Defiance hotels from RM320
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15 Aug - 16 AugTomorrow
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21 Aug - 23 AugIn two weeks
28 Aug - 30 AugOur top choices for Defiance hotels
1. Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
Josh
RM321
RM379 total
includes taxes & fees
7 Sept - 8 Sept
2. Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHGO'Fallon
Sheria
RM413
RM487 total
includes taxes & fees
20 Aug - 21 Aug
3. TownePlace Suites by Marriott St. Louis Chesterfield
TownePlace Suites by Marriott St. Louis ChesterfieldChesterfield
Cindy
RM523
RM614 total
includes taxes & fees
28 Aug - 29 Aug
4. The Wildwood Hotel
The Wildwood HotelWildwood
Hailey
RM360
RM420 total
includes taxes & fees
24 Aug - 25 Aug
5. Comfort Inn & Suites Chesterfield - St. Louis
Comfort Inn & Suites Chesterfield - St. LouisChesterfield
Jessica
RM344
RM414 total
includes taxes & fees
23 Aug - 24 Aug
6. Residence Inn by Marriott O'Fallon
Residence Inn by Marriott O'FallonO'Fallon
Gerald
RM535
RM631 total
includes taxes & fees
29 Aug - 30 Aug
7. Staybridge Suites O'Fallon Chesterfield by IHG
Staybridge Suites O'Fallon Chesterfield by IHGO'Fallon
Norman
RM466
RM549 total
includes taxes & fees
31 Aug - 1 Sept
8. Courtyard by Marriott St. Louis Chesterfield
Courtyard by Marriott St. Louis ChesterfieldChesterfield
Nathan
RM431
RM501 total
includes taxes & fees
28 Aug - 29 Aug
9. Hilton Garden Inn St. Louis/O'Fallon MO
Hilton Garden Inn St. Louis/O'Fallon MOO'Fallon
Kassie
RM566
RM671 total
includes taxes & fees
23 Aug - 24 Aug
10. Hampton Inn & Suites St. Louis/Chesterfield
Hampton Inn & Suites St. Louis/ChesterfieldChesterfield
Karen E
RM449
RM522 total
includes taxes & fees
30 Aug - 31 Aug
11. Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis ChesterfieldChesterfield
Andrea T
RM531
RM616 total
includes taxes & fees
30 Aug - 31 Aug
12. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Holiday Inn Express & Suites St. Louis - Chesterfield by IHGChesterfield
NEBAHAT
RM454
RM528 total
includes taxes & fees
13 Sept - 14 Sept
13. Super 8 by Wyndham Eureka/Six Flags Nearby
Super 8 by Wyndham Eureka/Six Flags NearbyEureka
Rosa
RM274
RM320 total
includes taxes & fees
30 Aug - 31 Aug
14. Hyatt Place St. Louis/Chesterfield
Hyatt Place St. Louis/ChesterfieldChesterfield
Taylor
RM458
RM531 total
includes taxes & fees
13 Sept - 14 Sept
15. Comfort Inn Near Six Flags St. Louis
Comfort Inn Near Six Flags St. LouisPacific
David
RM390
RM446 total
includes taxes & fees
13 Sept - 14 Sept
16. Holiday Inn St. Louis West Six Flags by IHG
Holiday Inn St. Louis West Six Flags by IHGEureka
Rob
RM405
RM471 total
includes taxes & fees
14 Sept - 15 Sept
17. Residence Inn by Marriott St. Louis Chesterfield
Residence Inn by Marriott St. Louis ChesterfieldChesterfield
Tenisha
RM772
RM904 total
includes taxes & fees
23 Aug - 24 Aug
18. WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
Ellen
RM353
RM418 total
includes taxes & fees
17 Aug - 18 Aug
19. Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
Jimi
RM527
RM600 total
includes taxes & fees
20 Aug - 21 Aug
20. Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
Melanie
RM449
RM517 total
includes taxes & fees
30 Aug - 31 Aug
Stay near popular Defiance attractions
August A. Busch Memorial Conservation Area
8.6/10 (7 reviews)
This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
Photo by Pages of Travel
Chandler Hill Vineyards
7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
Historic Daniel Boone Home and Heritage Center
9.6/10 (4 reviews)
Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.
Sugar Creek Winery
8.0/10 (1 review)
Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.
Yellow Farmhouse Winery
This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.
Matson Hill Park Trailhead
Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendour.
Broemmelsiek Park
This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.
Hamburg Trail Trailhead
This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.
See all hotels in Defiance
Top Defiance Hotel Reviews
Hilton St. Louis Frontenac
10/10 Excellent
"clean"
The Wildwood Hotel
10/10 Excellent
"It was nice, it didn't smell when walking in. Breakfast was mid... not hot items like meat or anything ... you can make your own waffles tho so that was cool."
Drury Plaza Hotel St. Louis Creve Coeur
10/10 Excellent
"Great friendly place"
Hollywood Casino & Hotel St. Louis
10/10 Excellent
"Smell of fish in the hall outside room. Otherwise great."
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
10/10 Excellent
"This is a very nice, clean, affordable hotel. My family and I were very comfortable during our stay here. I will definitely stay here again in the future,"
Sonesta ES Suites St. Louis - Chesterfield
10/10 Excellent
"My husband and I travel across the country about 2 x year to visit our daughter. This Sonesta ES Suites is the one return place that weโve come back to. The space is awesome with a full refrigerator and plenty of room to spread out. The hotel is truly pet friendly and staff are great- not to mention that they have a great breakfast in the morning. The one challenge is finding a parking space next to our suite later at night."
Best Western Plus St. Louis West-Westport
10/10 Excellent
"Good location, although there needs to be clear signage to locate the property. I never saw a sign for the hotel and GPS wasnโt very helpful. Otherwise, my stay was very good. I appreciated the available laundry facilities."
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
10/10 Excellent
"There was plenty of parking, AC worked like a dream, the beds were super comfy, and the staff was so kind, patient, and helpful. The only thing we were sad about was the pool. It wasn't dirty, it just looked a little too green and we don't know why. We didn't ask or press the issue because honestly we were out of the hotel for most of the time we were there. It may have been perfectly fine. We saw someone else getting ready to get into it. We were going to be checking in really late and they accommodated us. We got down to breakfast late one day, and they patiently waited for us to finish. We stayed for two nights. We had one bedroom with two queen size beds and it did not feel like the four of us were on top of each other, there was so much space! Overall good experience!!"
More cheap stays in Defiance
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd Maryland Heights MO
RM278
RM322 total
18 Aug - 19 Aug
includes taxes & fees
4.4/10 (1,002 reviews)
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive O'Fallon MO
RM321
RM379 total
7 Sept - 8 Sept
includes taxes & fees
Best Western Plus St. Louis West-Westport
12220 Dorsett Rd Maryland Heights MO
RM379
RM439 total
6 Sept - 7 Sept
includes taxes & fees
Hampton Inn St. Charles St. Peters
3720 W Clay St St. Charles MO
RM399
RM458 total
30 Aug - 31 Aug
includes taxes & fees
Best Western Plus Fenton
1680 Fenton Business Park Ct Fenton MO
RM405
RM468 total
18 Aug - 19 Aug
includes taxes & fees
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
11 Arnage Boulevard Chesterfield MO
RM454
RM528 total
13 Sept - 14 Sept
includes taxes & fees
9/10 Wonderful! (1,001 reviews)
