Photo by Jen - Nealys On Wheels

Search Alexander County Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
7 Aug - 8 Aug
Tomorrow
8 Aug - 9 Aug
This weekend
8 Aug - 10 Aug
Next weekend
15 Aug - 17 Aug

Filter by

Guest rating
Guest rating
Property class

Top Hotels in Alexander County

Quality Inn Cairo I-57
Relax in the stylish lobby, featuring a reception desk, comfortable seating areas, and beautiful artwork.

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (264)
"The hotel is in need of some serious upkeep and cleaning. It is in fairly poor condition, but it the only hotel in town."
The price is RM294
RM327 total
includes taxes & fees
7 Sept - 8 Sept
Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO
Welcome to Simmons Hotel, where guests can enjoy a convenient covered entrance and parking.

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (578)
"Located very close to the expanse of corn fields, quiet, clean rooms, everything is neat, the bathroom is also very clean. Friendly receptionist."
The price is RM252
RM279 total
includes taxes & fees
24 Aug - 25 Aug
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
Two single beds with matching headboards, a wooden dresser, and a desk with a chair.

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (397)
"I consistently choose to stay there due to positive past encounters."
The price is RM287
RM319 total
includes taxes & fees
4 Sept - 5 Sept
Quality Inn Charleston - Sikeston
Eagle Inn Charleston
Two single beds with white linens and dark headboards, a green accent wall, and a window with a brown curtain.

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (100)
"Comfortable bed, easy access to room"
The price is RM270
RM299 total
includes taxes & fees
4 Sept - 5 Sept
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Alexander County Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"The facility is clean, the rooms are clean and big, the staff is friendly and helpful. The breakfast was wonderful with plenty of options. The evening drinks and food is a great addition to your amenities. Anything we needed was given to us with smiles. I would recommend this facility over and over. We also had a great time in the pool and hot tub!!"
Vivian 2-night trip
Posted 1 day ago
Drury Plaza Hotel Cape Girardeau Conference Center