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Upstate South Carolina hotels from RM271
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Go beyond your typical stay in Upstate South Carolina
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Check prices for these dates
Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
10.0 out of 10, Exceptional, (3 reviews)
The price is RM222
RM246 total
includes taxes & fees
9 Jun - 10 Jun

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (729 reviews)
The price is RM329
RM358 total
includes taxes & fees
28 Jun - 29 Jun

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very good, (710 reviews)
The price is RM341
RM400 total
includes taxes & fees
11 Jun - 12 Jun

Deluxe Inn
Deluxe InnMauldin
9.6 out of 10, Exceptional, (4 reviews)
The price is RM254
RM279 total
includes taxes & fees
9 Jun - 10 Jun

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,497 reviews)
The price is RM329
RM362 total
includes taxes & fees
14 Jun - 15 Jun

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (234 reviews)
The price is RM521
RM573 total
includes taxes & fees
14 Jun - 15 Jun

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (919 reviews)
The price is RM338
RM375 total
includes taxes & fees
5 Jul - 6 Jul

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,010 reviews)
The price is RM439
RM545 total
includes taxes & fees
9 Jun - 10 Jun

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (623 reviews)
The price is RM443
RM492 total
includes taxes & fees
14 Jun - 15 Jun

Fairfield Inn & Suites by Marriott Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville SimpsonvilleSimpsonville
9.0 out of 10, Wonderful, (728 reviews)
The price is RM322
RM354 total
includes taxes & fees
21 Jun - 22 Jun

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
8.6 out of 10, Excellent, (247 reviews)
The price is RM348
RM395 total
includes taxes & fees
21 Jun - 22 Jun

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (743 reviews)
The price is RM464
RM519 total
includes taxes & fees
20 Jun - 21 Jun

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (554 reviews)
The price is RM255
RM300 total
includes taxes & fees
4 Jul - 5 Jul

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,004 reviews)
The price is RM560
RM622 total
includes taxes & fees
10 Jun - 11 Jun

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very good, (1,004 reviews)
The price is RM384
RM426 total
includes taxes & fees
9 Jun - 10 Jun

Hilton Garden Inn Anderson
Hilton Garden Inn AndersonAnderson
9.0 out of 10, Wonderful, (730 reviews)
The price is RM400
RM444 total
includes taxes & fees
14 Jun - 15 Jun

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (845 reviews)
The price is RM426
RM469 total
includes taxes & fees
5 Jul - 6 Jul

Inn @ Clemson
Inn @ ClemsonClemson
8.0 out of 10, Very good, (1,007 reviews)
The price is RM323
RM358 total
includes taxes & fees
9 Jun - 10 Jun

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (499 reviews)
The price is RM359
RM391 total
includes taxes & fees
21 Jun - 22 Jun

Days Inn by Wyndham Anderson
Days Inn by Wyndham AndersonAnderson
8.0 out of 10, Very good, (1,011 reviews)
The price is RM236
RM262 total
includes taxes & fees
10 Jun - 11 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (78 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites
10/10 Excellent
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is RM244 per night from 9 Jul to 10 Jul
RM244
RM271 total
9 Jul - 10 Jul
includes taxes & fees
6/10 (612 reviews)

4 Star Hotels
35 properties
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