Luxury Holidays in Northeast Missouri 2026

Photo by Andrew Hershfeld

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The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

6 min drive from St. Louis Union Station

Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, an outdoor pool and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...

9/10 Wonderful! (1,007 reviews)

"I had an outstanding stay at The Royal Sonesta Chase Park Plaza in St. Louis, Missouri. From the moment I arrived, the staff was welcoming, professional, and attentive, making me feel like a valued guest. The hotel was beautiful, clean, and well maintained, with a perfect blend of historic charm ..."

Reviewed on 6 Aug 2026

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

34 min drive from St. Louis Union Station

Stay at this luxury hotel in St. Charles. Enjoy a full-service spa, 6 restaurants and a casino. Our guests praise the clean rooms in their reviews. Popular attractions ...

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

13 min drive from St. Louis Union Station

Stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the room service ...

See all 3,024 properties in Northeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.