Hotels in San Francisco, Panama City

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Our top choices for San Francisco hotels

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,006 reviews)
"Beautiful hotel, great service. Breakfast buffet is amazing. "
United States
Tamara
The price is RM1,127
RM1,240 total
includes taxes & fees
9 Mar - 10 Mar
JW Marriott Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,001 reviews)
"Good locatiion"
United States
Caren
The price is RM523
RM575 total
includes taxes & fees
8 Mar - 9 Mar
Sheraton Grand Panama

Comfortable 2BR City Apartment

Comfortable 2BR City Apartment
2.0 star property
San Francisco
The price is RM675
RM742 total
includes taxes & fees
19 Feb - 20 Feb
Comfortable 2BR City Apartment

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,419 reviews)
"Clean room,helpful staff around the hotel,good food options"
United States
Umar
The price is RM961
RM1,057 total
includes taxes & fees
9 Mar - 10 Mar
Megapolis Hotel Panamá

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,143 reviews)
"Hotel was very clean, the staff was very helpful and the breakfast was very good!"
United States
Monty
The price is RM421
RM463 total
includes taxes & fees
12 Mar - 13 Mar
Plaza Paitilla Inn Hotel

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (959 reviews)
"Perfect stay for a few days at Panama!"
United States
Maria
The price is RM463
RM510 total
includes taxes & fees
27 Feb - 28 Feb
Aloft Panama

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,036 reviews)
"excellent room and location"
United States
Jon
The price is RM673
RM740 total
includes taxes & fees
25 Feb - 26 Feb
Las Americas Golden Tower Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,154 reviews)
"Clean, nice staff and super close to the airport "
United States
Leticia
The price is RM408
RM449 total
includes taxes & fees
28 Feb - 1 Mar
Ramada Plaza by Wyndham Panama Punta Pacifica

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
"Overall stay was great..staff was super friendly"
United States
Bjorna
The price is RM461
RM507 total
includes taxes & fees
14 Mar - 15 Mar
Courtyard by Marriott Panama Multiplaza Mall

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (2 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is RM772
RM1,446 total
includes taxes & fees
19 Mar - 20 Mar
Wanders Panama by Boutique Apartments

ESHEL SUITES PANAMA

ESHEL SUITES PANAMA
2.5 star property
San Francisco
10.0 out of 10, Exceptional, (5 reviews)
"Loved the property and the location, it was clean , nice and I really enjoyed my stay there"
United States
Aron
The price is RM390
RM527 total
includes taxes & fees
28 Feb - 1 Mar
ESHEL SUITES PANAMA

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,558 reviews)
"Nice comfortable hotel and very friendly staff."
Canada
norah
The price is RM452
RM497 total
includes taxes & fees
19 Feb - 20 Feb
Decapolis Hotel Panama City

Dovle 510 in Ciudad de Panam

Dovle 510 in Ciudad de Panam
2.0 star property
San Francisco
The price is RM495
RM544 total
includes taxes & fees
27 Feb - 28 Feb
Dovle 510 in Ciudad de Panam

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (169 reviews)
"Clean room good place to stay "
United States
Gideon
The price is RM286
RM861 total
includes taxes & fees
22 Feb - 23 Feb
Boutique Apartments Panamá Coco del Mar

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (571 reviews)
"Great location, friendly staff, clean rooms, very comfortable beds. "
United States
Sharna
The price is RM627
RM689 total
includes taxes & fees
21 Mar - 22 Mar
Residence Inn by Marriott Panama City

Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
6.6 out of 10, (8 reviews)
"For me was very convenient "
United States
Natalia
The price is RM229
RM252 total
includes taxes & fees
19 Feb - 20 Feb
Casa Orquídea

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (30 reviews)
"The place was clean nice an its comfortable an the view is to kill for amazing ‼️"
United States
Odaine
Boutique Apartments Atlapa

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
Living 73 Panamá by Boutique Apartments

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
2.8 out of 10, (3 reviews)
"Inadequate heating in the pool , poor customer service. No hot water in the shower. It was a terrible experience but it’s a nice place, hopefully with better management can offer outstanding services "
United States
Herbert
The price is RM640
RM704 total
includes taxes & fees
19 Feb - 20 Feb
Dovle Residences by HMS-Preferred Member

Dovle 312 in Ciudad de Panam

Dovle 312 in Ciudad de Panam
2.0 star property
San Francisco
The price is RM675
RM742 total
includes taxes & fees
22 Feb - 23 Feb
Dovle 312 in Ciudad de Panam
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in San Francisco

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
ESHEL SUITES PANAMA
2.5 star property
10.0
Exceptional
5 reviews
View
Breakfast, lunch, dinner served; international cuisine
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6
Exceptional
1,154 reviews
View
Exterior
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
9.0
Wonderful
1,002 reviews
View
Daily buffet breakfast (PAB 21 per person)
Sheraton Grand Panama
4.0 star property
8.6
Excellent
1,001 reviews
View
4 outdoor pools, free pool cabanas, pool umbrellas
JW Marriott Panama
5.0 star property
9.0
Wonderful
1,006 reviews
View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Multicentro Panama and Avenida Balboa while you're in town.

Top San Francisco Hotel Reviews

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Looking for sights you might find in a travel guide about San Francisco? Consider a visit to Multiplaza Pacific Mall while you're in the neighbourhood.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 230 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Multicentro Panama might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Pacific Center. When you're sightseeing in Panama City, Soho City Center and National Shrine of the Heart of Mary are also worth a stop.