Top Motels in Pike County in 2026

A calm river surrounded by dense trees reflecting the greenery.

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Our top choices for Pike County motels

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

1. Motel 6 Hannibal, MO

Hannibal

Donna B

RM273 total

includes taxes & fees

19 Oct - 20 Oct

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

2. Super 8 by Wyndham Hannibal

Hannibal

Betty

RM291 total

includes taxes & fees

22 Oct - 23 Oct

A gazebo with a table and benches, surrounded by trees and a body of water.

3. River's Edge Motel

Louisiana

RM385 total

includes taxes & fees

11 Oct - 12 Oct

4. Brady Hotel

New Florence

Scott

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Top Pike County Hotel Reviews

Days Inn by Wyndham Hannibal

10/10 Excellent

"Everything was 5 star rating except the coffee from the automatic coffee dispenser."

Bay Inn & Suites Troy

8/10 Good

"Exceptionally clean, it actually appeared to be new. My only issue was the breakfast because the ‘hot’ items were cool at best. However there was a fairly good variety of cold options such as bananas, pre-packaged muffins 2 flavors) and cold cereal. Several beverages including orange, apple and grapefruit juice in a dispenser as well as coffee. There was also a waffle maker. Very nice set-up and would have easily been a 5 star across the board if the hot bar was actually hot."