Uptown

Collinsville

Uptown
Uptown

Popular places to visit

Things to do


Top hotels in Uptown

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is RM402 per night from 19 Apr to 20 Apr
RM402
RM470 total
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,131 reviews)
Amazing breakfast, great staff. The breakfast was superbly run. Customized omelettes. Enjoyed the updated moen shower.

Reviewed on 4 Apr 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is RM456 per night from 19 Apr to 20 Apr
RM456
RM533 total
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the restaurant in their ...
8.8/10 Excellent! (1,921 reviews)
Breakfast was ok...didnt go in the hot tub

Reviewed on 4 Apr 2026

Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is RM685 per night from 19 Apr to 20 Apr
RM685
RM801 total
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (3,354 reviews)
Clean roon

Reviewed on 4 Apr 2026

Drury Plaza Hotel St. Louis at the Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is RM641 per night from 6 Apr to 7 Apr
RM641
RM770 total
6 Apr - 7 Apr
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (1,721 reviews)
This hotel took me by surprise with how fancy it was! The museum was so cool, the room was very upscale, and the restaurant and cafe were so good! Friendly staff and overall a great experience. My only gripe is that they didn’t have stairs easily accessible as an alternative to the elevators. One ...

Reviewed on 4 Apr 2026

21C Museum Hotel St Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundable
The price is RM614 per night from 3 May to 4 May
RM614
RM723 total
3 May - 4 May
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (3,995 reviews)
The staff were very friendly and accommodating m. The hotel was great as always, lots of amenities, and great food choices. Breakfast is delicious, it is pricey but well worth the money.

Reviewed on 4 Apr 2026

Hyatt Regency St. Louis at The Arch
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
The price is RM581 per night from 19 Apr to 20 Apr
RM581
RM691 total
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,345 reviews)
The food was great, the staff was nice. We felt great the whole time we were there. The hotel is undergoing repairs and updating parts, so it was under construction, but glad to see improvements are being made. Our room furnace broke and we were getting heat only in there, it was hot. Then we were ...

Reviewed on 31 Mar 2026

Drury Inn & Suites St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown

early morning Cityscape of St. Louis skyline in Missouri state

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and Splash City Family Waterpark.

Historic Downtown Collinsville
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Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and FanDuel Sportsbook and Horse Racing.

Mulberry Hills


Uptown