Defiance hotels from RM285

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Nov - 13 Nov
Tomorrow
13 Nov - 14 Nov
This weekend
14 Nov - 16 Nov
Next weekend
21 Nov - 23 Nov

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Defiance hotels

Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
Fenton
8.0 out of 10, Very good, (1013)
"Good hotel"
United States
Kelly
The price is RM352
RM406 total
includes taxes & fees
30 Nov - 1 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Ballroom
The Wildwood Hotel

The Wildwood Hotel

3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1597)
"Great hotel in a great neighborhood "
United States
Linda
The Wildwood Hotel
Front of property
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3.0 star property
Chesterfield
8.0 out of 10, Very good, (1019)
"This was a very nice place to stay. Centrally located, very clean and quiet with a great breakfast!"
United States
Kirsti
The price is RM384
RM446 total
includes taxes & fees
23 Nov - 24 Nov
Sonesta ES Suites St. Louis - Chesterfield
Property amenity
Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton

2.5 star property
Warrenton
7.4 out of 10, Good, (1001)
"The room was amazing the jacuzzi tub worked great we love our stay at Baymont "
United States
Christopher
The price is RM354
RM406 total
includes taxes & fees
19 Nov - 20 Nov
Baymont by Wyndham Warrenton
Front of property
Super 8 by Wyndham Eureka/Six Flags Nearby

Super 8 by Wyndham Eureka/Six Flags Nearby

2.0 star property
Eureka
7.0 out of 10, Good, (1002)
"A much needed comfortable bed and hot shower, staff was lovely. "
United States
Rachel
The price is RM248
RM289 total
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham Eureka/Six Flags Nearby
Lobby
Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport

2.5 star property
Maryland Heights
8.0 out of 10, Very good, (1014)
"Clean rooms, courteous staff, good breakfast. Great stay at a reasonable price. "
United States
Shanna
The price is RM410
RM475 total
includes taxes & fees
13 Nov - 14 Nov
Best Western Plus St. Louis West-Westport
Exterior
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG

2.5 star property
Wentzville
9.4 out of 10, Exceptional, (821)
"Comfortable beds good shower "
United States
Chad
The price is RM505
RM604 total
includes taxes & fees
12 Dec - 13 Dec
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

2.5 star property
O'Fallon
8.6 out of 10, Excellent, (816)
"Clean, well maintained hotel. Friendly staff, great breakfast. Close to shopping and restaurants."
United States
Theresa
The price is RM393
RM464 total
includes taxes & fees
16 Nov - 17 Nov
Holiday Inn Express St. Louis West - O'Fallon by IHG
Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
O'Fallon
8.8 out of 10, Excellent, (1000)
"Nice breakfast, friendly staff"
United States
Damon
The price is RM365
RM431 total
includes taxes & fees
2 Dec - 3 Dec
Sleep Inn & Suites O'Fallon MO - Technology Drive
Lobby
Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles

2.0 star property
St. Peters
6.4 out of 10, (1000)
"Decent for the price"
United States
Kathie
The price is RM281
RM324 total
includes taxes & fees
23 Nov - 24 Nov
Days Inn by Wyndham St Peters/St Charles
1 bedroom, Egyptian cotton sheets, premium bedding, pillow-top beds
Best Western Plus Washington Hotel

Best Western Plus Washington Hotel

2.5 star property
Washington
9.2 out of 10, Wonderful, (626)
"Great breakfast, comfortable room, and wonderful staff, all for a reasonable price. We stay here every time we are in Washington."
United States
Kimberly
The price is RM534
RM608 total
includes taxes & fees
16 Nov - 17 Nov
Best Western Plus Washington Hotel
Daily buffet breakfast (USD 12.95 per person)
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3.0 star property
Chesterfield
8.2 out of 10, Very good, (779)
"Staff was courteous. "
United States
John
The price is RM404
RM470 total
includes taxes & fees
7 Dec - 8 Dec
Hilton Garden Inn Chesterfield
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
Fenton
7.8 out of 10, Good, (1085)
"Nice clean rooms."
United States
Chrysta
The price is RM327
RM378 total
includes taxes & fees
18 Nov - 19 Nov
Wingate by Wyndham St. Louis/Fenton Route 66
Front of property – evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 star property
Maryland Heights
8.4 out of 10, Very good, (2193)
"We had a pleasant stay."
United States
Larry
The price is RM319
RM431 total
includes taxes & fees
23 Nov - 24 Nov
Hollywood Casino & Hotel St. Louis
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1000)
"Hotel was very clean."
United States
christine
The price is RM458
RM531 total
includes taxes & fees
16 Nov - 17 Nov
Drury Plaza Hotel St. Louis St. Charles
In-room safe, desk, laptop workspace, blackout curtains
Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton

2.0 star property
Warrenton
7.4 out of 10, Good, (609)
"Ample free parking for our large RV. Staff was indifferent and acted like they were doing us a favor by letting us stay. Had to wait quite a while to be greeted for check in. Very limited lodging choices in the area, so??"
United States
Gary
The price is RM253
RM291 total
includes taxes & fees
19 Nov - 20 Nov
Super 8 by Wyndham Warrenton
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 star property
St. Charles
8.0 out of 10, Very good, (1000)
"polite staff, great service, nice breakfast, clean room "
United States
John
The price is RM394
RM453 total
includes taxes & fees
1 Dec - 2 Dec
Hampton Inn St. Charles St. Peters
Lobby
AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield

3.5 star property
Chesterfield
9.2 out of 10, Wonderful, (222)
"Newer hotel, very clean, up to date and in nice area. "
United States
Johnny
The price is RM526
RM610 total
includes taxes & fees
21 Nov - 22 Nov
AC Hotel by Marriott St. Louis Chesterfield
Exterior
Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

3.0 star property
Fenton
8.8 out of 10, Excellent, (1004)
"Spotless room great mattress and pillows and super friendly staff"
United States
judith
The price is RM488
RM564 total
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
In-room safe, laptop workspace, blackout curtains, iron/ironing board
Super 8 by Wyndham St. Clair MO

Super 8 by Wyndham St. Clair MO

2.0 star property
St. Clair
7.2 out of 10, Good, (932)
"Was what I needed after a long drive."
United States
Michael
The price is RM276
RM302 total
includes taxes & fees
19 Nov - 20 Nov
Super 8 by Wyndham St. Clair MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Defiance attractions

Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
See properties
Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
See properties

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

Top Defiance Hotel Reviews

Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

10/10 Excellent
"Spacious clean room, great breakfast and dinner."
Vicky 2-night trip
Posted 1 day ago
Drury Plaza Hotel St. Louis Creve Coeur

More cheap stays in Defiance

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1310 Bass Pro Drive, St. Charles, MO
The price is RM246 per night from 13 Nov to 14 Nov
RM246
RM285 total
13 Nov - 14 Nov
includes taxes & fees
5.6/10 (1,008 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and Hilton St. Louis Frontenac. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Offers an indoor pool, an outdoor pool and buffet. Hilton St. Louis Frontenac and La Quinta Inn & Suites by Wyndham St. Louis Westport are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 20 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

Explore a world of travel with Expedia