Weather will likely play an important role when you plan your trip to Santo Domingo, but bear in mind that cheaper options are usually available when the weather isn't as good. The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 24°C. The rainiest months in Santo Domingo are October, May, June and September, with each month seeing an average of 256 mm of rainfall.