Best Luxury Hotels in Syracuse

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Syracuse Luxury Hotels

This weekend
Next weekend

Our top choices for Syracuse luxury hotels

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia
9.6 out of 10, Exceptional, (73 reviews)
"Location, staff were amazing"
Canada
Jared
The price is RM2,500
RM2,796 total
includes taxes & fees
3 May - 4 May
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
5.0 star property
Syracuse
9.6 out of 10, Exceptional, (94 reviews)
"This was such a wonderful stay! Spotless beautiful property with friendly staff and delicious breakfast!!! Very impressed!"
United States
Jeffrey
The price is RM1,481
RM1,676 total
includes taxes & fees
21 Apr - 22 Apr
Wellness & Spa Hotel Principe di Fitalia

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.4 out of 10, Exceptional, (259 reviews)
"The hotel itself is a beautiful building with an interesting heritage as the main post office. The location is excellent offering a great starting point for a walking tour of Ortigia. Great stay."
Canada
Craig
The price is RM1,563
RM1,766 total
includes taxes & fees
10 Apr - 11 Apr
Ortea Palace Hotel, Sicily, Autograph Collection

Minareto

Minareto
5.0 star property
Syracuse
8.8 out of 10, Excellent, (267 reviews)
"Very convenient for swimming and relaxing. "
Canada
Stanislau
The price is RM1,518
RM1,763 total
includes taxes & fees
3 May - 4 May
Minareto

Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (211 reviews)
"We experienced outstanding service from all of the staff, the breakfast buffet was lovely, lots of options and all homemade. We had a fantastic dinner in the restaurant one evening, which we booked ahead of our trip. "
United Kingdom
David
The price is RM1,306
RM1,483 total
includes taxes & fees
10 Apr - 11 Apr
Dimora Caiammari Luxury Hotel & Spa

Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
4.0 star property
Ortigia
9.4 out of 10, Exceptional, (664 reviews)
"In général, it’s a great place to stay."
Canada
Alfredo Ernesto
The price is RM1,479
RM1,674 total
includes taxes & fees
8 Apr - 9 Apr
Palazzo Artemide - VRetreats, SLH Collection

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (937 reviews)
"Excellent breakfast and wonderful staff. Location is great"
United Kingdom
Bert O
The price is RM1,341
RM1,521 total
includes taxes & fees
12 Apr - 13 Apr
Algila' Ortigia Charme Hotel

Charme Hotel Henry's House

Charme Hotel Henry's House
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (323 reviews)
"Wonderful place to stay!"
Canada
Kim
The price is RM1,147
RM1,309 total
includes taxes & fees
6 Apr - 7 Apr
Charme Hotel Henry's House

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (585 reviews)
"Great location and beautiful scenery "
United States
Yuqi
The price is RM1,149
RM1,311 total
includes taxes & fees
8 Apr - 9 Apr
Grand Hotel Ortigia Siracusa

Borgo Pantano

Borgo Pantano
4.0 star property
Syracuse
9.8 out of 10, Exceptional, (276 reviews)
"Beautiful property and excellent breakfast. Lived our stay! "
United States
Feldman
The price is RM515
RM588 total
includes taxes & fees
7 Apr - 8 Apr
Borgo Pantano
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Syracuse Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Syracuse?
Travel to Catania (CTA-Fontanarossa) Airport or Comiso (CIY-Vincenzo Magliocco) Airport, and then treat yourself to a stay at one of 11 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best luxury place to stay in Syracuse?
Grand Hotel Ortigia Siracusa is a luxury hotel with a private beach and spa services, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Ortea Palace Hotel, Sicily, Autograph Collection and Wellness & Spa Hotel Principe di Fitalia are other upscale choices for your trip.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 11 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for Syracuse is 653 mm.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To venture out into the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

Explore a world of travel with Expedia