Hotels in Santa Lucia, Syracuse

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in Santa Lucia, Syracuse

Grande Albergo Alfeo

4.0 star property
8.6 out of 10, Excellent, (642)
"The hotel is very central in the main town of Siracusa. Plenty of good restaurants on the doorstep and only ten minute walk from the station. Ortigia only a 15 minute walk away. The bathroom facilities and room decor are slightly old fashioned but all working fine. "
Grande Albergo Alfeo

Caportigia Boutique Hotel

5.0 star property
9.4 out of 10, Exceptional, (248)
"Great base for exploring Syracuse. "
The price is RM876
RM1,013 total
includes taxes & fees
26 Oct - 27 Oct
Caportigia Boutique Hotel

Hotel Palazzo Cavalieri

4.0 star property
9.0 out of 10, Wonderful, (32)
"Enjoyed our stay, nice comfortable room and bed. Very nice breakfast buffet. Within a quick 5 min walk to Ortigia Island, also walkable to train and bus station. Would stay here again."
Hotel Palazzo Cavalieri

Lakkios

3.0 star property
9.0 out of 10, Wonderful, (56)
"Nice location to where dining options and sites to see are numerous "
Lakkios

B&B Nike

9.0 out of 10, Wonderful, (69)
"This is an AMAZING AND EXCEPTIONAL property! Tucked away in a residential area with just a three minute walk to the bus stop. The hotel is beautifully furnished and modern. The rooms are spacious and inviting. This boutique hotel feels like a luxury five star hotel. I definitely want to come back to Cagliari, and when I do, rest assured I will be staying at Nemo. Also breakfast on the roof top is amazing! "
B&B Nike

Fortaleza Charme House

10.0 out of 10, Exceptional, (22)
"Lovely hotel, very friendly service, huge rooms. "
The price is RM683
RM779 total
includes taxes & fees
13 Oct - 14 Oct
Fortaleza Charme House

San Nicola Rooms Siracusa

9.0 out of 10, Wonderful, (2)
"Não se espante com o prédio onde está localizado o hotel (fica no terceiro andar). Os quartos são novos e muito confortáveis. E ficar atento porque não há estacionamento grátis, mas sim pago na rua. "
The price is RM517
RM590 total
includes taxes & fees
12 Oct - 13 Oct
San Nicola Rooms Siracusa

Siracusa Resort Musciara

3.0 star property
9.6 out of 10, Exceptional, (37)
"Very clean, lovely hotel with a wide variety of room choices. The dining area is on the water - very nice place to eat a meal. The beach is fantastic! It's an easy walk into old town Ortigia. Convenient parking lot next door."
The price is RM1,751
RM1,975 total
includes taxes & fees
5 Oct - 6 Oct
Siracusa Resort Musciara

B&B Triskeles

3.0 star property
8.2 out of 10, Very good, (57)
"Excellent stay, close to everything and easy parking"
The price is RM292
RM333 total
includes taxes & fees
10 Oct - 11 Oct
B&B Triskeles

Casa Miranda Boutique

The price is RM930
RM1,060 total
includes taxes & fees
12 Oct - 13 Oct
Casa Miranda Boutique

Giuggiulena Villa

3.0 star property
10.0 out of 10, Exceptional, (125)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
Giuggiulena Villa

Hotel Le Muse

3.0 star property
7.4 out of 10, Good, (66)
"The room was great and the staff was exceptionally helpful"
The price is RM549
RM626 total
includes taxes & fees
29 Sept - 30 Sept
Hotel Le Muse

Re Dionisio Luxury Suites

3.0 star property
8.8 out of 10, Excellent, (54)
"Wonderful property, excellent staff and the most amazing view from the apartment"
The price is RM1,416
RM1,607 total
includes taxes & fees
1 Oct - 2 Oct
Re Dionisio Luxury Suites

Nostos rooms & Apartments

3.0 star property
9.0 out of 10, Wonderful, (266)
"On a main thoroughfare close to Isola di Ortigia. Friendly management and helpful to me."
The price is RM368
RM420 total
includes taxes & fees
21 Oct - 22 Oct
Nostos rooms & Apartments

Gymnasium

3.0 star property
9.0 out of 10, Wonderful, (37)
"Great location, clean new comfortable room and kitt. "
Gymnasium

Hotel dei Coloniali

3.0 star property
7.4 out of 10, Good, (164)
"Convenient location for Syracuse town, but in a scruffy area and the whole property is looking tired. Breakfast was adequate. The owner was charming and happy to help."
The price is RM359
RM410 total
includes taxes & fees
12 Oct - 13 Oct
Hotel dei Coloniali

Piccolo Hotel Casa Mia

3.0 star property
8.6 out of 10, Excellent, (369)
"Nice quirky place to stay in Siracusa located conveniently for everything you need and very professional staff "
Piccolo Hotel Casa Mia

Hotel Mediterraneo

3.0 star property
7.8 out of 10, Good, (121)
"Nice clean room, pleasant staff, great location."
Hotel Mediterraneo

Populus

1.0 star property
7.8 out of 10, Good, (73)
"Just stay somewhere else, plain and simple."
The price is RM364
RM464 total
includes taxes & fees
12 Oct - 13 Oct
Populus

AmaCasa Siracusa

10.0 out of 10, Exceptional, (1)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
The price is RM404
RM461 total
includes taxes & fees
12 Oct - 13 Oct
AmaCasa Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Top Santa Lucia Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Lucia?

Based on Expedia customer reviews, Fortaleza Charme House is the highest ranked property in Santa Lucia. This inn is a short 6-minute walk from Lungomare di Ortigia, and it offers a beach bar and free WiFi. Other top choices in the neighbourhood include Caportigia Boutique Hotel and Nostos rooms & Apartments.

How many hotels will I find in Santa Lucia?

Expedia has 271 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.