East Prairie hotels from RM243
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in East Prairie
Family friendly
Check prices for these dates
Our top choices for East Prairie hotels
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,005 reviews)
"Breakfast was good,pool hot tub excellent "
Janica
The price is RM440
RM506 total
includes taxes & fees
8 Jun - 9 Jun
Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (571 reviews)
"Very clean hotel with comfortable bedding. Front desk staff was very nice and accommodating as we were traveling with a small dog."
Connie
The price is RM471
RM533 total
includes taxes & fees
7 Jun - 8 Jun
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.6 out of 10, (637 reviews)
"Clean rooms,"
Karl
The price is RM236
RM262 total
includes taxes & fees
7 Jun - 8 Jun
The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (413 reviews)
"All very just okay "
Sherry
The price is RM297
RM330 total
includes taxes & fees
28 Jun - 29 Jun
Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,002 reviews)
"Breakfast was fresh and the room was clean. It's a good place to stay. Friendly staff. "
Tabitha
The price is RM400
RM456 total
includes taxes & fees
16 Jun - 17 Jun
New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very good, (767 reviews)
"Great stay with Great people, very clean and welcoming"
Mircea
The price is RM225
RM243 total
includes taxes & fees
7 Jun - 8 Jun
Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very good, (64 reviews)
"Great hotel for the price!!! Remodel very nice and modern. "
Amy
The price is RM365
RM417 total
includes taxes & fees
8 Jun - 9 Jun
Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union CityUnion City
8.6 out of 10, Excellent, (571 reviews)
"Very clean nice staff and well run "
zach
The price is RM237
RM282 total
includes taxes & fees
17 Jun - 18 Jun
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,001 reviews)
"When I stay at hotels I like to find hotels like this one for the $$$ value . This hotel was clean and the bed was very comfortable. Room 237 . I didn’t hear any interstate noise . I didn’t eat the breakfast but the coffee was very good . I would stay here again ."
Kurt
The price is RM285
RM325 total
includes taxes & fees
7 Jun - 8 Jun
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (84 reviews)
"Great stay, kind staff, very clean property."
Joni
The price is RM436
RM494 total
includes taxes & fees
21 Jun - 22 Jun
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (784 reviews)
"We were very satisfied with our stay. We will make this a regular stay when traveling to or from Iowa."
Carolyn
The price is RM268
RM305 total
includes taxes & fees
3 Jun - 4 Jun
Reelfoot Lake Inn
Reelfoot Lake InnTiptonville
7.2 out of 10, Good, (494 reviews)
"The lake view was beautiful and staff was amazing"
Richard
The price is RM276
RM317 total
includes taxes & fees
18 Jun - 19 Jun
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
6.8 out of 10, (634 reviews)
"Staff, A/C, adequate breakfast"
David
The price is RM250
RM285 total
includes taxes & fees
7 Jun - 8 Jun
Hospitality House Union City I 69 / US 51
Hospitality House Union City I 69 / US 51Union City
6.8 out of 10, (393 reviews)
"Yes"
Lashae
The price is RM226
RM268 total
includes taxes & fees
6 Jun - 7 Jun
Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of AmericaUnion City
9.2 out of 10, Wonderful, (395 reviews)
"Great stay. "
Paul
The price is RM346
RM411 total
includes taxes & fees
24 Jun - 25 Jun
Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (286 reviews)
"the hotel needs updateing poor brekfesr"
DANIEL
The price is RM288
RM319 total
includes taxes & fees
20 Jun - 21 Jun
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (466 reviews)
"Only stayed one night, no complaints"
Zachary
The price is RM416
RM471 total
includes taxes & fees
21 Jun - 22 Jun
Quality Inn Union City US 51
Quality Inn Union City US 51Union City
8.4 out of 10, Very good, (517 reviews)
"Breakfast was filling and fresh.
Short overnight stay which completely met our needs
First level room with convenient vehicle parking right outside the door which made moving luggage painless. "
Lisa
The price is RM246
RM292 total
includes taxes & fees
23 Jun - 24 Jun
Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
6.8 out of 10, (139 reviews)
"Enjoyed our stay. All the appliances worked and our air conditioner kept us cool! Will definitely stay here again!"
Sheryl
The price is RM223
RM266 total
includes taxes & fees
4 Jun - 5 Jun
Hampton Inn Union City
Hampton Inn Union CityUnion City
9.6 out of 10, Exceptional, (184 reviews)
"The room was clean and comfortable. The staff was courteous during my entire stay."
Alvin
The price is RM435
RM517 total
includes taxes & fees
14 Jun - 15 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular East Prairie attractions
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.
Top East Prairie Hotel Reviews
Hospitality House Union City I 69 / US 51
2/10 Terrible
More cheap stays in East Prairie
Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
The price is RM250 per night from 7 Jun to 8 Jun
RM250
RM285 total
7 Jun - 8 Jun
includes taxes & fees
6.8/10 (634 reviews)
