𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 St. Charles from RM288 (2026) - Fully Refundable Options

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Our top choices for St. Charles hotels

Desk, blackout curtains, iron/ironing board, free cots/infant beds

1. AmericInn by Wyndham Winona

Winona

Jacob

RM552 total

includes taxes & fees

9 Aug - 10 Aug

In-room safe, desk, blackout curtains, iron/ironing board

2. Days Inn by Wyndham Winona

Winona

Twila

RM311 total

includes taxes & fees

17 Aug - 18 Aug

3. Spark by Hilton Rochester South

Rochester

Lijing

RM344 total

includes taxes & fees

2 Aug - 3 Aug

4. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

RM384 total

includes taxes & fees

2 Aug - 3 Aug

5. Hampton Inn Rochester-South

Rochester

Richard

RM439 total

includes taxes & fees

16 Aug - 17 Aug

6. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Laura

RM449 total

includes taxes & fees

20 Aug - 21 Aug

7. Stone Mill Hotel & Suites

Lanesboro

Allan

RM461 total

includes taxes & fees

2 Aug - 3 Aug

8. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

harold

RM377 total

includes taxes & fees

16 Aug - 17 Aug

9. The Wen Inn formerly Andor Wenneson

Peterson

jen

RM468 total

includes taxes & fees

27 Jul - 28 Jul

10. Fairfield Inn & Suites by Marriott Winona

Winona

Micaiah

RM613 total

includes taxes & fees

9 Aug - 10 Aug

Down duvets, pillow-top beds, blackout curtains, soundproofing

11. Country Trails Inn & Suites

Preston

Robert

RM571 total

includes taxes & fees

23 Jul - 24 Jul

12. Green Gables Inn

Lanesboro

Deborah

RM498 total

includes taxes & fees

19 Aug - 20 Aug

13. The Plaza Hotel & Suites Winona

Winona

James

RM685 total

includes taxes & fees

28 Jul - 29 Jul

14. Econo Lodge Mayo Clinic Area

Rochester

Daniel

RM324 total

includes taxes & fees

16 Aug - 17 Aug

Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers

15. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Rochester

Debora

RM443 total

includes taxes & fees

9 Aug - 10 Aug

16. Holiday Inn Express & Suites Winona by IHG

Winona

Kayla

RM663 total

includes taxes & fees

2 Aug - 3 Aug

17. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park

Brian

RM556 total

includes taxes & fees

21 Aug - 22 Aug

18. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

Julie

RM373 total

includes taxes & fees

9 Aug - 10 Aug

19. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

Charles

RM400 total

includes taxes & fees

7 Aug - 8 Aug

20. Alexander Mansion Bed and Breakfast

Historic Downtown Winona

Pamela

RM523 total

includes taxes & fees

30 Jul - 31 Jul

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Learn more about St. Charles

St. Charles awaits: its natural setting and more!

See all hotels in St. Charles

An aerial view of a town with industrial buildings, roads, and green areas.

Top St. Charles Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"Very welcoming and supportive on my Mayo Clinic trip."

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"The hotel rooms were bigger than expected and very clean. The hotel is in front of St Mary's hospital but a little farther from downtown than expected. Food at the hotel was limited and no close by places to eat. Staff was not helpful in identifying places to eat at downtown even though there are very good restaurants in the downtown area. Definitely will stay again at this location if my visit was closer to the St. Mary's hospital."

The Berkman

8/10 Good

"Wonderful property with a few caveats. The amenities are great, and the location is ideal for St Mary’s. The apartment is large and parking safe and easy. That said, the bed is very hard and pillows aren’t great. The vents also hit directly on your face in the bed, so that was hard to get used to. I would stay again but only if I brought my own pillows and blankets"

Big River Escape Riverside Cabins

10/10 Excellent

"Great experience. Traveling with my husband to visit the area and do hikes. Nice location and cozy cute cabins! Owner is super helpful and kind. Minor hiccup at check-in due to booking through Expedia - Expedia doesn't share any info with the owner of the property and the email for my self check-in wasn't sent. I called the owner and he called right back after a few minutes and was able to give me all the instructions I needed. He even gave me some hiking recommendations. Later, the water wasn't getting hot in our cabin. I texted the owner and he came to check things out right away. He informed us that sadly, the water heater was going to need repairs. He upgraded us to another cabin that was actually bigger and very nice - the one we were in was also so cozy and lovely. Thankfully, our stay was uneventful (in the best way) from there on out! Cabins are very clean, cozy and have everything you need to cook food if you choose! Not far away from nice hikes in Winona or Alma. Oh and it's near the water too with a dock if you're into that. 😁 Owner is extremely kind, accommodating and hospitable. Highly recommend."

More cheap stays in St. Charles

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN

RM254

RM288 total

2 Aug - 3 Aug

includes taxes & fees

7.8/10 Good! (1,011 reviews)

Frequently asked questions

Where is the best place to stay in St. Charles?

Kahler Grand Hotel, located 20.6 mi (33.1 km) from the heart of St. Charles, is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Kahler Inn and Suites - Mayo Clinic Area and Best Western Rochester Hotel Mayo Clinic Area/St. Mary's. See all available top hotels, or vacation rentals in St. Charles.

If I need to cancel my hotel reservation in St. Charles, will I receive a refund?

Yes! The majority of room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.

What's it like to stay in St. Charles?

Visitors can enjoy all that St. Charles has to offer, including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 3 hotels and other accommodation options to choose from. Find out more about St. Charles.

What is there to see in St. Charles?

A couple of favourite places to visit are Whitewater State Park and Whitewater River. You'll also find Regional Sports Center and National Volleyball Center in the area. Take a look at what more there is to see and do in Expedia's St. Charles guide.

What's the weather like in St. Charles?

The hottest months are usually July and August, with an average temperature of 19°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in St. Charles are January, March, February and April, with each month seeing an average of 20 cm of snowfall.

St. Charles hotels from RM288

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Our top choices for St. Charles hotels

1. AmericInn by Wyndham Winona

2. Days Inn by Wyndham Winona

3. Spark by Hilton Rochester South

4. Comfort Inn & Suites Rochester South Mayo Clinic

5. Hampton Inn Rochester-South

6. Holiday Inn Express Rochester South - Mayo Area by IHG

7. Stone Mill Hotel & Suites

8. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

9. The Wen Inn formerly Andor Wenneson

10. Fairfield Inn & Suites by Marriott Winona

11. Country Trails Inn & Suites

12. Green Gables Inn

13. The Plaza Hotel & Suites Winona

14. Econo Lodge Mayo Clinic Area

15. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

16. Holiday Inn Express & Suites Winona by IHG

17. TownePlace Suites by Marriott Rochester Mayo Clinic Area

18. AmericInn by Wyndham Rochester Near Mayo Clinic

19. Hotel Indigo Rochester – Mayo Clinic Area by IHG

20. Alexander Mansion Bed and Breakfast

Learn more about St. Charles

Top St. Charles Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

More cheap stays in St. Charles

Super 8 by Wyndham Winona MN

Frequently asked questions

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