Midtown
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Small Group Tour With Arch & River Cruise
Lemp Haunted Neighborhood Walking Tour
St Louis Self-Guided Driving and Walking Audio Tour
Top hotels in Midtown
Element St. Louis Midtown
Their team is extremely professional and very helpful. Place is maintained well, water is triple filtered, and the manager Joanne is fantastic. Thank you guys for helping us with our luggage fiasco, I would definitely come back again. The beds are extremely comfortable 10/10 recommend.
Reviewed on 30 Mar 2026
Residence Inn by Marriott St Louis Downtown
Great, convenient location. Rooms were nice and complimentary breakfast was great.
Reviewed on 31 Mar 2026
Drury Plaza Hotel St. Louis at the Arch
Great place, great service and definitely will be back. Oh, and the best coffee ever in the mornings!
Reviewed on 31 Mar 2026
Pear Tree Inn St. Louis Near Union Station
Staff could be friendly - the kick back left alot to desired, several times the nachos, cheese and toppings ran out and it took 10+ mins to refill. Soda machine was broken most of our stay. Bottom parking deck was closed and key cards wouldn't on top deck so you had to call for help which was another ...
Reviewed on 30 Mar 2026
Clayton Plaza Hotel & Extended Stay
I did not eat breakfast but it’s was an amazing stay.
Reviewed on 30 Mar 2026
21C Museum Hotel St Louis
We never got to check in lol. At 1830 they still has no rooms clean. Large line waiting. We just canceled and left 😩
Reviewed on 30 Mar 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Enterprise Center.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Enterprise Center are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Zoo and St. Louis Science Center.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
