Isle of Palms

Jacksonville

Popular places to visit

Mayo Clinic Florida

Mayo Clinic Florida

If Mayo Clinic Florida is what brings you to town, hopefully you'll have a chance to explore more of Jacksonville.

Mayo Clinic Florida
Jacksonville Naval Air Station

Jacksonville Naval Air Station

After visiting Jacksonville Naval Air Station, make a plan to see the other sights and activities in Jacksonville. Experience the lively festivals or attend a sporting event in this family-friendly area.

Jacksonville Naval Air Station
EverBank Field featuring a lake or waterhole

EverBank Stadium

5/5(1 review)

Capable of seating over 80,000 fans, this modern football stadium is the exciting home of the Jacksonville Jaguars, international soccer games and music events.

EverBank Stadium
Jacksonville Zoo and Gardens

Jacksonville Zoo and Gardens

5/5(1 review)

Admire thousands of animals and plants across entertaining exhibits in this family-friendly zoo that also has a children’s play area and a 4-D experience.

Jacksonville Zoo and Gardens
TPC Sawgrass

TPC Sawgrass

4.5/5(5 reviews)

Enjoy a round of golf in Ponte Vedra Beach at TPC Sawgrass. Stroll along the area's seaside or experience its acclaimed theatre scene.

TPC Sawgrass
Jacksonville Beach Pier

Jacksonville Beach Pier

5/5(1 review)

Stroll along this charming fishing pier that extends into the Atlantic Ocean. Enjoy the tranquil surroundings in your pursuit of a big catch.

Jacksonville Beach Pier

Things to do

Sea Dragon Airboat Safari

Airboat Adventure in Saint Augustine with a Guide

RM336
per adult
100% of travellers recommend
Airboat Adventure in Saint Augustine with a Guide
Chocolate Bar Class

Chocolate Bar Class - Hands on class

RM71
per adult
Chocolate Bar Class - Hands on class
Hand Pulled Lollipop Class

Hand Pulled Lollipop - Hard Candy Class

RM57
per traveller
88% of travellers recommend
Hand Pulled Lollipop - Hard Candy Class
Architecture and History Tour in San Marco

Architecture and History Tour in San Marco

RM405
per adult
Architecture and History Tour in San Marco
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

RM588
per traveller
90% of travellers recommend
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports
St. Augustine: St. Johns River Airboat Safari with a Guide

St. Augustine: St. Johns River Airboat Safari with a Guide

RM336
per adult
100% of travellers recommend
St. Augustine: St. Johns River Airboat Safari with a Guide
See all activities in Jacksonville

Top hotels in Isle of Palms

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
The price is RM668 per night from 25 Oct to 26 Oct
RM668
RM758 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (429 reviews)
"The lights seem to be out in the parking lot. It was extremely dark in the morning and hard to see to get to car. Seems unsafe. Lights need to be turned on. Otherwise, excellent stay"

Reviewed on 13 Oct 2025

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr, Jacksonville, FL
The price is RM685 per night from 6 Nov to 7 Nov
RM685
RM785 total
6 Nov - 7 Nov
includes taxes & fees
Stay at this 4-star eco-certified hotel in Jacksonville. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,326 reviews)
"The breakfast was amazing. the bathroom floors need to be clean. everything else was excellent. you can see the dirt within the grout"

Reviewed on 17 Oct 2025

Hyatt Regency Jacksonville
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N, Jacksonville Beach, FL
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the bar in ...
8.8/10 Excellent! (3,290 reviews)
"Was a nice place to stay. Wasn’t our brand of motel but we made out and had a good trip."

Reviewed on 17 Oct 2025

Get rates
Margaritaville Jacksonville Beach
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

3 out of 5
14565 Duval Rd, Jacksonville, FL
The price is RM393 per night from 2 Nov to 3 Nov
RM393
RM446 total
2 Nov - 3 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,137 reviews)
"Very helpful staff."

Reviewed on 17 Oct 2025

Hyatt Place Jacksonville Airport
Omni Amelia Island Resort & Spa

Omni Amelia Island Resort & Spa

4 out of 5
39 Beach Lagoon Road, Fernandina Beach, FL
The price is RM1,078 per night from 22 Oct to 23 Oct
RM1,078
RM1,397 total
22 Oct - 23 Oct
includes taxes & fees
Stay at this 4-star beach resort in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (1,014 reviews)
"Beautiful property with exceptional staff. Deidra at the front desk was very friendly and professional. Made us feel at home."

Reviewed on 18 Oct 2025

Omni Amelia Island Resort & Spa
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road, I-95 Exit 344 (Butler Boulevard), Jacksonville, FL
The price is RM295 per night from 9 Nov to 10 Nov
RM295
RM334 total
9 Nov - 10 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,766 reviews)
"Greatest service"

Reviewed on 18 Oct 2025

Wyndham Garden Jacksonville
See all 3,149 properties in Isle of Palms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Isle of Palms

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Atlantic Shores

If you're looking for some top things to see and do in Atlantic Shores and surrounding area, you can visit Pablo Plaza Shopping Center and Oceanfront Park.

Atlantic Shores
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Old Ponte Vedra Beach

While visiting Old Ponte Vedra Beach, you might make a stop by sights like Ponte Vedra Beach and Mickler Beach.

Old Ponte Vedra Beach
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Deerwood

While Deerwood isn't home to many top sights, St. Johns Town Center and UNF Arena are some notable places to visit nearby.

Deerwood
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Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Sawgrass
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Palm Valley

If you're spending some time in Palm Valley, TPC Sawgrass and Cornerstone Park are top sights worth seeing.

Palm Valley
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Arlington

If you're spending some time in Arlington, Regency Square Mall and Jacksonville Arboretum and Gardens are top sights worth seeing.

Arlington

Isle of Palms