Cairo hotels from RM242

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Apr - 28 Apr
Tomorrow
28 Apr - 29 Apr
This weekend
1 May - 3 May
Next weekend
8 May - 10 May

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Cairo hotels

Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (284 reviews)
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
United States
Maurice
The price is RM303
RM337 total
includes taxes & fees
3 May - 4 May
Quality Inn Cairo I-57
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (630 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is RM250
RM277 total
includes taxes & fees
3 May - 4 May
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby sitting area

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
"All very just okay "
United States
Sherry
The price is RM297
RM330 total
includes taxes & fees
28 Apr - 29 Apr
The Riverstone Hotel Charleston-Sikeston
Living area

La Center Motel

La Center Motel
2.0 star property
La Center
7.6 out of 10, Good, (19 reviews)
"Property is located just outside of town, so very convenient yet slightly off the beaten path."
United States
Carrie
The price is RM214
RM250 total
includes taxes & fees
28 Apr - 29 Apr
La Center Motel
View from room

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
The price is RM218
RM242 total
includes taxes & fees
2 May - 3 May
Eagle Inn Charleston
Interior

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Cairo attractions

Fort Defiance State Park

3.7/5 (15 reviews)
Where the mighty Mississippi and Ohio rivers converge, Fort Defiance Park offers a rare view of this natural phenomenon. Explore the historic grounds where Lewis and Clark once trained the Corps of Discovery in 1803.
See properties

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artefacts from this once-thriving river port town.

See all hotels in Cairo
Cairo Ohio River Bridge traversing over the Ohio River at sunset

Top Cairo Hotel Reviews

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

2/10 Terrible
"Coffee "
James 5-night trip
Posted 5 days ago
The Riverstone Hotel Charleston-Sikeston

More cheap stays in Cairo

Eagle Inn Charleston

Eagle Inn Charleston

2811 East Marshall Street Charleston MO
The price is RM218 per night from 2 May to 3 May
RM218
RM242 total
2 May - 3 May
includes taxes & fees
6.6/10 (106 reviews)

Frequently asked questions

Where is the best place for a stay in Cairo?
Based on our traveller data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Two other choices for your stay in the area are Super 8 by Wyndham Charleston/Sikeston East MO and The Riverstone Hotel Charleston-Sikeston. See all available top hotels, or vacation rentals in Cairo.
If I need to cancel my hotel reservation in Cairo, will I receive a refund?
Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.
What is staying in Cairo like?
Visitors can enjoy all that Cairo has to offer, including the restaurants, entertainment choices and riverfront. This city also attracts tourists with its small-town vibe. There are 28 hotels and other accommodation options in the surrounding area. Find out more about Cairo.
What should I do while I'm visiting Cairo?
The picturesque setting of Mississippi River and Ohio River Valley exemplify the area's natural beauty. Additionally, you might want to add Fort Defiance State Park to your itinerary. Take a look at what more there is to see and do in Expedia's Cairo guide.
What's the seasonal weather like in Cairo?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cairo is 1540 mm.

Explore a world of travel with Expedia