Seneca Vacation Rentals

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Check prices for these dates

In two weeks
16 Jan - 18 Jan
In two months
27 Feb - 1 Mar
In three months
27 Mar - 29 Mar
In four months
24 Apr - 26 Apr

Our top choices for Seneca holiday rentals

Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (52)
"Excellent stay."
United States
Beonca
The price is RM360
RM575 total
includes taxes & fees
5 Jan - 6 Jan 2026
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas
Carolina Camp Cedar

Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
The price is RM389
RM806 total
includes taxes & fees
30 Dec - 31 Dec
Carolina Camp Cedar
Living room
Clemson Memorabilia House

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.8 out of 10, Exceptional, (9)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is RM360
RM962 total
includes taxes & fees
31 Dec - 1 Jan 2026
Clemson Memorabilia House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

10/10 Excellent
"The room was immaculate and very comfortable."
Shawn 1-night trip
Posted 2 days ago
Comfort Inn & Suites Clemson - University Area

Find out more about Seneca

Search for holiday rentals in Seneca on Expedia.co.uk! You can easily find your home rentals, villas, holiday apartments in Seneca using one of the methods below:

  • View our selection of featured holiday rentals in Seneca
  • Use the map to find apartments and other holiday homes in the Seneca neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Seneca while they last

Look no further and take a look at our great range of rental properties in Seneca!

Frequently asked questions

Are there holiday rentals in Seneca?

Yes, there are holiday rentals close to the most popular sights in Seneca, or you can select a more secluded option if you're looking for a relaxing stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffee shops.

How many holiday rentals are there in Seneca?

Choose from 201 Expedia holiday rentals in Seneca for a memorable holiday.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Keowee Reservoir and Lake Keowee are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Lake Hartwell are other places worth a visit.

What’s a holiday rental in Seneca like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Seneca. Holiday rentals offer extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a sanitised environment, a holiday rental can offer a sense of seclusion away from public hotel lifts and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is an attractive choice for family trips.