10 Best Business Hotels in Florida Keys for 2026

A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Our top choices for Florida Keys business-friendly hotels

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a view of the ocean.

A hotel room with a large bed, a TV mounted on a wooden cabinet, and a balcony with a view of palm trees.

A modern kitchen with a marble island, wooden cabinets, and pendant lighting.

A hotel room with a balcony, a bed, a desk, and two chairs.

1. Hampton Inn Key West FL

Key West

Heylin

RM568

RM639 total

includes taxes & fees

27 Oct - 28 Oct

A pool area with lounge chairs and umbrellas, surrounded by palm trees.

An outdoor patio area with tables and chairs, a bar area with a counter and bar stools, and a TV mounted on the wall.

A hotel room with a large bed, a wooden nightstand, a desk, a chair, and a window with curtains.

A wooden outdoor dining table set with glassware, candles, and lanterns, surrounded by lush greenery.

2. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

New Town

Jacob

RM448

RM619 total

includes taxes & fees

1 Nov - 2 Nov

A wooden boardwalk with a palm tree and lamp post, leading to a waterfront.

A modern restaurant with a wooden counter, seating area, and large windows.

A hotel room with a desk, two beds, a TV, a ceiling fan, and a balcony with curtains.

A covered outdoor area with wooden tables and chairs, a view of the water, and a wooden deck with railings.

3. Courtyard by Marriott Key West Waterfront

Northside Resort

Patrick

RM650

RM731 total

includes taxes & fees

27 Oct - 28 Oct

A hotel room with a bed, a view of the beach, a hammock, and beach chairs.

A beachfront restaurant with outdoor seating, a seafood sign, and a market sign.

A beachfront hotel with multiple colorful buildings, a pool area, and a boat dock.

A pool area with blue lounge chairs, a hot tub, and a covered seating area.

4. Ibis Bay Beach Resort

Northside Resort

Sebastian

RM438

RM625 total

includes taxes & fees

27 Oct - 28 Oct

A beachside resort with palm trees, outdoor seating, and a food truck.

A hotel room with a bed, a sofa, a round table with a book, a window with a view, and a radiator.

A modern cafe with a wooden counter, seating area, and shelves stocked with beverages.

5. Blue Flamingo Resort Key West

New Town

Gabriel

RM474

RM763 total

includes taxes & fees

27 Oct - 28 Oct

A pool area with lounge chairs and gazebos, surrounded by palm trees.

A modern dining area with multiple tables and chairs, large windows, and ceiling fans.

An outdoor patio area with tables and chairs, umbrellas, and palm trees.

A spacious room with a high ceiling, large windows, and a view of palm trees.

6. DoubleTree Resort by Hilton Grand Key - Key West

Key West

Danee

RM485

RM683 total

includes taxes & fees

29 Oct - 30 Oct

A swimming pool with lounge chairs and palm trees.

A bar area with a wooden counter, bar stools, and a sign that reads 'So we BEATON.'

A covered outdoor seating area with a central bar, patterned chairs, and a decorative sign.

7. Hilton Garden Inn Key West / The Keys Collection

New Town

Darlene

RM449

RM620 total

includes taxes & fees

29 Oct - 30 Oct

A resort pool with clear blue water, surrounded by palm trees and lounge chairs.

A cozy room with wicker furniture, a glass coffee table, and a view of lush greenery outside.

A bar setting with a bartender preparing a drink, a counter with various bottles, and a TV screen in the background.

A spacious lobby with a central seating area, two staircases, and multiple potted plants.

8. Havana Cabana at Key West

New Town

Stephanie

RM662

RM1,005 total

includes taxes & fees

15 Nov - 16 Nov

View all properties

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent

"Amazing hotel with lots of on-site amenities and options for dinner. Loved the fishing in the morning."

Fairfield Inn & Suites by Marriott Marathon Florida Keys

10/10 Excellent

"I cannot say enough good things about this location. What an amazing experience. I’m so grateful for everything! Room was spacious, comfortable, and the property is spectacular. Can’t wait to visit again."

Amara Cay Resort

10/10 Excellent

"Great property however the rooms could use an update."

Islander Resort

10/10 Excellent

"💜"

The Pelican Key Largo Cottages

10/10 Excellent

"Absolutely loved our trip. The pelican reef was wonderful. The staff was excellent. It was clean comfortable and we really enjoyed the time we spent there."

Hampton Inn Key Largo Manatee Bay

10/10 Excellent

"I had a wonderful 7 day stay. The staff was outstanding. The breakfast buffet was good. The workers were prompt in maintaining the breakfast bar and quick to clean off a table. My room was clean and comfortable. The beach area could have used more sand because it had ruts in it from water flow, but there was ample seating. The pool area was nice. Lounge chairs, tables and chairs in good condition. Very nice outside tiki bar with plenty of seating as well. The sunsets from the beach area were amazing! If I ever travel back to Key Largo, I will stay here again."

Sunset Cove Beach Resort

10/10 Excellent

"Unique location and pet friendly"

Bayside Inn Key Largo

10/10 Excellent

"Great location. Pool was extremely warm and a bit cloudy due to suntan lotion. Floor in the suite was also dirty as in your feet will be covered in minutes"

Waterside Suites & Marina

10/10 Excellent

"😍"

Frequently asked questions

How much do business-friendly hotels in Florida Keys cost?

Prices for business hotels in Florida Keys range between RM351 and RM1,159 per night. No matter your budget, Expedia can help you locate the ideal space to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Florida Keys?

Florida Keys has multiple business-friendly hotels with a total average guest review rating of 9.1. Attending a work-related event in Key West? The Perry Hotel & Marina Key West is a 4-stars stay that comes highly recommended by corporate travellers and includes a nearby waterfront and a garden. Another excellent pick for an official business trip is Silver Palms Inn. Also in Key West, it has a 3.5-stars rating and conveniences such as an electric car charging station and a swimming pool.

How many business-friendly hotels are there in Florida Keys?

Florida Keys has 87 business-friendly hotels to pick from. Whether you're attending a conference or meeting or working remotely, these stays are equipped with the amenities you need to be productive.

What are the best cheap business-friendly hotels in Florida Keys?

That depends on which part of Florida Keys your working visit is taking you. If you're travelling to Key West, Best Western Hibiscus Motel meets the needs of business travellers at an affordable price. A spa tub and a restaurant are among its many conveniences. Meeting with clients in Key Largo? Check in to Coconut Palm Inn. Pool sun loungers and a garden help make this inexpensive property a favourite with corporate guests. Business-friendly hotels start from just RM351 a night, so your work trip doesn't have to be costly. Want to explore Florida Keys without blowing your budget? Take a break from your business events to visit cool free attractions like Smathers Beach in Key West. Key Largo also has plenty of things to do that won't cost a penny, including Baker's Cay Resort Beach. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in Florida Keys that are also business friendly?

If you're travelling for business in Florida Keys and bringing your family along with you, Expedia will help you find a suitable stay. Eden House in Key West is an ideal option for those juggling work and pleasure. This 3.5-stars property offers all the necessary amenities, like a sauna and a cafe. Hyatt Centric Key West Resort and Spa is another good choice in Key West. Combine corporate travel and quality time with your family at this 4-stars property. A nearby beach and WiFi are two of the many conveniences you'll find here. There are plenty of terrific things to do for the whole family in Key West. Smathers Beach and South Beach promise a great day out.

Are there any 5-star business-friendly hotels in Florida Keys?

While there aren't any 5-star business-friendly hotels in Florida Keys, there are still chic properties to choose from. Work taking you to Key West? The Perry Hotel & Marina Key West is a popular option that has everything you need while you're away from home on business. Amenities at this 4-star property include pillow top mattresses and designer toiletries. Ocean Key Resort - A Noble House Resort is another recommendation that caters to corporate travellers in Key West. Also rated 4 stars and featuring a swimming pool and a resort, you'll find plenty to love about this hotel.

Why book your business-friendly hotel in Florida Keys with Expedia?

Here at Expedia, our top task is to help you land a suitable stay at the right price. From deluxe, corporate-friendly getaways to affordable motels filled with all the amenities you need, you'll have your next work trip planned in a few quick clicks.

How can I find cheap business-friendly hotels in Florida Keys?

When work takes you on the road in Florida Keys, our "business friendly" filter will help you find the ideal hotel. From included breakfast and free WiFi to concierge services and conference spaces, they come with the amenities you need to be productive. You can also refine your search by your budget and preferred star rating to see the cheapest properties.

What is there to do in Florida Keys near my business-friendly hotel?

Whether you like shopping, dining, history or culture, Florida Keys is one place you'll never get bored! The well-known city of Key West has tons of attractions, including Smathers Beach, South Beach and Clarence S. Higgs Memorial Beach Park. If you're planning a work trip to Key Largo, Baker's Cay Resort Beach, Jimmy Johnson's Big Chill and Bluefin Rock Harbour Marina are worth putting on your itinerary.

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Florida Keys Business Hotels

Our top choices for Florida Keys business-friendly hotels

1. Hampton Inn Key West FL

2. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

3. Courtyard by Marriott Key West Waterfront

4. Ibis Bay Beach Resort

5. Blue Flamingo Resort Key West

6. DoubleTree Resort by Hilton Grand Key - Key West

7. Hilton Garden Inn Key West / The Keys Collection

8. Havana Cabana at Key West

9. Silver Palms Inn & Historic Homes

10. The Laureate Key West

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Fairfield Inn & Suites by Marriott Marathon Florida Keys

Amara Cay Resort

Islander Resort

The Pelican Key Largo Cottages

Hampton Inn Key Largo Manatee Bay

Sunset Cove Beach Resort

Bayside Inn Key Largo

Waterside Suites & Marina

Frequently asked questions

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