Best Luxury Hotels in Santo Antonio

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Check availability on Santo Antonio Luxury Hotels

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Santo Antonio luxury hotels

Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1000)
"We were lucky enough to stay at the hotel twice and found the staff really helpful the rooms spotless and the ambience terrific. "
United Kingdom
Peter
The price is RM916
RM1,009 total
includes taxes & fees
25 Jan - 26 Jan 2026
EPIC SANA Lisboa Hotel
Exterior
PortoBay Liberdade

PortoBay Liberdade

PortoBay Liberdade
5.0 star property
Lisbon City Center
9.4 out of 10, Exceptional, (1001)
"fantastic stay everyone was very nice and friendly"
United States
Radovan
The price is RM670
RM748 total
includes taxes & fees
5 Jan - 6 Jan 2026
PortoBay Liberdade
Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, pool loungers
Valverde Lisboa Hotel & Garden - Relais & Châteaux

Valverde Lisboa Hotel & Garden - Relais & Châteaux

Valverde Lisboa Hotel & Garden - Relais & Châteaux
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (497)
"Excellent staff and wonderful stay all around."
United States
Donald
The price is RM2,158
RM2,326 total
includes taxes & fees
5 Jan - 6 Jan 2026
Valverde Lisboa Hotel & Garden - Relais & Châteaux
Exterior
Sofitel Lisbon Liberdade

Sofitel Lisbon Liberdade

Sofitel Lisbon Liberdade
5.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1001)
"Friendly staff!"
United States
Caroline
The price is RM836
RM925 total
includes taxes & fees
11 Jan - 12 Jan 2026
Sofitel Lisbon Liberdade
Daily buffet breakfast (EUR 31 per person)
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
5.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1001)
"Room and bathroom were stylish, clean and very comfortable. Staff was very nice. The doorman was very friendly and helpful."
United States
Alicia
The price is RM1,425
RM1,549 total
includes taxes & fees
21 Jan - 22 Jan 2026
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
Minibar, in-room safe, desk, blackout curtains
Altis Grand Hotel

Altis Grand Hotel

Altis Grand Hotel
5.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (1003)
"wonderful hotel and best service. "
United States
Jiemin
The price is RM520
RM590 total
includes taxes & fees
8 Jan - 9 Jan 2026
Altis Grand Hotel
Daily buffet breakfast (EUR 20 per person)
The Vintage Hotel & Spa - Lisbon

The Vintage Hotel & Spa - Lisbon

The Vintage Hotel & Spa - Lisbon
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (326)
"great holiday venue.great staff.great food"
United Kingdom
John
The Vintage Hotel & Spa - Lisbon
Serves lunch and dinner
Eurostars Das Letras

Eurostars Das Letras

Eurostars Das Letras
5.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1003)
"I enjoyed my stay at this hotel. The staff has great service and the rooms were very comfortable. "
United States
Sharlene
The price is RM441
RM506 total
includes taxes & fees
25 Jan - 26 Jan 2026
Eurostars Das Letras
Exterior
138 Liberdade Hotel

138 Liberdade Hotel

138 Liberdade Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (647)
"Tidy room, lovely breakfast, helpful staff and a very nice smelling hotel."
United Kingdom
Craig
The price is RM810
RM897 total
includes taxes & fees
18 Jan - 19 Jan 2026
138 Liberdade Hotel
Hallway
Hotel Britania Art Deco, a Lisbon Heritage Collection

Hotel Britania Art Deco, a Lisbon Heritage Collection

Hotel Britania Art Deco, a Lisbon Heritage Collection
4.0 star property
Lisbon City Center
9.8 out of 10, Exceptional, (1003)
"Great staff , room was amazing . Great location "
United Kingdom
James
The price is RM631
RM707 total
includes taxes & fees
15 Jan - 16 Jan 2026
Hotel Britania Art Deco, a Lisbon Heritage Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Antonio Hotel Reviews

HF Fénix Lisboa

HF Fénix Lisboa

10/10 Excellent
"Nice hotel, friendly staff, clean and comfortable. Great location an the best breakfast. "
Paola Lara 2-night trip
Posted 5 days ago
HF Fénix Lisboa

Frequently asked questions

Are you looking for a luxury hotel for your Santo Antonio holiday?
Travel to Lisbon (LIS-Humberto Delgado) Airport or Cascais (CAT) Airport, and then treat yourself to a stay at one of 17 Santo Antonio luxury hotels. Known for its spas and art, Santo Antonio also has some interesting things to see and do including Avenida da Liberdade, so you may want to take in the local sights during your visit.
What's the best luxury hotel in Santo Antonio?
EPIC SANA Marques Hotel is a luxury hotel with 2 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Altis Grand Hotel and Browns Avenue Hotel are other upscale choices for your holiday.
How many luxury hotels should I expect to find in Santo Antonio?
Lie in the lap of luxury during your getaway to Santo Antonio in one of Expedia's 17 luxury hotels.
When can I expect good weather in Santo Antonio?
Planning for the weather is an important factor for making your trip to Santo Antonio a success, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 21°C, while the coldest months are February and January, with an average of 13°C. Average annual precipitation for Santo Antonio is 573 mm.
What's there to see and do in Santo Antonio?
When you're in Santo Antonio, enjoy exploring the sights and attractions here including Avenida da Liberdade, Marquis of Pombal Square and Torel Garden. If you have extra time while you're in the area, you might want to stop by Medeiros e Almeida Museum and Cinemateca Portuguesa Museum.
How can I get around Santo Antonio?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including Avenida Station, Marques de Pombal Station and Rato Station.