Defiance hotels from RM293

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31 Dec - 1 Jan
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Our top choices for Defiance hotels

Exterior
WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
9.2 out of 10, Wonderful, (29)
"Super clean , quiet place "
United States
Phoenix
The price is RM360
RM427 total
includes taxes & fees
3 Jan - 4 Jan
WoodSpring Suites St Peters-OFallon
Exterior
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (852)
"Excellent location, very clean and comfortable, great hot breakfast, and amazing staff!"
United States
Shannon
The price is RM445
RM534 total
includes taxes & fees
4 Jan - 5 Jan
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1003)
"Very good place to stay"
United States
Jasur
The price is RM310
RM365 total
includes taxes & fees
19 Jan - 20 Jan
Sleep Inn & Suites O'Fallon MO - Technology Drive
Ballroom
The Wildwood Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1613)
"Wonderful hotel staff, lovely facility."
United States
Kelley
The Wildwood Hotel
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1001)
"very friendly staff and good location "
United States
Heather
The price is RM393
RM451 total
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn St. Charles St. Peters
Lobby
Quality Inn Foristell

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (914)
"The staff and breakfast were terrific."
United States
Kevin
The price is RM299
RM338 total
includes taxes & fees
4 Jan - 5 Jan
Quality Inn Foristell
Property amenity
Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.4 out of 10, Good, (1001)
"Nice place and nice people "
United States
Columbus
The price is RM306
RM351 total
includes taxes & fees
6 Jan - 7 Jan
Baymont by Wyndham Warrenton
Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very good, (1060)
"While the water constantly ran in the bathtub, the staff was amazing, the beds were comfy enough, the free breakfast was filling and checkout was easy. "
United States
jessica
The price is RM344
RM397 total
includes taxes & fees
4 Jan - 5 Jan
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Courtyard
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Maryland Heights
7.4 out of 10, Good, (1001)
"Facilities were nice and spacious. Plenty of room for friends/relatives to visit. "
United States
Walt
The price is RM289
RM335 total
includes taxes & fees
15 Jan - 16 Jan
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Premium bedding, desk, iron/ironing board, free cots/infant beds
Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very good, (1003)
"I'd stay at this place again. "
United States
Suzanne
The price is RM306
RM352 total
includes taxes & fees
8 Jan - 9 Jan
Super 8 by Wyndham St Charles
Lobby
Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1001)
"The room was clean. The beds were comfortable. The lady at the front desk had a smile and was nice. Hot coffee available 24 hours a day. Well lighted property, I’m traveling with my two dachshunds. I would stay here again if I came through here. "
United States
Cindy Laine
The price is RM315
RM371 total
includes taxes & fees
18 Jan - 19 Jan
Comfort Inn & Suites St. Louis - O'Fallon
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (849)
"A very nice stay with very pleasant staff"
United States
Clifford
The price is RM368
RM435 total
includes taxes & fees
4 Jan - 5 Jan
Holiday Inn Express St. Louis West - O'Fallon by IHG
Lobby sitting area
Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
O'Fallon
8.8 out of 10, Excellent, (720)
"Clean room, quiet"
United States
Laura
The price is RM380
RM451 total
includes taxes & fees
23 Jan - 24 Jan
Hilton Garden Inn St. Louis/O'Fallon MO
Free daily buffet breakfast
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1001)
"Everything was great!"
United States
Rita
The price is RM427
RM490 total
includes taxes & fees
25 Jan - 26 Jan
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Best Western Plus Fenton

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (185)
"Good hotel. Room clean. Breakfast great. Price perfect!"
United States
gary
The price is RM373
RM430 total
includes taxes & fees
4 Jan - 5 Jan
Best Western Plus Fenton
Exterior
Best Western Plus Washington Hotel

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.0 out of 10, Wonderful, (640)
"What a great hotel! Spacious room, comfortable bed, great shower amenities and delicious breakfast!"
United States
Michelle
The price is RM522
RM595 total
includes taxes & fees
7 Jan - 8 Jan
Best Western Plus Washington Hotel
Lobby
Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport
2.5 star property
Maryland Heights
8.0 out of 10, Very good, (1039)
"The room was great and the bed was very comfortable "
United States
Joyce
The price is RM341
RM395 total
includes taxes & fees
12 Jan - 13 Jan
Best Western Plus St. Louis West-Westport
Lobby
Economy Inn Wentzville

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
Wentzville
6.4 out of 10, (511)
"The room was dirty so dirty we left didn't spend the night there, and the smell in the building weed or something else not sure which, it was ridiculous so we went to Hannibal and stayed at the Days inn "
United States
paul
The price is RM243
RM276 total
includes taxes & fees
2 Jan - 3 Jan
Economy Inn Wentzville
Front of property
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
Chesterfield
8.0 out of 10, Very good, (1030)
"Clean room,Friendly staff, Good location and Good Breakfast options"
United States
Micheal
The price is RM352
RM409 total
includes taxes & fees
6 Jan - 7 Jan
Sonesta ES Suites St. Louis - Chesterfield
In-room safe, desk, laptop workspace, blackout curtains
Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (622)
"Room was clean. Staff very helpful, accommodating. "
United States
Ranata
The price is RM248
RM284 total
includes taxes & fees
8 Jan - 9 Jan
Super 8 by Wyndham Warrenton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
See properties
Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
See properties

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"From check-in to check-out the staff was extremely professional, friendly, and courteous. The room was fabulous. It was clean and so spacious. A sunken sitting area was an added bonus. We had a view of the river and the bridge. My expectations were definitely exceeded. The only thing that was frustrating was the internet coverage. Our Internet was very limited. I had to go elsewhere to get a good Internet signal. I only had LTE coverage. "
Frances 1-night trip
Posted 3 days ago
Ameristar Casino Resort and Spa

More cheap stays in Defiance

Relax Inn Saint Charles

Relax Inn Saint Charles

3800 Harry S Truman Blvd St. Charles MO
The price is RM255 per night from 2 Jan to 3 Jan
RM255
RM293 total
2 Jan - 3 Jan
includes taxes & fees
6.6/10 (1,003 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Ameristar Casino Resort and Spa and The Wildwood Hotel. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. Ameristar Casino Resort and Spa and The Wildwood Hotel are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station and Busch Stadium. In Defiance, there are 20 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at Matson Hill Park Trailhead, August A. Busch Memorial Conservation Area and Missouri River. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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