Hotels near Penn Presbyterian Medical Center

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Our top choices for Penn Presbyterian Medical Center hotels

Property entrance
The Study at University City

The Study at University City

The Study at University City
4.0 star property
University City, 1 km from Penn Presbyterian Medical Center
9.4 out of 10, Exceptional, (1000)
"The staff were friendly and helpful. The room was spotless. We had dinner in the onsite restaurant and it was delicious."
United States
Kathryn
The price is RM806
RM937 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Study at University City
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
The Inn at Penn, A Hilton Hotel

The Inn at Penn, A Hilton Hotel

The Inn at Penn, A Hilton Hotel
4.0 star property
University City, 0.6 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1001)
"The room was indeed spotless. The valet were excellent and we enjoyed our stay."
United States
Larry
The price is RM644
RM749 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Inn at Penn, A Hilton Hotel
Lobby
The Gables B&B Philadelphia

The Gables B&B Philadelphia

The Gables B&B Philadelphia
4.0 star property
1.7 km from Penn Presbyterian Medical Center
9.8 out of 10, Exceptional, (453)
"I really loved the historical feeling of this beautiful property, and even though I was staying for work, it was a great place to spend a few evenings! Loved it!"
United States
Cailyn
The price is RM891
RM1,029 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Gables B&B Philadelphia
Living area
4211 Suites

4211 Suites

4211 Suites
4.5 star property
0.7 km from Penn Presbyterian Medical Center
9.0 out of 10, Wonderful, (517)
"Room was clean and roomy, staff was excellent! "
United States
Joseph
The price is RM539
RM628 total
includes taxes & fees
1 Jan - 2 Jan 2026
4211 Suites
2 restaurants, breakfast, lunch, dinner served; seafood
Four Seasons Hotel Philadelphia at Comcast Center

Four Seasons Hotel Philadelphia at Comcast Center

Four Seasons Hotel Philadelphia at Comcast Center
5.0 star property
Center City West, 2.5 km from Penn Presbyterian Medical Center
9.8 out of 10, Exceptional, (281)
"View was amazing "
United States
Adam
The price is RM4,291
RM4,994 total
includes taxes & fees
6 Jan - 7 Jan 2026
Four Seasons Hotel Philadelphia at Comcast Center
Full breakfast for a fee on weekdays
Fitler Club

Fitler Club

Fitler Club
4.0 star property
Center City West, 1.8 km from Penn Presbyterian Medical Center
9.4 out of 10, Exceptional, (280)
"Great overall experience; everything was great!"
United States
Juan
Fitler Club
Exterior
AKA University City

AKA University City

AKA University City
4.0 star property
University City, 1.6 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (712)
"great views of Philly!"
United States
Sara
The price is RM1,035
RM1,322 total
includes taxes & fees
7 Jan - 8 Jan 2026
AKA University City
Restaurant
The Maj Hotel

The Maj Hotel

The Maj Hotel
3.0 star property
2.1 km from Penn Presbyterian Medical Center
9.4 out of 10, Exceptional, (423)
"Very clean rooms and attentive staff. The location , close to Barnes foundation and the Art Museum was very important for me."
United States
Eugeni
The Maj Hotel
Food and drink
The Rittenhouse Philadelphia

The Rittenhouse Philadelphia

The Rittenhouse Philadelphia
5.0 star property
Rittenhouse Square, 2.4 km from Penn Presbyterian Medical Center
9.6 out of 10, Exceptional, (942)
"Very clean and great amenities!"
United States
Brendan
The price is RM1,597
RM2,023 total
includes taxes & fees
6 Jan - 7 Jan 2026
The Rittenhouse Philadelphia
Premium bedding, down duvets, individually decorated
The DWIGHT D Hotel

The DWIGHT D Hotel

The DWIGHT D Hotel
5.0 star property
Rittenhouse Square, 2.9 km from Penn Presbyterian Medical Center
9.8 out of 10, Exceptional, (385)
"Friendly and helpfull owners."
United States
Frank
The price is RM1,113
RM1,286 total
includes taxes & fees
28 Jan - 29 Jan 2026
The DWIGHT D Hotel
Private kitchen
La Reserve Bed & Breakfast

La Reserve Bed & Breakfast

La Reserve Bed & Breakfast
3.5 star property
Rittenhouse Square, 2.7 km from Penn Presbyterian Medical Center
9.4 out of 10, Exceptional, (447)
"One of the loveliest places I have stayed -- it was as if i was living in a Victorian home on Pine Street in Philadelphia."
United States
Anne-Marie
La Reserve Bed & Breakfast
Exterior
ROOST Midtown

ROOST Midtown

ROOST Midtown
4.0 star property
Center City West, 3 km from Penn Presbyterian Medical Center
9.6 out of 10, Exceptional, (387)
"Super convenient to office at Liberty place. Very spacious apartment that was nearly brand new. "
United States
Jessica
The price is RM616
RM711 total
includes taxes & fees
5 Jan - 6 Jan 2026
ROOST Midtown
Lobby
Sheraton Philadelphia University City Hotel

Sheraton Philadelphia University City Hotel

Sheraton Philadelphia University City Hotel
3.5 star property
University City, 0.6 km from Penn Presbyterian Medical Center
8.4 out of 10, Very good, (1001)
"Good breakfast, great view, friend,y stay, epic location "
United States
Adrienne
The price is RM582
RM677 total
includes taxes & fees
25 Jan - 26 Jan 2026
Sheraton Philadelphia University City Hotel
3 restaurants, breakfast, lunch, dinner served; Mexican cuisine
Motto by Hilton Philadelphia Rittenhouse Square

Motto by Hilton Philadelphia Rittenhouse Square

Motto by Hilton Philadelphia Rittenhouse Square
3.5 star property
Center City West, 2.5 km from Penn Presbyterian Medical Center
9.0 out of 10, Wonderful, (1921)
"Super friendly staff and the Mexican restaurant is delicious. "
United States
Christina
The price is RM362
RM421 total
includes taxes & fees
25 Jan - 26 Jan 2026
Motto by Hilton Philadelphia Rittenhouse Square
Exterior
Hyatt Centric Center City Philadelphia

Hyatt Centric Center City Philadelphia

Hyatt Centric Center City Philadelphia
4.0 star property
Rittenhouse Square, 2.9 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1554)
"Great location, friendly staff, nice rooms"
United States
Eric
The price is RM644
RM749 total
includes taxes & fees
19 Jan - 20 Jan 2026
Hyatt Centric Center City Philadelphia
Meeting facility
Element Philadelphia Downtown

Element Philadelphia Downtown

Element Philadelphia Downtown
4.0 star property
Center City West, 3 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1346)
"Clean room, smiley staff and cozy lovely lobby 💜"
United States
Hilal
The price is RM547
RM636 total
includes taxes & fees
19 Jan - 20 Jan 2026
Element Philadelphia Downtown
Exterior
AKA Rittenhouse Square

AKA Rittenhouse Square

AKA Rittenhouse Square
4.0 star property
Center City West, 2.6 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (509)
"Staff, amenities, room was beautiful!"
United States
Maria
AKA Rittenhouse Square
Premium bedding, in-room safe, individually decorated
The Franklin on Rittenhouse, A Boutique Hotel

The Franklin on Rittenhouse, A Boutique Hotel

The Franklin on Rittenhouse, A Boutique Hotel
4.0 star property
Rittenhouse Square, 2.7 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1001)
"Staff, amenities, great room"
United States
Phyllis
The price is RM1,031
RM1,327 total
includes taxes & fees
14 Jan - 15 Jan 2026
The Franklin on Rittenhouse, A Boutique Hotel
Interior
Club Quarters Hotel Rittenhouse Square, Philadelphia

Club Quarters Hotel Rittenhouse Square, Philadelphia

Club Quarters Hotel Rittenhouse Square, Philadelphia
4.0 star property
Center City West, 2.8 km from Penn Presbyterian Medical Center
9.0 out of 10, Wonderful, (4272)
"Perfect stay! "
United States
Phuong
The price is RM471
RM548 total
includes taxes & fees
6 Jan - 7 Jan 2026
Club Quarters Hotel Rittenhouse Square, Philadelphia
Exterior
Sofitel Philadelphia at Rittenhouse Square

Sofitel Philadelphia at Rittenhouse Square

Sofitel Philadelphia at Rittenhouse Square
4.5 star property
Center City West, 2.7 km from Penn Presbyterian Medical Center
9.0 out of 10, Wonderful, (2238)
"Comfy beds great location "
United States
Shannon
The price is RM650
RM889 total
includes taxes & fees
5 Jan - 6 Jan 2026
Sofitel Philadelphia at Rittenhouse Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Penn Presbyterian Medical Center Hotel Reviews

Sheraton Philadelphia University City Hotel

Sheraton Philadelphia University City Hotel

10/10 Excellent
"We stayed for about 2 hours Enroute to NYC and the staff was great."
Forrest 1-night trip
Posted 2 days ago
Sheraton Philadelphia University City Hotel

Hotels near other Penn Presbyterian Medical Center attractions

uCity Square

You can find out about the history of Philadelphia when you stop by uCity Square. While you're here, you can savour the top-notch restaurants.
See properties

Philadanco

You can enjoy some culture when you stop by Philadanco in Philadelphia. While you're here, you can savour the top-notch restaurants.
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Frequently asked questions

What's the area like around Penn Presbyterian Medical Center?
Penn Presbyterian Medical Center is located in Philadelphia. This welcoming area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 146 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Penn Presbyterian Medical Center?
Adjacent to Penn Presbyterian Medical Center, Kasa The Niche University City Philadelphia is one of the top choices for your stay based on our traveller data, and this guest house offers free WiFi and LCD TVs. Other good options close by include 4211 Suites and The Inn at Penn, A Hilton Hotel.
How many hotels will I be able to find near Penn Presbyterian Medical Center?
Expedia has 146 hotels and other accommodation options within a mile from Penn Presbyterian Medical Center.
If I need to cancel the hotel reservation for my stay near Penn Presbyterian Medical Center, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to get the best options available near Penn Presbyterian Medical Center.
What can I see and do near Penn Presbyterian Medical Center?
Penn Museum, Philadelphia Museum of Art and The Mütter Museum feature captivating exhibits. Sights like Franklin Field, Rocky Steps and Eastern State Penitentiary are must-sees while exploring the area. You can catch a show at Academy of Music, Kimmel Center for the Performing Arts and Miller Theater.
How can I get to Penn Presbyterian Medical Center?
With so many choices for transport, exploring the area around Penn Presbyterian Medical Center is a breeze. You can walk to nearby metro stations including Penn Medicine Station, 33rd St Station and 37th St Station. If you want to journey outside of the area, hop aboard a train from Philadelphia University City Station, 30th St Station or Philadelphia, PA (ZFV-30th Street Rail Station).