Photo by Michelle Hendrix
Upstate South Carolina hotels from RM256
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Upstate South Carolina
Check prices for these dates
Our top choices for Upstate South Carolina hotels
Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (437 reviews)
"Great people n place"
Janice
The price is RM317
RM345 total
includes taxes & fees
25 Jan - 26 Jan
Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,001 reviews)
"Great place to stay. "
Gene
The price is RM442
RM549 total
includes taxes & fees
19 Jan - 20 Jan
Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.0 out of 10, Wonderful, (1,434 reviews)
"Excellent hotel nice and clean. "
Irasema
The price is RM314
RM346 total
includes taxes & fees
25 Jan - 26 Jan
La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
La Quinta by Wyndham Haywood Mall-Near Greenville DowntownGreenville
7.4 out of 10, Good, (1,133 reviews)
"Kind staff, clean room, tasty continental breakfast!"
Karen
The price is RM248
RM273 total
includes taxes & fees
1 Feb - 2 Feb
Comfort Suites Greenville Airport
Comfort Suites Greenville AirportGreenville
9.2 out of 10, Wonderful, (1,001 reviews)
"We stayed here based on proximity to GSP airport. It was clean, parking lot was well lit, room was spacious and comfortable. Would stay here again."
Lawrence
The price is RM384
RM433 total
includes taxes & fees
24 Jan - 25 Jan
The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (792 reviews)
"Clean room, great location, wonderful staff!"
Joyce
The price is RM605
RM671 total
includes taxes & fees
19 Jan - 20 Jan
Hampton Inn Spartanburg-North I-85
Hampton Inn Spartanburg-North I-85Spartanburg
8.6 out of 10, Excellent, (1,000 reviews)
"Great staff, clean room, good location. Would definitely stay here again!"
Randall
The price is RM329
RM365 total
includes taxes & fees
24 Jan - 25 Jan
Aloft Greenville Downtown
Aloft Greenville DowntownGreenville Downtown
9.2 out of 10, Wonderful, (1,002 reviews)
"Room was very clean, the staff was great and the location was perfect!"
Mike
The price is RM492
RM541 total
includes taxes & fees
25 Jan - 26 Jan
DoubleTree by Hilton Greenville Woodruff Road
DoubleTree by Hilton Greenville Woodruff RoadGreenville
9.4 out of 10, Exceptional, (1,001 reviews)
"Desk Staff was very kind and helpful. Room was very clean. Overall a wonderful stay"
Robin
The price is RM445
RM489 total
includes taxes & fees
1 Feb - 2 Feb
SpringHill Suites by Marriott Greenville Downtown
SpringHill Suites by Marriott Greenville DowntownGreenville Downtown
9.6 out of 10, Exceptional, (1,001 reviews)
"Great spot and beautiful hotel!"
Lisa
The price is RM508
RM558 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.0 out of 10, Wonderful, (586 reviews)
"It was great. Room was clean and staff was friendly. "
Veronica
The price is RM418
RM464 total
includes taxes & fees
24 Jan - 25 Jan
Embassy Suites by Hilton Greenville Downtown Riverplace
Embassy Suites by Hilton Greenville Downtown RiverplaceGreenville Downtown
9.2 out of 10, Wonderful, (1,005 reviews)
"We really enjoyed our stay! "
Frances
The price is RM597
RM656 total
includes taxes & fees
25 Jan - 26 Jan
Hyatt Place Greenville Downtown
Hyatt Place Greenville DowntownGreenville Downtown
9.2 out of 10, Wonderful, (1,006 reviews)
"Great stay downtown! Close to everything and staff were wonderful! Breakfast had a good variety and was delicious! Will definitely be staying here again."
Whitney
The price is RM495
RM545 total
includes taxes & fees
25 Jan - 26 Jan
Home2 Suites by Hilton Anderson Downtown
Home2 Suites by Hilton Anderson DowntownAnderson
9.4 out of 10, Exceptional, (221 reviews)
"Great hotel. "
scott
The price is RM568
RM630 total
includes taxes & fees
25 Jan - 26 Jan
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
8.6 out of 10, Excellent, (99 reviews)
"Great room, very clean and staff was friendly "
James
The price is RM292
RM331 total
includes taxes & fees
23 Jan - 24 Jan
Drury Inn & Suites Greenville
Drury Inn & Suites GreenvilleGreenville
9.4 out of 10, Exceptional, (1,004 reviews)
"Clean rooms and staff is always friendly. Great breakfast "
Terry
The price is RM438
RM482 total
includes taxes & fees
22 Jan - 23 Jan
Hampton Inn Anderson/ Alliance Business Park
Hampton Inn Anderson/ Alliance Business ParkAnderson
9.2 out of 10, Wonderful, (819 reviews)
"Staff, Just a Nice Hotel"
Christopher
The price is RM443
RM492 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Anderson by IHG
Holiday Inn Anderson by IHGAnderson
8.8 out of 10, Excellent, (700 reviews)
"Clean, great breakfast, convenient location"
Reggie
The price is RM426
RM473 total
includes taxes & fees
17 Feb - 18 Feb
Wingate by Wyndham - Greenville-Airport
Wingate by Wyndham - Greenville-AirportGreenville
8.4 out of 10, Very good, (1,002 reviews)
"Nice stay"
Komal
The price is RM325
RM358 total
includes taxes & fees
21 Jan - 22 Jan
Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,027 reviews)
"Great stay. "
kurt
The price is RM383
RM421 total
includes taxes & fees
25 Jan - 26 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cottage
9.8 out of 10, Exceptional, (9 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southeastern United States attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.
Photo by Michelle Hendrix
Open Photo by Michelle Hendrix
Top Upstate South Carolina Hotel Reviews
Best Western Plus Greenville I-385 Inn & Suites
10/10 Excellent
More cheap stays in Upstate South Carolina
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
The price is RM255 per night from 20 Jan to 21 Jan
RM255
RM283 total
20 Jan - 21 Jan
includes taxes & fees
7.8/10 Good! (1,004 reviews)
4 Star Hotels
11 properties
Explore a world of travel with Expedia
- Condominium Resorts in Anderson County
- Anderson Hotels
- Boiling Springs Hotels
- Central Hotels
- Cross Hill Hotels
- Red Roof Inn Hotels in Duncan
- Duncan Hotels
- Gay friendly Hotels in Easley
- Easley Hotels
- Fountain Inn Hotels
- Gramling Hotels
- Hotels near Greenville Downtown
- Greenville Downtown Hotels
- Greenville Hotels
- Hotels with smoking rooms in Greenville - Spartanburg
- Greenwood Hotels
- Motel 6 Hotels in Inman
- Iva Hotels
- Joanna Hotels
- Mauldin Hotels
- Hotels near Southern Wesleyan University
- Spartanburg Hotels
- Starr Hotels
- Sunset Hotels
- Taylors Hotels
- Union Hotels
- Motel 6 Hotels in Upstate South Carolina
- Gay friendly Hotels in West End
- Hotels near WestGate Mall
- Woodruff Hotels
- Flights to Startex
- Flights from Honea Path
- Flights from Startex
- Flights from Gray Court
- Flights from Greenville - Spartanburg
- Flights from Taylors
- Flights from Fountain Inn
- Flights from Lake Of The Ozarks (AIZ) to Greenville (GSP)
- Flights from Anderson (AND) to Pickens (LQK)
- Flights from Bar Harbor (BHB) to Greenville (GSP)
- Flights from León (BJX) to Greenville (GSP)
- Flights from Christchurch (CHC) to Greenville (GSP)
- Flights from Corumba (CMG) to Pickens (LQK)
- Flights from Changsha (CSX) to Greenville (GSP)
- Flights from Daytona Beach (DAB) to Spartanburg (SPA)
- Flights from Entebbe (EBB) to Greenville (GSP)
- Flights from Eagle River (EGV) to Greenville (GSP)
- Flights from Nancy (ENC) to Greenville (GSP)
- Flights from Yopal (EYP) to Greenville (GSP)
- Flights from Faro (FAO) to Greenville (GSP)
- Flights from Florence (FLO) to Greenville (GSP)
- Flights from Gaya (GAY) to Greenville (GSP)
- Flights from Iron Mountain (IMT) to Greenville (GSP)
- Flights from Kuala Lumpur (KUL) to Greenville (GSP)
- Flights from Los Angeles (LAX) to Greenville (GSP)
- Flights from Leesburg (LEE) to Greenville (GSP)
- Flights from Lexington (LEX) to Greenville (GSP)
- Flights from Mackinac Island (MCD) to Greenville (GSP)
- Flights from Medellín (MDE) to Greenville (GSP)
- Flights from Melbourne (MEL) to Greenville (GSP)
- Flights from Moses Lake (MWH) to Greenville (GSP)
- Flights from Myrtle Beach (MYR) to Greenville (GSP)
- Flights from Ocala (OCF) to Greenville (GSP)
- Flights from Paris (PAR) to Greenville (GDC)
- Flights from Phoenix (PHX) to Pickens (LQK)
- Flights from Pittsburgh (PIT) to Pickens (LQK)
- Flights from Providenciales (PLS) to Greenville (GSP)
- Flights from Rogers (ROG) to Greenville (GSP)
- Flights from Schenectady (SCH) to Greenville (GSP)
- Flights from Stuttgart (STR) to Greenville (GSP)
- Flights from Tirana (TIA) to Greenville (GSP)
- Flights from Washington (WAS) to Greenville (GDC)
- Flights from Arviat (YEK) to Pickens (LQK)
- Flights from Sydney (YQY) to Greenville (GSP)
- Visit Arial
- Cedar Lane Shopping Center
- Centre West Shopping Center
- Conestee Nature Preserve
- Frankie's Fun Park
- Golden Lanes and Golden Skate
- Visit Gramling
- Visit Greenville Downtown
- Greenville Holidays
- Heritage Green
- Hollywild Animal Park
- Honea Path Holidays
- Visit Honea Path
- Inman Holidays
- Logos Theatre
- Visit Startex
- Topgolf Greenville
- Wade Hampton Plaza Shopping Center
- Visit Wellford
- Younts Center for Performing Arts
