Top 10 Main Street Hotels of 2026

Ann Arbor, Michigan, USA Downtown Panorama

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Where to stay in Main Street

Find the best Main Street areas for the activities you enjoy most.

South Central

If you're spending some time in South Central, Yost Ice Arena and Michigan Stadium are top sights worth seeing.

See properties

Downtown

If you're spending some time in Downtown, Ann Arbor Hands On Museum and Kempf House Museum are top sights worth seeing.

See properties

Aerial View of Burton Memorial Tower in Ann Arbor Campus

Old West Side

If you're looking for some top things to see and do in Old West Side and surrounding area, you can visit Ann Arbor Hands On Museum and University of Michigan Museum of Art.

See properties

Aerial View of Railway Bridge and Dam on Huron River in Autumn

Bryant Pattengill East

If you're spending some time in Bryant Pattengill East, Cobblestone Farm and Buhr Park are top sights worth seeing.

See properties

Central Campus Medical

While visiting Central Campus Medical, you might make a stop by sights like Exhibit Museum of Natural History at the University Of Michigan and Hill Auditorium.

See properties

Top Main Street Hotel Reviews

The Kensington Hotel

8/10 Good

"No bathroom amenities and the bathrooms need updating."

Weber's Hotel & Restaurant

10/10 Excellent

"I wish I stayed another day if I had the time I would have. I had a small corner room. It’s kind of tiny, but it was fine. The shower was probably the best part and the bed was very comfortable. No complaints. everything was great. I wasn’t unable to use the amenities because of my schedule and I was there for a business trip but dinner was superb. The cocktails were perfect. My meal was perfect. honestly I would definitely fly back there just to eat at the restaurant."

Saint John's Resort

8/10 Good

"My room was gorgeous and perfect for the work day I had planned. The service was not what you would expect at a 4 diamond/4 star hotel. I was given the Hotels $20 meal credit and told I could use it on room service. Called room service multiple times and just kept getting busy signals. Called the Front Desk and also just kept getting busy signals. Finally called the resort from my cell phone and someone picked up. I was told that the only restaurant serving room service closed early that evening. No guidance or help, just that information. After inquiring I learned that the only food available was at a restaurant at the other end of the resort. I could not find the phone number for this restaurant anywhere; needed to call back and have the front desk person connect me. Ordered, made the long walk there and back, and discovered in my room that they had not given me what I had ordered. There was no way I was going to walk all the way back to fix it. The next day morning just before 9am there was a fire drill for the hotel staff - was thankful that I had not planned to sleep in. I was able to use the meal credit for breakfast, though they had run out of the item I wanted. Anyway, the room was gorgeous and perfect, which was what mattered most to me."

Days Inn by Wyndham Ann Arbor

2/10 Terrible

"The hotel looks nothing like the pictures. I felt so unsafe here I got there and immediately left, was told they would approve a refund because I was led astray, and just got denied the refund because Expedia couldn’t get ahold of anyone to approve it for days. I’m out of 150 bucks for this disgusting place."

Stadium Suites

6/10 Okay

"We booked two rooms for our trip. Our rooms were booked by the host in separate buildings...far from each other. Both of the rooms we were given were not cleaned upon our arrival, which was well after the check in time. It took a while to get new rooms. I had to go out of my way to suggest that our rooms, which were booked together, were in the same building. The rooms were nice. I will say that I didn't feel very safe as a women staying on this property. There isn't much protecting you from strangers. The room doors have deadbolts but with no employees onsite I didn't feel as safe. The rooms were very clean and as expected. You can hear everything going on in the rooms above you. So, if you are a light sleeper this may not be your best option. It was nice having onsite parking in a secure garage. It would have been nicer if we were able to access the garage by one of the other doors closer to our assigned building, rather than having to navigate all the way back to the garage door itself. The garage door is closest to building 1-5...if you are staying the the other higher number buildings you will need to lug your luggage a long way. I'd stay here with a group. I would not stay here alone as a woman for safety reasons. You are better off at a hotel."

Frequently asked questions

What is Main Street like?

Main Street is a neighbourhood that travellers like for its art, university setting and entertainment choices.

If I need to cancel my hotel reservation in Main Street, will I receive a refund?

Yes, most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to view top deals in Main Street.

What is there to do around this Ann Arbor neighbourhood?

Ann Arbor Hands On Museum, Ann Arbor Art Center and Kempf House Museum are just a few of the places to visit in and around Main Street. When you're sightseeing in Ann Arbor, Kelsey Museum of Archaeology at the University of Michigan and Hill Auditorium are also worth a stop.

Hotels in Main Street, Ann Arbor

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Main Street hotels

Baymont by Wyndham Milan

Your Motel

Spark by Hilton Plymouth

Wyndham Garden Ann Arbor

Red Roof Inn Ann Arbor - U of Michigan South

Wingate by Wyndham Brighton

Country Meadow inn

La Quinta Inn by Wyndham Detroit Canton

Hampton Inn Saline

Hilton Garden Inn Plymouth

Hampton Inn & Suites Detroit-Canton

Holiday Inn Express & Suites Plymouth - Ann Arbor Area by IHG

Spark by Hilton Ann Arbor South

Red Roof Inn PLUS+ Ann Arbor - U of Michigan North

Baymont by Wyndham Chelsea

Candlewood Suites Brighton by IHG

Stadium Suites

Hampton Inn & Suites Ypsilanti

Home2 Suites By Hilton Ann Arbor South

Homewood Suites by Hilton Ann Arbor

Where to stay in Main Street

South Central

Downtown

Old West Side

Bryant Pattengill East

Central Campus Medical

Top Main Street Hotel Reviews

The Kensington Hotel

Frequently asked questions

Explore a world of travel with Expedia