A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Defiance hotels from RM307

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Our top choices for Defiance hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,401 reviews)
"Will definitely stay again!"
United States
Trevor
The price is RM385
RM445 total
includes taxes & fees
5 Jul - 6 Jul
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (1,000 reviews)
"Staff was helpful, area was easy tp navigate. Place was great for the price"
United States
Ryan
The price is RM342
RM386 total
includes taxes & fees
7 Jul - 8 Jul
Quality Inn Foristell

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.2 out of 10, Very good, (1,009 reviews)
"Great location, of staying away from busy intersections!!"
United States
David
The price is RM343
RM394 total
includes taxes & fees
12 Jul - 13 Jul
Super 8 by Wyndham St Charles

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,000 reviews)
"Excellent place to stay!"
United States
Steven
The price is RM334
RM381 total
includes taxes & fees
22 Jul - 23 Jul
Baymont by Wyndham Warrenton

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.4 out of 10, Exceptional, (419 reviews)
"Great stay. Easy and quick check in."
United States
John
The price is RM449
RM541 total
includes taxes & fees
19 Jul - 20 Jul
Holiday Inn Express & Suites St Peters by IHG

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,007 reviews)
"We had a great stay"
United States
Alexa
The price is RM417
RM480 total
includes taxes & fees
19 Jul - 20 Jul
Comfort Suites St Charles - St Louis

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,006 reviews)
"Place was clean, staff was very friendly loved the hot tub!"
United States
Sophia
The price is RM501
RM586 total
includes taxes & fees
5 Jul - 6 Jul
Drury Inn & Suites Southwest St. Louis

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,264 reviews)
"nice place"
United States
diana
The price is RM363
RM420 total
includes taxes & fees
26 Jul - 27 Jul
Wingate by Wyndham St. Louis/Fenton Route 66

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,002 reviews)
"Good staff "
United States
Solomon
The price is RM464
RM533 total
includes taxes & fees
20 Jul - 21 Jul
Hampton Inn St. Charles St. Peters

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,031 reviews)
"We enjoyed our stay. The staff was very nice and the hotel was well kept and clean."
United States
Patrice
The price is RM342
RM404 total
includes taxes & fees
5 Jul - 6 Jul
Sleep Inn & Suites O'Fallon MO - Technology Drive

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (355 reviews)
"Was a good place to stay"
Canada
Blake
The price is RM373
RM430 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Plus Fenton

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
Wentzville
6.4 out of 10, (548 reviews)
"Room was clean but basic"
United States
James
The price is RM285
RM323 total
includes taxes & fees
14 Jul - 15 Jul
Economy Inn Wentzville

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (662 reviews)
"Terrific staff very helpful manager"
United States
Dale
The price is RM261
RM298 total
includes taxes & fees
5 Jul - 6 Jul
Super 8 by Wyndham Warrenton

Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,006 reviews)
"Nice place to stay. "
United States
David
The price is RM331
RM381 total
includes taxes & fees
5 Jul - 6 Jul
Country Inn & Suites by Radisson, St. Peters, MO

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (931 reviews)
"We have stay here before and requested to stay again. Great hotel."
United States
Steve
The price is RM568
RM676 total
includes taxes & fees
26 Jul - 27 Jul
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (701 reviews)
"Very clean and staff were friendly. Breakfast was good and will definitely stay here again. "
United States
Rod
The price is RM525
RM598 total
includes taxes & fees
13 Jul - 14 Jul
Best Western Plus Washington Hotel

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,008 reviews)
"Great location and clean hotel!"
United States
Admir
The price is RM498
RM573 total
includes taxes & fees
26 Jul - 27 Jul
Drury Inn & Suites St. Louis St. Peters

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1,007 reviews)
"Great family stay!"
United States
Caleb
The price is RM603
RM699 total
includes taxes & fees
26 Jul - 27 Jul
Hyatt Place St. Louis/Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1,201 reviews)
"Incredible stay!!"
United States
Jessica
The price is RM555
RM644 total
includes taxes & fees
7 Jul - 8 Jul
Drury Plaza Hotel St. Louis Chesterfield

Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1,003 reviews)
"I was very comfortable. Great green spaces for my little dog. Breakfast was okay."
United States
Louise
The price is RM313
RM370 total
includes taxes & fees
27 Jul - 28 Jul
Comfort Inn & Suites St. Louis - O'Fallon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Top Defiance Hotel Reviews

More cheap stays in Defiance

Frequently asked questions

What's the best place to stay in Defiance?
Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and The Wildwood Hotel. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Offers an indoor pool, an outdoor pool and buffet. The Wildwood Hotel and Ameristar Casino Resort and Spa are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. A top sight in the area is Six Flags St. Louis. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. Additionally, you'll find Six Flags St. Louis in the area. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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