Best Boutique Hotels in South Carolina Midlands

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on South Carolina Midlands Boutique Hotels

Top South Carolina Midlands Boutique Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in South Carolina Midlands

Lobby
Tru By Hilton Santee

Tru By Hilton Santee

2.5 star property
Santee
9.2 out of 10, Wonderful, (604)
"Nice place to stay"
Canada
Tanya
The price is RM430
RM477 total
includes taxes & fees
11 Dec - 12 Dec
Tru By Hilton Santee
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1149)
"Enjoyed our stay there. "
United States
Cathy
The price is RM421
RM472 total
includes taxes & fees
13 Dec - 14 Dec
Comfort Inn & Suites Florence Center Area
Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
9.8 out of 10, Exceptional, (1005)
"Very welcoming, hotel has a clean and friendly presentation."
Canada
VALERIE AND JOHN
The price is RM483
RM536 total
includes taxes & fees
7 Dec - 8 Dec
Fairfield Inn & Suites by Marriott Santee
Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

2.5 star property
Latta
9.4 out of 10, Exceptional, (523)
"Clean and beautiful, very friendly staff "
United States
claudia
The price is RM465
RM507 total
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express & Suites Latta by IHG
Front of property – evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property
Florence
8.8 out of 10, Excellent, (1003)
"Great stay"
United States
Michaelle
The price is RM416
RM466 total
includes taxes & fees
1 Dec - 2 Dec
Hyatt Place Florence Downtown
Exterior
Hampton Inn Newberry-Opera House

Hampton Inn Newberry-Opera House

2.5 star property
Newberry
8.8 out of 10, Excellent, (781)
"Was a nice hotel in a cute little town. Would stay there again!"
United States
Reuben
The price is RM341
RM379 total
includes taxes & fees
10 Dec - 11 Dec
Hampton Inn Newberry-Opera House
Free daily self-service breakfast
Lexington Expo Hotel by IHG

Lexington Expo Hotel by IHG

3.0 star property
Lexington
9.2 out of 10, Wonderful, (1000)
"Room was great staff was great"
United States
Stephen
The price is RM435
RM483 total
includes taxes & fees
20 Dec - 21 Dec
Lexington Expo Hotel by IHG
Lobby
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1007)
"Staff was friendly, room was clean and quiet. recommend this property."
United States
Janet
The price is RM430
RM477 total
includes taxes & fees
15 Dec - 16 Dec
Tru by Hilton Orangeburg
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property
Florence
9.0 out of 10, Wonderful, (2189)
"Friendly and efficient staff and a nice room for my overnight stay."
United States
Carole
The price is RM391
RM438 total
includes taxes & fees
7 Dec - 8 Dec
Park Inn by Radisson Florence, SC
Terrace/patio
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3.0 star property
West Columbia
9.0 out of 10, Wonderful, (1007)
"Great place to stay. "
United States
Melonie
The price is RM429
RM467 total
includes taxes & fees
20 Dec - 21 Dec
Hilton Garden Inn Columbia Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South Carolina Midlands Hotel Reviews

Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

10/10 Excellent
"Friendly staff and closeness to campus. "
Kristen 2-night trip
Posted 4 days ago
Graduate by Hilton Columbia SC

Explore a world of travel with Expedia