full breakfast"
United States
Deborah
In & Out Hotel

Hotel La Sin Ventura

Hotel La Sin Ventura
2.0 star property
20.2 km from Zona 21
8.8 out of 10, Excellent, (146)
"Really glad we stayed here. This hotel has the best staff ever. Perfect location. "
United States
Greg
Hotel La Sin Ventura

Hotel Don Felipe Airport

Hotel Don Felipe Airport
2.0 star property
Zona 13, 3.8 km from Zona 21
8.0 out of 10, Very good, (24)
"Close to the airport "
United States
Alejandro
Hotel Don Felipe Airport

Hostal los Volcanes ciudad de Guatemala

Hostal los Volcanes ciudad de Guatemala
3.0 star property
Zona 13, 4 km from Zona 21
8.8 out of 10, Excellent, (60)
"Really good place!"
United States
Eddy
Hostal los Volcanes ciudad de Guatemala

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
Zona 4, 8.4 km from Zona 21
9.4 out of 10, Exceptional, (248)
"Great place to stay in the city"
United States
Cesar
The price is RM391
RM477 total
includes taxes & fees
24 Dec - 25 Dec
Good Hotel Guatemala City

Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center
4.5 star property
Zona 11, 8.3 km from Zona 21
9.0 out of 10, Wonderful, (1008)
"Great place to stay and relax. Beautiful rooms and great staff"
United States
Tracy
The price is RM436
RM532 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tikal Futura Hotel & Convention Center

Clarion Suites Guatemala City

Clarion Suites Guatemala City
4.0 star property
Zona 10, 6.4 km from Zona 21
9.0 out of 10, Wonderful, (1012)
"Loved the stay here!"
United States
Nora
The price is RM414
RM505 total
includes taxes & fees
3 Jan - 4 Jan 2026
Clarion Suites Guatemala City

Las Camelias Inn

Las Camelias Inn
3.0 star property
19.8 km from Zona 21
8.8 out of 10, Excellent, (580)
"Very good place for my stay in Antigua. They were so helpful in storing my luggages away even after check out for a whole day for free when I went for the volcano hike. "
Canada
Joel
The price is RM302
RM368 total
includes taxes & fees
24 Dec - 25 Dec
Las Camelias Inn

Wyndham Garden Guatemala City

Wyndham Garden Guatemala City
4.0 star property
Zona 10, 6.6 km from Zona 21
9.2 out of 10, Wonderful, (1624)
"Location and hotel is amazing and the staff is very helpful"
United States
Martha
The price is RM409
RM499 total
includes taxes & fees
4 Jan - 5 Jan 2026
Wyndham Garden Guatemala City

Villas Santander - Deluxe Stay

Villas Santander - Deluxe Stay
3.0 star property
Zona 10, 6.7 km from Zona 21
7.4 out of 10, Good, (224)
"The balcony view was a little scenic. Enjoyed how clean the rooms were "
United States
Rosa
The price is RM167
RM204 total
includes taxes & fees
24 Dec - 25 Dec
Villas Santander - Deluxe Stay

La Capitania de San Pedro

La Capitania de San Pedro
2.5 star property
20.7 km from Zona 21
10.0 out of 10, Exceptional, (5)
" La Capitanía de San Pedro was absolutely beautiful! The views, atmosphere, and hospitality made it unforgettable. I’d recommend it to anyone visiting Antigua Guatemala truly a perfect 10/10 experience!"
United States
Rudy
The price is RM281
RM343 total
includes taxes & fees
26 Dec - 27 Dec
La Capitania de San Pedro

Adriatika Hotel & Residence

Adriatika Hotel & Residence
4.5 star property
Zona 14, 3.8 km from Zona 21
9.4 out of 10, Exceptional, (952)
"Great stay"
United States
Alejandro
The price is RM408
RM498 total
includes taxes & fees
29 Dec - 30 Dec
Adriatika Hotel & Residence

Kawilal Hotel

Kawilal Hotel
3.5 star property
10.3 km from Zona 21
9.0 out of 10, Wonderful, (132)
"Beautiful pool and spa with thermal water! Only hotel guests are allowed to have use of the installations. The massage was amazing! I would love to go back "
United States
Ana
The price is RM440
RM536 total
includes taxes & fees
6 Jan - 7 Jan 2026
Kawilal Hotel

Hotel España

Hotel España
3.0 star property
Guatemala City Historical District, 10 km from Zona 21
7.4 out of 10, Good, (18)
"Nice place !!! "
United States
NERY
The price is RM105
RM128 total
includes taxes & fees
24 Dec - 25 Dec
Hotel España

Hotel Casa Carmina

Hotel Casa Carmina
4.0 star property
20.3 km from Zona 21
9.0 out of 10, Wonderful, (211)
"Room looked great, super clean, staff was friendly, very gorgeous hotel"
United States
Blondia
The price is RM309
RM377 total
includes taxes & fees
24 Dec - 25 Dec
Hotel Casa Carmina

Hotel Posada de Don Rodrigo Antigua

Hotel Posada de Don Rodrigo Antigua
3.5 star property
20.2 km from Zona 21
9.4 out of 10, Exceptional, (652)
"Friendly staff, clean rooms the location was excellent. "
United States
Elias
The price is RM656
RM899 total
includes taxes & fees
28 Dec - 29 Dec
Hotel Posada de Don Rodrigo Antigua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Zona 21

Find the best Zona 21 areas for the activities you enjoy most.

Zona 10

Zona 10 is known for its abundant dining options, and you can plan a trip to Oakland Mall and Plaza Fontabella Shopping Center while you're in town.

Zona 1

Zona 1 is noteworthy for its historical sites, and you can make a stop at top attractions like Constitution Square and Guatemala City Hall.

Zona 9

Travellers come to Zona 9 for its abundant dining options, and you can see top attractions like Avenida La Reforma and Torre del Reformador while you're in town.

Zona 13

Zona 13 is noteworthy for its gardens, and you can make a stop at top attractions like Avenida Las Américas and El Obelisco.

Zona 16

Travellers like the festivals in Zona 16, and Paseo Cayala is a top attraction you might want to visit.

Top Zona 21 Hotel Reviews

Frequently asked questions

What's it like in Zona 21?
Travellers are sure to enjoy a stay in Guatemala City's Zona 21 neighbourhood.
If I need to cancel my hotel reservation in Zona 21, will I receive a refund?
Yes, most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in Zona 21.
What is there to do around this Guatemala City neighbourhood?
Mundo Petapa, Guatemalan Exporters Association and Parque Las Américas are just a few of the places to visit in and around Zona 21. When you're sightseeing in Guatemala City, Embassy of Peru and Avenida Las Américas are also worth a stop.