Hotels in Medical Center District, San Antonio

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center District hotels

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,019 reviews)
"Clean room, friendly staff, convenient location and affordable "
United States
Sheila
The price is RM467
RM555 total
includes taxes & fees
16 May - 17 May
San Antonio Marriott Northwest Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,002 reviews)
"Very comfortable, everything was clean, great staff and it’s near all the important hospitals. "
United States
Jesus
The price is RM391
RM457 total
includes taxes & fees
26 Apr - 27 Apr
Fairfield Inn & Suites by Marriott San Antonio Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,287 reviews)
"Hotel was clean , and staff were very friendly. "
United States
Alyssa
The price is RM351
RM415 total
includes taxes & fees
21 Apr - 22 Apr
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,000 reviews)
"Great stay. Clean. Perfect location in Medical Center. "
United States
Carlos
The price is RM387
RM458 total
includes taxes & fees
2 May - 3 May
Courtyard by Marriott Medical Center San Antonio

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (999 reviews)
"The staff was couteous and the bed waa clean and comfortable. It was a quiet environment with a peaceful night of sleep."
United States
Melinda
Motel 6 San Antonio, TX - Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,301 reviews)
"Close to the medical facilities "
United States
Keith
The price is RM356
RM420 total
includes taxes & fees
3 May - 4 May
Drury Inn & Suites San Antonio Northwest Medical Center

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,003 reviews)
"courteous and accommodating staff. clean room, easy parking and proximity to medical facility. "
United States
Mary Louise
The price is RM265
RM310 total
includes taxes & fees
8 May - 9 May
Park Inn by Radisson

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (231 reviews)
"Excellent property!! Staff were very kind."
United States
Archie
The price is RM201
RM254 total
includes taxes & fees
2 May - 3 May
OYO Inn & Suites Medical Center San Antonio

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (274 reviews)
"The facility is clean, accesible and the staff is kind and helpful. Near to the medical center. "
United States
Yolanda
The price is RM185
RM216 total
includes taxes & fees
22 Apr - 23 Apr
Studio 6 San Antonio, Tx - Northwest Medical Center

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (523 reviews)
"It was a comfortable stay. No roaches or bed bugs at affordable prices "
United States
FrankR
The price is RM167
RM198 total
includes taxes & fees
26 Apr - 27 Apr
Flex Studios

Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (863 reviews)
"Good location for medical visit."
United States
jose
The price is RM198
RM242 total
includes taxes & fees
19 Apr - 20 Apr
Studio 6 Extended Stay - San Antonio, TX - Medical Center

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.6 out of 10, Good, (289 reviews)
"Excellent price, area is quite, close to Mays Clinic."
United States
Carol
The price is RM172
RM201 total
includes taxes & fees
19 May - 20 May
Atria Inn & Suites

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,001 reviews)
"Great place , front desk are helpful and friendly. Safe place to stay ."
United States
Justin
The price is RM242
RM282 total
includes taxes & fees
10 May - 11 May
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Hampton Inn & Suites Schertz

Hampton Inn & Suites Schertz
2.5 star property
31.1 km from Medical Center District
8.8 out of 10, Excellent, (873 reviews)
"The room was clean and affordable "
United States
Tamara
The price is RM317
RM365 total
includes taxes & fees
13 May - 14 May
Hampton Inn & Suites Schertz

Best Western Plus Atrium Inn

Best Western Plus Atrium Inn
2.5 star property
30.6 km from Medical Center District
8.6 out of 10, Excellent, (1,000 reviews)
"Clean amenities and a well stocked breakfast in the morning."
United States
Ben
The price is RM357
RM410 total
includes taxes & fees
29 Apr - 30 Apr
Best Western Plus Atrium Inn

Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
29.4 km from Medical Center District
9.2 out of 10, Wonderful, (260 reviews)
"Great parking, calm area and very friendly staff. Would definitely stay again. "
United States
Denise
The price is RM391
RM450 total
includes taxes & fees
21 Apr - 22 Apr
Extended Stay America Premier Suites - San Antonio - Schertz

stayAPT Suites San Antonio-Randolph

stayAPT Suites San Antonio-Randolph
2.5 star property
Live Oak, 24.4 km from Medical Center District
8.8 out of 10, Excellent, (523 reviews)
"The staff was amazing and so attentive to our needs!! "
United States
Kaylee
The price is RM352
RM404 total
includes taxes & fees
19 Apr - 20 Apr
stayAPT Suites San Antonio-Randolph

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown, 21.2 km from Medical Center District
8.2 out of 10, Very good, (1,003 reviews)
"Friendly Staff, easily find location,"
United States
Hua
The price is RM286
RM333 total
includes taxes & fees
5 May - 6 May
Best Western Garden Inn

La Quinta Inn & Suites by Wyndham San Antonio Alamo City

La Quinta Inn & Suites by Wyndham San Antonio Alamo City
3.0 star property
19.3 km from Medical Center District
8.2 out of 10, Very good, (1,001 reviews)
"Greeted with a smile and friendly patient service, air conditioning In room was perfect, all amenities and furniture were in great condition and well kept, lots of restaurant options within 10-15 min or less drive"
United States
Ramiro
The price is RM352
RM411 total
includes taxes & fees
26 Apr - 27 Apr
La Quinta Inn & Suites by Wyndham San Antonio Alamo City

Drury Inn & Suites San Antonio Northeast

Drury Inn & Suites San Antonio Northeast
3.0 star property
17.6 km from Medical Center District
9.4 out of 10, Exceptional, (1,003 reviews)
"This was exactly what I needed from my stay. Breakfast and dinner included with stay. Near major highway for easy transportation."
United States
Marlon
The price is RM356
RM408 total
includes taxes & fees
3 May - 4 May
Drury Inn & Suites San Antonio Northeast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,301 reviews
View
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,002 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,019 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,000 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,287 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include San Antonio Marriott Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 122 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

Explore a world of travel with Expedia