A calm body of water with a tree branch in the foreground and a dense green shoreline in the background.

Hotels near Sanibel Bayous

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Sanibel Bayous hotels

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

1. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
20.9 km from Sanibel Bayous
9.4 out of 10, Exceptional, (1,730 reviews)
"Excellent hotel if you want to stay there for a few days"
United States
Gabriel
The price is RM409
RM456 total
includes taxes & fees
2 Nov - 3 Nov
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

2. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
17.3 km from Sanibel Bayous
9.0 out of 10, Wonderful, (1,000 reviews)
"I like this hotel we have been twice"
United States
Giovanna
The price is RM404
RM450 total
includes taxes & fees
2 Nov - 3 Nov
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

3. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
18.8 km from Sanibel Bayous
8.8 out of 10, Excellent, (1,007 reviews)
"One of the best properties I’ve stayed in and the staff were excellent."
United States
Christina
The price is RM371
RM414 total
includes taxes & fees
31 Oct - 1 Nov
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

4. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
15.9 km from Sanibel Bayous
8.2 out of 10, Very good, (1,396 reviews)
"The staff was very helpful during my stay."
United States
Samantha
The price is RM342
RM382 total
includes taxes & fees
4 Nov - 5 Nov
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A balcony with a table and chairs, large windows, and a view of the sea.

5. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
15.1 km from Sanibel Bayous
9.0 out of 10, Wonderful, (1,000 reviews)
"Very clean and nice place!"
United States
Charles
The price is RM596
RM847 total
includes taxes & fees
29 Nov - 30 Nov
The Westin Cape Coral Resort At Marina Village
A beach with a variety of seashells and pebbles.

6. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 8.5 km from Sanibel Bayous
9.2 out of 10, Wonderful, (2,385 reviews)
"Love this place - always have a nice time here -"
United States
Pablo
The price is RM811
RM1,018 total
includes taxes & fees
3 Nov - 4 Nov
Sanibel Island Beach Resort
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

7. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
15.2 km from Sanibel Bayous
8.8 out of 10, Excellent, (1,000 reviews)
"The hotel was in a great location, very clean and had great breakfast options."
United States
jennifer
The price is RM367
RM409 total
includes taxes & fees
1 Nov - 2 Nov
Residence Inn by Marriott Fort Myers Sanibel
A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.

8. Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
20.1 km from Sanibel Bayous
9.6 out of 10, Exceptional, (304 reviews)
"The place was perfect for what we needed for this trip."
United States
Francisco
The price is RM306
RM636 total
includes taxes & fees
30 Oct - 31 Oct
Matlacha on Shoreview
A modern living room with a flat-screen TV, a floor lamp, a dining table, and a sofa.

9. Lazy Cuckoo Inn

Lazy Cuckoo Inn
2.0 star property
18.1 km from Sanibel Bayous
8.8 out of 10, Excellent, (304 reviews)
"Great place!"
United States
Bruce
The price is RM237
RM397 total
includes taxes & fees
2 Nov - 3 Nov
Lazy Cuckoo Inn
Living area

10. The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 8.2 km from Sanibel Bayous
10.0 out of 10, Exceptional, (82 reviews)
"The whole place was wonderful."
United States
April
The price is RM681
RM820 total
includes taxes & fees
12 Nov - 13 Nov
The Anchor Inn
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

11. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
19 km from Sanibel Bayous
9.2 out of 10, Wonderful, (1,001 reviews)
"Clean Hotel! Convenient for one night stay, close to airport and beaches."
United States
Kimberly
The price is RM379
RM423 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
An outdoor seating area with tables and chairs, surrounded by palm trees and a thatched-roof structure.

12. Dolphin Key Resort

Dolphin Key Resort
3.0 star property
20.7 km from Sanibel Bayous
8.8 out of 10, Excellent, (1,163 reviews)
"The staff is incredibly friendly and the location is central to all the cities fun places to visit."
United States
DANIEL
The price is RM384
RM429 total
includes taxes & fees
22 Nov - 23 Nov
Dolphin Key Resort
A modern hotel lobby with a seating area, a reception desk, and a dining area.

13. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
19.7 km from Sanibel Bayous
8.8 out of 10, Excellent, (1,000 reviews)
"Such a great experience with friendly staff and very clean and comfortable!"
United States
Michael
The price is RM405
RM452 total
includes taxes & fees
12 Nov - 13 Nov
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

14. Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
16.5 km from Sanibel Bayous
9.4 out of 10, Exceptional, (1,006 reviews)
"Convenient location, friendly staff and clean rooms."
United States
Stacy
The price is RM883
RM985 total
includes taxes & fees
15 Nov - 16 Nov
Best Western Plus Beach Resort
A beach view from a balcony with a pool, palm trees, and a building with a balcony.

15. Edison Beach House

Edison Beach House
3.5 star property
16.7 km from Sanibel Bayous
9.4 out of 10, Exceptional, (1,957 reviews)
"One of the best locations on Ft Myers Beach"
United States
mark
The price is RM795
RM1,046 total
includes taxes & fees
5 Nov - 6 Nov
Edison Beach House
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

16. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
11.6 km from Sanibel Bayous
8.6 out of 10, Excellent, (1,000 reviews)
"I love everything about this hotel"
United States
Yunior
The price is RM845
RM1,085 total
includes taxes & fees
11 Nov - 12 Nov
Marriott Sanibel Harbour Resort & Spa
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

17. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
16 km from Sanibel Bayous
9.4 out of 10, Exceptional, (1,485 reviews)
"It's nice place to stay"
United States
Mario
The price is RM877
RM1,246 total
includes taxes & fees
15 Nov - 16 Nov
Pink Shell Beach Resort and Marina
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

18. Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Ybel, 7.2 km from Sanibel Bayous
8.8 out of 10, Excellent, (471 reviews)
"Hotel was amazing!!"
United States
Yesenia
The price is RM1,057
RM1,179 total
includes taxes & fees
30 Oct - 31 Oct
Casa Ybel Resort
A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

19. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
5.9 km from Sanibel Bayous
9.6 out of 10, Exceptional, (164 reviews)
"Very comfortable and convenient location!"
United States
Lisa
The price is RM732
RM952 total
includes taxes & fees
9 Nov - 10 Nov
Off the Charts Inn & Out Island Resort
A large, clear swimming pool with multiple lounge areas and palm trees.

20. Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
17.1 km from Sanibel Bayous
9.0 out of 10, Wonderful, (2,712 reviews)
"Our favorite place to stay."
United States
Anastasia
The price is RM730
RM1,019 total
includes taxes & fees
1 Nov - 2 Nov
Margaritaville Beach Resort Fort Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Sanibel Bayous

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
9.4
Exceptional
1,730 reviews
View
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
9.0
Wonderful
1,000 reviews
View
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
8.8
Excellent
1,007 reviews
View
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
8.2
Very good
1,396 reviews
View
A balcony with a table and chairs, large windows, and a view of the sea.
The Westin Cape Coral Resort At Marina Village
4.0 star property
9.0
Wonderful
1,000 reviews
View

Top Sanibel Bayous Hotel Reviews

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

10/10 Excellent
"They could do better on the food for breakfast at the restaurant on the property"
Carol 2-night trip
Posted 2 hours ago
Tween Waters Island Resort & Spa

Other attractions near Sanibel Bayous

A sunset over the ocean with waves, a bird flying, and a partly cloudy sky.

Sanibel Island Southern Beach

9.4/10 (1,097 reviews)
Why not spend a lazy afternoon at Sanibel Island Southern Beach during your trip to Sanibel?
See properties

Frequently asked questions

What's the area like around Sanibel Bayous?
Sanibel Bayous is located in Sanibel. You'll find 683 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay close to Sanibel Bayous?
Island Inn is one of the top choices for your stay based on our traveller data, and this aparthotel offers a private beach and free parking. It's located 3.4 mi (5.4 km) from Sanibel Bayous. Other good options within a few miles include Shalimar Beach Resort and Off the Charts Inn & Out Island Resort.
How many hotels will I be able to find close to Sanibel Bayous?
Expedia has 683 hotels and other accommodation options a few miles from Sanibel Bayous.
If I need to cancel the hotel reservation for my stay near Sanibel Bayous, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the "fully refundable" filter to get the best deals near Sanibel Bayous.
What can I see and do near Sanibel Bayous?
You'll want to browse the exhibits at Bailey - Matthews Shell Museum and Sanibel Historical Museum and Village. You can enjoy live performances at BIG Arts Center and Herb Strauss Schoolhouse Theater. Enjoy a stroll along the shore at Bowman's Beach, Sanibel Island Southern Beach and Blind Pass Beach.