Hotels in Serra Mesa, San Diego

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Our top choices for Serra Mesa hotels

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.4 out of 10, Exceptional, (1,884 reviews)
"Amazing rooms and casino "
United States
Bryan
The price is RM392
RM478 total
includes taxes & fees
4 May - 5 May
Sycuan Casino Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,505 reviews)
"Great stay and family friendly "
United States
Gregory
The price is RM671
RM972 total
includes taxes & fees
25 May - 26 May
Sheraton San Diego Resort

Ramada by Wyndham San Diego Poway Miramar

Ramada by Wyndham San Diego Poway Miramar
2.0 star property
18.2 km from Serra Mesa
7.0 out of 10, Good, (1,003 reviews)
"Quick to checking in nice staff and breakfast was good there was plenty of parking lot to park"
United States
Ruffa Regina
The price is RM373
RM411 total
includes taxes & fees
10 May - 11 May
Ramada by Wyndham San Diego Poway Miramar

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 7.2 km from Serra Mesa
8.4 out of 10, Very good, (1,431 reviews)
"Staff were very friendly and accommodating The resort was beautiful and location was amazing"
United States
Valerie
The price is RM870
RM1,210 total
includes taxes & fees
10 May - 11 May
San Diego Mission Bay Resort

Pleasant Inn

Pleasant Inn
2.5 star property
4.8 km from Serra Mesa
8.6 out of 10, Excellent, (1,383 reviews)
" Clean room friendly staff"
Canada
Laurent
The price is RM371
RM426 total
includes taxes & fees
12 May - 13 May
Pleasant Inn

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach, 10.7 km from Serra Mesa
8.6 out of 10, Excellent, (2,041 reviews)
"Family friendly with many onsite activities and near by dinning options "
United States
samantha
The price is RM675
RM997 total
includes taxes & fees
18 May - 19 May
Bahia Resort Hotel

Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego, 7.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,416 reviews)
"Friendly staff and decent place to stay "
United States
Dennis
The price is RM487
RM559 total
includes taxes & fees
10 May - 11 May
Hilton Garden Inn San Diego Old Town/SeaWorld Area

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
28.1 km from Serra Mesa
9.0 out of 10, Wonderful, (1,265 reviews)
"Clean room, nice staff, a simple breakfast, and free parking on site."
United States
Nicole
The price is RM486
RM552 total
includes taxes & fees
10 May - 11 May
Best Western Americana Inn

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,215 reviews)
"Room was clean hotel was close to beach & restaurant "
United States
Andrea
The price is RM433
RM498 total
includes taxes & fees
4 May - 5 May
Wyndham Garden San Diego Near SeaWorld

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
12.6 km from Serra Mesa
9.2 out of 10, Wonderful, (3,558 reviews)
"Great place and walking distance to many different places. Stayed before getting on a cruise."
United States
Lawrence
The price is RM604
RM694 total
includes taxes & fees
12 May - 13 May
Bay Club Hotel & Marina

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (2,062 reviews)
"Great hotel and in a great location "
United States
Danielle
The price is RM415
RM477 total
includes taxes & fees
10 May - 11 May
GreenTree Inn San Diego Mission Bay

Ash&9th

Ash&9th
2.0 star property
9.4 km from Serra Mesa
8.2 out of 10, Very good, (573 reviews)
"Great location, reasonable parking, comfortable beds and pleasant staff"
United States
Sharon
The price is RM393
RM447 total
includes taxes & fees
12 May - 13 May
Ash&9th

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 7.9 km from Serra Mesa
8.2 out of 10, Very good, (2,017 reviews)
"Great location. "
Mexico
Ramon Andres
The price is RM419
RM482 total
includes taxes & fees
10 May - 11 May
Comfort Inn San Diego Old Town

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 9.9 km from Serra Mesa
8.8 out of 10, Excellent, (2,563 reviews)
"Everything in the hotel is especial recommend 100% amazing place familiar, best place for relaxing "
United States
Rolando
The price is RM826
RM1,160 total
includes taxes & fees
10 May - 11 May
Paradise Point Resort & Spa

Ocean Beach Hotel

Ocean Beach Hotel
3.0 star property
Ocean Beach, 12.3 km from Serra Mesa
8.8 out of 10, Excellent, (1,331 reviews)
"Excellent location"
United States
Hyo seon
The price is RM715
RM806 total
includes taxes & fees
5 May - 6 May
Ocean Beach Hotel

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
7.9 km from Serra Mesa
9.0 out of 10, Wonderful, (1,055 reviews)
"It was clean and convenient to the airport."
United States
Joey L
The price is RM560
RM644 total
includes taxes & fees
10 May - 11 May
Holiday Inn Express San Diego Airport - Old Town by IHG

The Beau Hotel Gaslamp Quarter San Diego

The Beau Hotel Gaslamp Quarter San Diego
3.0 star property
Gaslamp Quarter, 9.9 km from Serra Mesa
9.0 out of 10, Wonderful, (711 reviews)
"Nice bar/restaurant, clean rooms, very nice hotel"
United States
Juan
The price is RM593
RM675 total
includes taxes & fees
5 May - 6 May
The Beau Hotel Gaslamp Quarter San Diego

Best Western San Diego/Miramar Hotel

Best Western San Diego/Miramar Hotel
2.5 star property
10.1 km from Serra Mesa
7.8 out of 10, Good, (1,309 reviews)
"Best hotel and the location "
United States
Mercy
The price is RM417
RM479 total
includes taxes & fees
3 May - 4 May
Best Western San Diego/Miramar Hotel

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
6 km from Serra Mesa
8.8 out of 10, Excellent, (3,684 reviews)
"We had a great stay! The room was super clean, parking was easy, and it was in a good location."
United States
Charlene
The price is RM326
RM374 total
includes taxes & fees
3 May - 4 May
Kings Inn San Diego

Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town
3.0 star property
Old Town San Diego, 7.6 km from Serra Mesa
8.4 out of 10, Very good, (1,985 reviews)
"Good location and staff was great "
United States
Javier
The price is RM497
RM571 total
includes taxes & fees
10 May - 11 May
Best Western Plus Hacienda Hotel Old Town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most. Learn more about Serra Mesa
Learn more about Serra Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 38 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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