Luxury Holidays in Northeast Missouri 2026

Photo by Andrew Hershfeld

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The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

6 min drive from St. Louis Union Station

Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, an outdoor pool and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...

9.2/10 Wonderful! (1,006 reviews)

"The poll is the best! Gorgeous property"

Reviewed on 22 Sept 2026

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

34 min drive from St. Louis Union Station

Stay at this luxury hotel in St. Charles. Enjoy a full-service spa, 6 restaurants and a casino. Our guests praise the clean rooms in their reviews. Popular attractions ...

8.6/10 Excellent! (1,061 reviews)

"The smell was so bad, it made me sick. I had a terrible headache from it. It smelled like stale cigarettes. I will never star there again. So disappointed!!"

Reviewed on 20 Sept 2026

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

13 min drive from St. Louis Union Station

Stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the room service ...

9.2/10 Wonderful! (586 reviews)

"Don't eat at the restaurant. The food was awful. The service was horrible, maybe worst I've ever had. Couldn't get orders. Couldn't get refills. Server not once asked how the food or drinks were (they were awful as well). And it was an anniversary dinner for us and stay. Hotel pillows were horrible. ..."

Reviewed on 8 Sept 2026

See all 3,016 properties in Northeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.