Top 10 Penrose Hotels of 2026

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Our top choices for Penrose hotels

1. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 6.5 km from Penrose

Greg

RM661 total

includes taxes & fees

5 Oct - 6 Oct

2. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4.4 km from Penrose

Arturo

RM603 total

includes taxes & fees

2 Oct - 3 Oct

3. Drury Plaza Hotel St. Louis Union Station

Downtown West, 6.1 km from Penrose

Katy

RM649 total

includes taxes & fees

13 Sept - 14 Sept

4. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 5.5 km from Penrose

paullita jeanne

RM736 total

includes taxes & fees

27 Sept - 28 Sept

5. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 5.8 km from Penrose

Erik

RM603 total

includes taxes & fees

4 Oct - 5 Oct

6. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 7.3 km from Penrose

Salvatore

RM639 total

includes taxes & fees

4 Oct - 5 Oct

7. Aloft by Marriott St Louis Central West End

Central West End, 4.8 km from Penrose

Changsuk

RM539 total

includes taxes & fees

20 Sept - 21 Sept

8. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 4.4 km from Penrose

Lyn

RM888 total

includes taxes & fees

4 Oct - 5 Oct

9. Pear Tree Inn St. Louis Near Union Station

Downtown West, 5.8 km from Penrose

LaSonia

RM553 total

includes taxes & fees

20 Sept - 21 Sept

10. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 6.7 km from Penrose

Eloise

RM588 total

includes taxes & fees

20 Sept - 21 Sept

11. Moonrise Hotel

5.8 km from Penrose

Nicole

RM718 total

includes taxes & fees

9 Sept - 10 Sept

12. Hotel Indigo St Louis - Central West End by IHG

Central West End, 4.3 km from Penrose

Simon

RM712 total

includes taxes & fees

20 Sept - 21 Sept

13. Drury Inn & Suites St. Louis Forest Park

8 km from Penrose

Jennifer

RM705 total

includes taxes & fees

13 Sept - 14 Sept

14. DoubleTree by Hilton St. Louis Forest Park

Central West End, 4.8 km from Penrose

Kevin

RM794 total

includes taxes & fees

20 Sept - 21 Sept

15. AC Hotel St. Louis Central West End

Central West End, 4.3 km from Penrose

chris

RM744 total

includes taxes & fees

27 Sept - 28 Sept

16. Home2 Suites by Hilton St. Louis Downtown

Downtown West, 6.3 km from Penrose

kaila

RM462 total

includes taxes & fees

18 Sept - 19 Sept

17. Hyatt Select St. Louis Airport

12 km from Penrose

Paige

RM547 total

includes taxes & fees

27 Sept - 28 Sept

18. Courtyard by Marriott St. Louis Downtown/Convention Center

Downtown St. Louis, 6.6 km from Penrose

Penny

RM507 total

includes taxes & fees

4 Oct - 5 Oct

19. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 7.3 km from Penrose

TRACY

RM725 total

includes taxes & fees

4 Oct - 5 Oct

20. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 7 km from Penrose

Crystal

RM578 total

includes taxes & fees

14 Sept - 15 Sept

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Where to stay in Penrose

Find the best Penrose areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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A historic brick building with arched doorways and a sign that reads "Hot Goods Pen House."

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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Top Penrose Hotel Reviews

Hollywood Casino & Hotel St. Louis

8/10 Good

"Travelled to St Louis for a quick trip. Had an early flight and went straight to hotel to request an early check in. Upon arrival I requested a 2 hour early check in. The lady at the check in desk was rude and immediately shut me down. So, we gambled, ate lunch and waited. 2 hours before check-in, I noticed plotters were checking in and getting keys, so I approached a gentleman and asked him if I could also check in, which he did accommodate. Was grateful for him. So, my first impression was not the best."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"We have stayed at this Drury several times. Never disappointed. The staff is very helpful and friendly, the food is good, and the location is easy for lots to do and see. This is great for families wanting to save some money on meals and have a location that is safe and easy to get to local sights. Highly recommend."

Ameristar Casino Resort and Spa

10/10 Excellent

"I'll tell you what. I visited the Ameristar for a fun weekend reunion with a long time college friend I hadn't seen in 30 years. We had plans to see the city, eat Italian on the Hill, go see the arch, see the city museum. But no...we left one time to go to a diner around the corner for breakfast and realized we had no desire to leave the hotel again. The food was amazing, the people (most likely regulars) were hilarious and fun. The pool was to die for. The bartenders at the pool were amazing and fun. We went to see the cover band at one of the bars on Saturday night and the place was PACKED. I think people were there just to go see them. Costumes, mullet wigs, 90's hair band...it was so fun. Will most DEFINITELY be back. Can't say enough good things. The rooms were HUGE and lovely. There were 17 pillows to choose from for your firmness desire (okay, maybe just 4 but still...). We had a blast."

Frequently asked questions

What's it like in Penrose?

Travellers are sure to enjoy a stay in St. Louis's Penrose neighbourhood. Consider a visit to Julia Davis Branch Library as part of your Penrose travel plans.

If I need to cancel my hotel reservation in Penrose, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to get top deals in Penrose.

What is there to do around this St. Louis neighbourhood?

Julia Davis Branch Library is an attraction you might want to check out while you're in Penrose. Shelley House and Bellefontaine Cemetery are also worth a visit when you're out sightseeing in St. Louis.

Hotels in Penrose, St. Louis

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Our top choices for Penrose hotels

1. Hampton Inn & Suites St. Louis at Forest Park

2. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

3. Drury Plaza Hotel St. Louis Union Station

4. Home2 Suites by Hilton St. Louis/Forest Park

5. Fairfield Inn & Suites by Marriott St. Louis Downtown

6. Drury Plaza Hotel St. Louis at the Arch

7. Aloft by Marriott St Louis Central West End

8. The Royal Sonesta Chase Park Plaza St. Louis

9. Pear Tree Inn St. Louis Near Union Station

10. Embassy Suites by Hilton St. Louis Downtown

11. Moonrise Hotel

12. Hotel Indigo St Louis - Central West End by IHG

13. Drury Inn & Suites St. Louis Forest Park

14. DoubleTree by Hilton St. Louis Forest Park

15. AC Hotel St. Louis Central West End

16. Home2 Suites by Hilton St. Louis Downtown

17. Hyatt Select St. Louis Airport

18. Courtyard by Marriott St. Louis Downtown/Convention Center

19. Hyatt Regency St. Louis at The Arch

20. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Where to stay in Penrose

Downtown St. Louis

Clayton

Central West End

Creve Coeur

St. Charles Historic District

Top Penrose Hotel Reviews

Hollywood Casino & Hotel St. Louis

Frequently asked questions