Hotels in Serra Mesa, San Diego

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11 Oct - 12 Oct
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12 Oct - 13 Oct
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17 Oct - 19 Oct
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24 Oct - 26 Oct

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Top 10 Hotels in Serra Mesa, San Diego

Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very good, (5996)
"Enjoyed our stay very much."
The price is RM643
RM867 total
includes taxes & fees
14 Oct - 15 Oct
Wyndham San Diego Bayside
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (3006)
"Great stay"
The price is RM870
RM1,203 total
includes taxes & fees
20 Oct - 21 Oct
Hard Rock Hotel San Diego
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Exterior

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
9.0 out of 10, Wonderful, (1160)
"Clean room ,friendly staff, great location "
The price is RM607
RM704 total
includes taxes & fees
13 Oct - 14 Oct
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Outdoor pool

Ramada Suites by Wyndham San Diego/Hotel Circle Area

2.5 star property
6.2 out of 10, (1025)
"Clean room, friendly staff"
The price is RM316
RM363 total
includes taxes & fees
27 Oct - 28 Oct
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Best Western Plus Marina Gateway Hotel
Premium bedding, in-room safe, desk, laptop workspace

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3322)
"Nice place to stay !"
The price is RM566
RM624 total
includes taxes & fees
2 Nov - 3 Nov
Best Western Plus Marina Gateway Hotel
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1012)
"Had a great stay "
The price is RM456
RM519 total
includes taxes & fees
13 Oct - 14 Oct
Gaslamp Plaza Suites
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2596)
"Great location and friendly staff"
The Horton Grand, Downtown/Gaslamp Quarter
El Cordova Hotel on Coronado Island
Lobby

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1006)
"Cute and unique hotel！"
The price is RM966
RM1,191 total
includes taxes & fees
6 Nov - 7 Nov
El Cordova Hotel on Coronado Island
Best Western Plus Suites Hotel Coronado Island
Outdoor pool, pool loungers

Best Western Plus Suites Hotel Coronado Island

2.5 star property
8.8 out of 10, Excellent, (1009)
"Great staff and breakfast "
The price is RM697
RM774 total
includes taxes & fees
26 Oct - 27 Oct
Best Western Plus Suites Hotel Coronado Island
La Pensione Hotel
Exterior

La Pensione Hotel

3.0 star property
8.6 out of 10, Excellent, (1882)
"Very happy with our stay "
La Pensione Hotel
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillow-top beds, desk, blackout curtains

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Great staff and clean rooms"
The price is RM628
RM850 total
includes taxes & fees
29 Oct - 30 Oct
Staypineapple, Hotel Z, Gaslamp San Diego
Days Inn by Wyndham San Diego-East/El Cajon
Desk, laptop workspace, iron/ironing board, free WiFi

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1008)
"Place was nice and comfy. Decent stay at a very genuine price. "
The price is RM341
RM375 total
includes taxes & fees
19 Oct - 20 Oct
Days Inn by Wyndham San Diego-East/El Cajon
The Dana on Mission Bay
2 outdoor pools, a heated pool, pool loungers

The Dana on Mission Bay

3.5 star property
8.8 out of 10, Excellent, (3780)
"Great stay"
The price is RM571
RM740 total
includes taxes & fees
21 Oct - 22 Oct
The Dana on Mission Bay
Days Inn by Wyndham San Diego Hotel Circle
Outdoor pool, a heated pool

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
8.0 out of 10, Very good, (2367)
"We loved our stay, great price, very clean and excellent location! "
The price is RM414
RM476 total
includes taxes & fees
13 Oct - 14 Oct
Days Inn by Wyndham San Diego Hotel Circle
Ramada by Wyndham San Diego Poway Miramar
Exterior

Ramada by Wyndham San Diego Poway Miramar

2.0 star property
7.0 out of 10, Good, (893)
"The king room was clean & cozy with a nice stand up shower. My stay was comfortable, wish I would have booked more nights. "
The price is RM369
RM406 total
includes taxes & fees
13 Oct - 14 Oct
Ramada by Wyndham San Diego Poway Miramar
Bay Club Hotel & Marina
Exterior

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (3008)
"Great location, friendly staff, very clean accommodations and spacious rooms "
The price is RM524
RM603 total
includes taxes & fees
28 Oct - 29 Oct
Bay Club Hotel & Marina
Urban Boutique Hotel
Check-in/check-out kiosk

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1259)
"Great location, clean rooms, really nice continental breakfast and very nice staff😊"
The price is RM481
RM548 total
includes taxes & fees
13 Oct - 14 Oct
Urban Boutique Hotel
Sycuan Casino Resort
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1567)
"Great resort!"
Sycuan Casino Resort
Hotel Palmeras Chula Vista
Front of property

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1891)
"Quiet area all around nice place to stay !!!"
The price is RM304
RM335 total
includes taxes & fees
2 Nov - 3 Nov
Hotel Palmeras Chula Vista
La Quinta Inn by Wyndham San Diego - Miramar
Reception

La Quinta Inn by Wyndham San Diego - Miramar

3.0 star property
7.6 out of 10, Good, (1038)
"Staff was friendly and very inviting. Would definitely stay here again. "
The price is RM376
RM432 total
includes taxes & fees
19 Oct - 20 Oct
La Quinta Inn by Wyndham San Diego - Miramar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most. Learn more about Serra Mesa
Learn more about Serra Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter showing night scenes, a bar and street scenes

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park showing a sandy beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park showing rides and a park

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

The Sofia Hotel

The Sofia Hotel

10/10 Excellent
"The Sophia is a wonderful property near all areas we enjoy."
Sheila 5-night trip
Posted 13 hours ago
The Sofia Hotel

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Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 35 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.