An abandoned, dilapidated wooden house surrounded by overgrown vegetation and leafless trees.

Best Boutique Hotels in Central United States

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Central United States Boutique Hotels

Tonight
7 Sept - 8 Sept
Tomorrow
8 Sept - 9 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

Our top choices for Central United States boutique hotels

A hotel entrance with a classic facade, an American flag, and a sign for Hotel Blake Chicago.
A hotel entrance with a marquee, American flag, and a person standing in front.
A hotel entrance with a marquee and string lights above the entrance.

1. Hilton Vacation Club Hotel Blake Chicago

Hilton Vacation Club Hotel Blake Chicago
Downtown Chicago
United States
Ann
RM1,045
RM1,242 total
includes taxes & fees
10 Sept - 11 Sept
Hilton Vacation Club Hotel Blake Chicago
A corridor with ornate black metal railings and a patterned carpet.
A dining area with tables and chairs, a hanging light fixture, and a view of the street through a window.
A bed with a pillow featuring a pineapple design and the text "Sleep with me." A window reveals a cityscape at night.
A modern hotel room with a sofa, a small table, a bench, a TV, and a cabinet.

2. Staypineapple, An Iconic Hotel, The Loop

Staypineapple, An Iconic Hotel, The Loop
Downtown Chicago
Canada
Jennifer
RM822
RM1,098 total
includes taxes & fees
27 Sept - 28 Sept
Staypineapple, An Iconic Hotel, The Loop
A hotel bathroom with a large mirror, a sink, and a vanity.
A gym with various exercise equipment, including treadmills and weight machines.
A bakery display with pastries and a coffee shop sign in the background.
A hotel room with a view of a cityscape through a large window, a floor lamp, a sofa with cushions, and a small table with a plant.

3. Sports Illustrated Resorts Chicago

Sports Illustrated Resorts Chicago
Downtown Chicago
United States
Jose Rafael
RM836
RM1,109 total
includes taxes & fees
9 Sept - 10 Sept
Sports Illustrated Resorts Chicago
A room with two chairs and a small table, a large window with a city view at night.
A modern living room with a sectional sofa, a round ottoman, a dining area with chairs and a table, and a large mirror on the wall.
A bar area with a long counter, multiple stools, and a television screen.
A modern hotel lobby with a large window, seating area, and a reception desk.

4. Eurostars Magnificent Mile

Eurostars Magnificent Mile
Downtown Chicago
United States
Brennique
RM809
RM962 total
includes taxes & fees
9 Sept - 10 Sept
Eurostars Magnificent Mile
A building with a sign reading "111" and "III West Adams Street" indicating a pub and restaurant.
A person sitting on a couch with a laptop, reading a book, in a room with a large window and a framed picture on the wall.
A modern lobby with leather sofas, a wooden coffee table, a TV mounted on the wall, and a bookshelf.
A hotel room with a large bed, a TV, a desk, and a chair.

5. Central Loop Hotel

Central Loop Hotel
Downtown Chicago
United States
Yiyang
RM689
RM819 total
includes taxes & fees
27 Sept - 28 Sept
Central Loop Hotel
A modern bar area with a marble countertop, leather bar stools, a chandelier, and a wall-mounted TV.
A modern hotel with a glass facade, multiple floors, and a prominent entrance with a purple-lit canopy.
A hotel room with a large bed, a desk with a lamp, a TV, and a bathroom visible through an open door.
A modern lobby with a sofa, armchairs, and a table. A large window offers a view of the street.

6. Ivy Boutique Hotel

Ivy Boutique Hotel
Downtown Chicago
United States
Jerry
RM842
RM988 total
includes taxes & fees
20 Sept - 21 Sept
Ivy Boutique Hotel
An outdoor rooftop lounge with seating, a fire feature, and a view of the city skyline at night.
A modern lounge area with leather sofas, wooden coffee tables, and ambient lighting.
A modern lobby with a wooden ceiling, leather sofas, and a coffee bar.
The Chicago Hotel Collection building with a glass facade, American flag, and signage for Barista Bar and Seighity events.

7. The Chicago Hotel Collection - Magnificent Mile

The Chicago Hotel Collection - Magnificent Mile
Downtown Chicago
United States
Patricia
RM461
RM548 total
includes taxes & fees
10 Sept - 11 Sept
The Chicago Hotel Collection - Magnificent Mile
A hotel room with a large bed, two armchairs, a desk, and a view of a cityscape through large windows.
A modern hotel room with a city view, a dining area with a table and chairs, and a large potted plant.
A hotel room with a large window, a dining area with a table and chairs, a sofa, a TV, and a decorative light fixture.
A spacious lobby with a glass entrance, escalators, and a tiled floor.

8. The Buckingham Hotel

The Buckingham Hotel
Downtown Chicago
United States
Ibrahim
RM735
RM920 total
includes taxes & fees
10 Sept - 11 Sept
The Buckingham Hotel
A bar area with a long counter, bar stools, and a mirrored wall.
A restaurant with wooden flooring, long tables, and chairs with patterned upholstery.
A luxurious lobby with a grand fireplace, elegant seating arrangements, and classic wood paneling.
A luxurious bathroom with a large oval bathtub, a chandelier, and two large mirrors with floral arrangements.

9. The Whitehall Hotel, BW Premier Collection

The Whitehall Hotel, BW Premier Collection
Downtown Chicago
Canada
Jerrad
RM623
RM740 total
includes taxes & fees
9 Sept - 10 Sept
The Whitehall Hotel, BW Premier Collection
A street view with outdoor seating, a green awning, and a sign for 'The Talbott'.
A hotel entrance with a marquee sign, outdoor seating, and a well-lit facade.
A lobby with a checkered floor, seating area, and a glass entrance.
A dining area with a long table, chairs, and a fireplace. There are framed pictures on the walls and a large flat-screen TV mounted on the wall.

10. The Talbott, Autograph Collection

The Talbott, Autograph Collection
Downtown Chicago
United States
Justin
RM1,129
RM1,487 total
includes taxes & fees
13 Sept - 14 Sept
The Talbott, Autograph Collection
View all properties

Top Central United States Hotel Reviews

River Hotel

River Hotel

10/10 Excellent
"Great service at check in."
Diana 1-night trip
Posted 1 hour ago
River Hotel
Hilton Chicago

Hilton Chicago

10/10 Excellent
"great location"
NILIANG 3-night trip
Posted 2 hours ago
Hilton Chicago
Gaylord Opryland Resort & Convention Center

Gaylord Opryland Resort & Convention Center

10/10 Excellent
"Great room"
Michael 2-night trip
Posted 3 hours ago
Gaylord Opryland Resort & Convention Center
The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast

10/10 Excellent
"We didn’t use the pool, but the hotel lounge and breakfast were nice. Parking was close $40 for a valet lot a block and half away. The staff was very nice and the room was clean and really comfortable."
Jennifer 1-night trip
Posted 3 hours ago
The Chicago Hotel Collection Ambassador Gold Coast
The Westin New Orleans

The Westin New Orleans

10/10 Excellent
"Great location, awesome view, great drinks👍"
Roberto 2-night trip
Posted 3 hours ago
The Westin New Orleans
Riverwalk Plaza

Riverwalk Plaza

10/10 Excellent
"👍"
Roy 1-night trip
Posted 3 hours ago
Riverwalk Plaza
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

10/10 Excellent
"Great play to stay, close to stadiums"
Adrian 1-night trip
Posted 4 hours ago
Club Quarters Hotel Downtown, Houston

Explore a world of travel with Expedia