Default HTG hotel image

Hotels near Santa Fe River

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Filter by

Star rating

Guest rating

Our top choices for Santa Fe River hotels

A modern kitchen area with a central counter, various food stations, and a chalkboard menu.
Fitness facility
A reception desk with a "Welcome to the Sun Shine State" sign, a "Treats" sign, and a minibar area with a "Hilton" sign.
A hotel room with two beds, a desk, a chair, a TV, and a couch.

1. Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
18 km from Santa Fe River
United States
Pamela
RM448
RM504 total
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Alachua I-75
A stone water feature with cascading water, surrounded by a brick wall and greenery.
A neatly arranged bedroom with a bed, bedside lamps, a TV, and a mirror.
A spacious living area with a wooden floor, a blue sofa, a round coffee table, and a ceiling fan.
A covered outdoor area with a paved walkway leading to a seating area, surrounded by greenery and a clear sky.

2. BlueGem Motel

BlueGem Motel
9.6 km from Santa Fe River
United States
Wesley
RM390
RM438 total
includes taxes & fees
6 Oct - 7 Oct
BlueGem Motel
A room with a wooden ceiling, two beds with patterned bedding, a desk, and a chair.
A small building with a green roof, a covered porch with wicker chairs, and a table.
A row of motel buildings with a fire hydrant and trees in front.
A bedroom with a bed, a chair, a dresser, a ceiling fan, a window with blinds, and a wall-mounted air conditioner.

3. High Springs Country Inn

High Springs Country Inn
9.4 km from Santa Fe River
United States
Luis
RM284
RM320 total
includes taxes & fees
11 Oct - 12 Oct
High Springs Country Inn
A hotel room with a bed, bedside tables, a desk, a chair, a mirror, and a window.
A reception area with a counter, a computer, and a bulletin board with pamphlets.
A bathroom with a large mirror, a sink, and a towel rack.
A corner room with two checkered chairs, a small table, a framed picture on the wall, and a floor lamp.

4. Palms Garden Inn

Palms Garden Inn
20.3 km from Santa Fe River
United States
Igor
RM282
RM317 total
includes taxes & fees
5 Oct - 6 Oct
Palms Garden Inn
A modern cafe with a counter, coffee machines, and seating.
A hotel room with a large bed, a chair, and a wall mural of a field.
A room with a black leather sofa set, a glass coffee table, and a large black and white mural depicting a street scene.
A modern hotel room with a wooden desk, a black office chair, a flat-screen TV mounted above the desk, and a coffee machine on the desk.

5. Clarion Pointe Alachua - Gainesville Area

Clarion Pointe Alachua - Gainesville Area
18.7 km from Santa Fe River
United States
María Teresa
RM246
RM297 total
includes taxes & fees
29 Oct - 30 Oct
Clarion Pointe Alachua - Gainesville Area
A swimming pool with a metal ladder, surrounded by a white fence and green chairs.
A refrigerated display case with beverages and snacks, and a shelf with bottled water and other beverages.
A hotel room with a patterned carpet, a sofa, a small table, a lamp, and a door with a notice.
A hotel room with a bed, a sofa, a coffee table, and a small table with a lamp.

6. Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
51.2 km from Santa Fe River
United States
Ana Laura
RM382
RM430 total
includes taxes & fees
16 Oct - 17 Oct
Best Western Waldo Inn and Suites
A hotel room with two beds, a desk, a chair, and a television.
A bathroom with a white sink, mirror, and towel rack.
A large, empty parking lot with marked parking spaces and a few trees in the background.
A parking lot with marked lanes and a grassy area on one side.

7. Royal Inn

Royal Inn
17.9 km from Santa Fe River
United States
Alec
RM265
RM298 total
includes taxes & fees
4 Oct - 5 Oct
Royal Inn
A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.
A spacious lobby with a dining area, a kitchen, and a large window providing a view of the outdoors.
A swimming pool with lounge chairs and umbrellas, a covered seating area, and a multi-story building with balconies.
A hotel room with a bed, a desk with a chair, a television, a mirror, and a wardrobe.

8. Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
18.6 km from Santa Fe River
United States
Deborah
RM310
RM349 total
includes taxes & fees
27 Oct - 28 Oct
Quality Inn Alachua - Gainesville Area
A hotel room with a bed, bedside lamps, a nightstand, a mirror, a bathroom with a sink and a bathtub.
A rectangular pool with a depth of 3 feet 2 inches, surrounded by a white fence and a building with a red roof in the background.
A motel with a sign for 'America's Best Value by Vantage Inn'.
A bathroom with a bathtub, a sink, and a mirror.

9. Americas Best Value Inn Starke

Americas Best Value Inn Starke
58.4 km from Santa Fe River
United States
Jeanette
RM434
RM482 total
includes taxes & fees
5 Oct - 6 Oct
Americas Best Value Inn Starke
A swimming pool with a white fence, palm trees, and a building with balconies in the background.
A hotel room with two beds, orange walls, a window with curtains, and a door with a lock.
A hotel corridor with a covered balcony, palm trees, and a lawn.
A hotel reception area with a modern design, featuring a reception desk, a coffee station, and a view of the outdoors.

10. Motel 6 Starke, FL

Motel 6 Starke, FL
58.5 km from Santa Fe River
United States
Anita
RM186
RM207 total
includes taxes & fees
4 Oct - 5 Oct
Motel 6 Starke, FL
A hotel room with a bed, a bathroom with a sink and mirror, and a view of the outdoors.
A hotel room with a bed, a bathroom with a sink and mirror, a wooden chair, and a television.
A motel with a parking lot, a staircase leading to the entrance, and a large tree in front.
A reception area with a desk, chairs, a clock, and a bulletin board.

11. Travelers Inn

Travelers Inn
38.8 km from Santa Fe River
United States
William
RM265
RM299 total
includes taxes & fees
4 Oct - 5 Oct
Travelers Inn
A covered outdoor seating area with a round wooden table, white wicker chairs, and a black grill.
A living room with a fireplace, a ceiling fan, a television, and a sofa.
A dining area with a round wooden table, four chairs, and a window with curtains.
A bedroom with a bed, a ceiling fan, a window with curtains, a painting, a bathroom door, a small table with a lamp, and a blue chair.

12. < 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
23.3 km from Santa Fe River
United States
Karen
RM588
RM1,581 total
includes taxes & fees
6 Oct - 7 Oct
< 1 Mi From Suwannee River, Hideaway w/ Lanai
A room with two beds, a TV, and a door.
A covered corridor with a row of parked cars on one side and a building with blue trim on the other.
A hotel room with a bed, a TV mounted on the wall, a remote control on a table, and a door leading to another room.
A bathroom with a toilet, sink, and mirror.

13. Soho Inn Waldo

Soho Inn Waldo
51.5 km from Santa Fe River
United States
Keith
RM221
RM248 total
includes taxes & fees
11 Oct - 12 Oct
Soho Inn Waldo
A clear blue swimming pool with a metal safety fence, surrounded by a building with multiple windows and balconies.
A hotel room with a wooden headboard, a colorful striped bedspread, two bedside lamps, a framed picture on the wall, and a small bedside table with a phone.
A hotel room with two beds, each with a patterned bedspread. There are two wall-mounted lamps on the nightstand between the beds.
A hotel room with two beds, a bedside table with a lamp, and a painting on the wall.

14. Red Carpet Inn

Red Carpet Inn
58.3 km from Santa Fe River
United States
Mark
RM282
RM313 total
includes taxes & fees
11 Oct - 12 Oct
Red Carpet Inn
A compact hotel room with a kitchenette, a dining area, a sofa, and large windows.
A hotel room with two beds, a desk, a television, and a lamp.
A reception area with a counter, a computer, a fan, and a registration sign.
A room with a desk, a computer, a fan, and various potted plants.

15. Campus Inn by Hotel O Gainesville - University Area

Campus Inn by Hotel O Gainesville - University Area
38.8 km from Santa Fe River
United States
Matthew
RM221
RM255 total
includes taxes & fees
6 Oct - 7 Oct
Campus Inn by Hotel O Gainesville - University Area
A gazebo with a tiled roof, surrounded by stone pillars and palm trees.
A modern restaurant with a blue wave-patterned wall, a self-service beverage station, and a variety of food items displayed.
A conference room with two desks, two chairs, and two monitors.
A reception area with a modern design, featuring a reception desk, a blue patterned wall, and a glass door leading outside.

16. Best Western Starke

Best Western Starke
58.7 km from Santa Fe River
United States
Christopher
RM425
RM472 total
includes taxes & fees
29 Oct - 30 Oct
Best Western Starke
A hotel room with a large bed, two bedside tables, a nightstand, a painting on the wall, and a window with a curtain.
A hotel room with a large bed, a nightstand, a lamp, a painting on the wall, and a window with curtains.
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.
A hotel room with two beds, a desk, and a chair.

17. Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
17.9 km from Santa Fe River
United States
Jennifer
RM259
RM292 total
includes taxes & fees
16 Oct - 17 Oct
Americas Best Value Inn Alachua
A kitchen with a sink, a microwave, and cabinets.
A bedroom with a bed, curtains, a painting, and a lamp.
A room with a patterned sofa, a green door with a decorative glass panel, and a framed picture on the wall.
A compact kitchen with a green countertop, a patterned sofa, and a wall-mounted light fixture.

18. The Humming Bird Suite - Affordable Lakefront Fun

The Humming Bird Suite - Affordable Lakefront Fun
63.2 km from Santa Fe River
RM327
RM503 total
includes taxes & fees
11 Oct - 12 Oct
The Humming Bird Suite - Affordable Lakefront Fun
Interior
A two-story building with a covered porch and a staircase leading to the upper level.
Interior
Interior

19. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
26.9 km from Santa Fe River
RM1,315
RM2,477 total
includes taxes & fees
4 Oct - 5 Oct
Suwannee River Retreat: Pet Friendly, Private Dock
A covered outdoor seating area with chairs and tables, overlooking a body of water and trees.
A beach with a table and chairs under an umbrella, a dock, and a boat in the background.
A room with a sofa, a chandelier, a cabinet, and large windows.
A kitchen with wooden cabinets, a marble island, and a bar area with stools.

20. Private Beach & Dock! North Florida Lake House

Private Beach & Dock! North Florida Lake House
64 km from Santa Fe River
RM1,213
RM2,489 total
includes taxes & fees
5 Oct - 6 Oct
Private Beach & Dock! North Florida Lake House
View all properties

Compare popular hotels close to Santa Fe River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern kitchen area with a central counter, various food stations, and a chalkboard menu.
Hampton Inn & Suites Alachua I-75
9.4
Exceptional
567 reviews
View
A stone water feature with cascading water, surrounded by a brick wall and greenery.
BlueGem Motel
9.2
Wonderful
478 reviews
View
A room with a wooden ceiling, two beds with patterned bedding, a desk, and a chair.
High Springs Country Inn
8.6
Excellent
48 reviews
View
A hotel room with a bed, bedside tables, a desk, a chair, a mirror, and a window.
Palms Garden Inn
7.6
Good
648 reviews
View
A modern cafe with a counter, coffee machines, and seating.
Clarion Pointe Alachua - Gainesville Area
7.6
Good
16 reviews
View

Top Santa Fe River Hotel Reviews

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

10/10 Excellent
"Nice clean hotel"
Timothy 1-night trip
Posted 4 days ago
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
High Springs Country Inn

High Springs Country Inn

10/10 Excellent
"While maybe not plush, the rooms are clean, staff friendly and helpful and the place well maintained. I stay here for a week or so every couple of months or so. It's a good value that is convenient to stores."
Patrick 9-night trip
Posted 2 weeks ago
High Springs Country Inn

Other attractions near Santa Fe River

An underwater scene with rocky formations and clear water.

Ginnie Spring

8.6/10 (51 reviews)
Commune with nature and explore the great outdoors at Ginnie Spring during your travels in High Springs. Amble around the area's parks or visit its shops.
See properties
A person swimming in clear blue water with visible underwater rocks and coral formations.
Photo by Laurie Karner

Ruth B. Kirby Gilchrist Blue Springs State Park

9.4/10 (52 reviews)
You can take time to visit Ruth B. Kirby Gilchrist Blue Springs State Park during your travels to High Springs. Discover the area's restaurants or seek out the kayaking spots.
See properties

Ichetucknee Conservation Area

You can take time to visit Ichetucknee Conservation Area during your travels to Branford. Make some time to visit the shops while you're in the area.
See properties

McCall Park

Explore the great outdoors at McCall Park, a lovely green space in High Springs. Amble around the area's parks or visit its shops.
See properties

Columbia Rise

Commune with nature and explore the great outdoors at Columbia Rise during your travels in High Springs. Amble around the area's parks or visit its shops.
See properties

High Springs Library Branch

High Springs Library Branch is just one of the places to see in High Springs, so why not enjoy the other things to explore during your travels? Amble around the area's parks or visit its shops.
See properties

High Springs Museum

You can spend an afternoon studying the exhibits at High Springs Museum during your travels in High Springs. Amble around the area's parks or visit its shops.
See properties

Frequently asked questions

What's the area like around Santa Fe River?
If you're planning to come to the area to visit Santa Fe River, take some time to see the rest of the sights while you're in town. This family-friendly area is known for its array of dining options and sporting events. You'll find 31 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Santa Fe River?
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy is one of the top choices for your stay based on our traveller data, and this cabin offers free parking and private patios. You'll find it 5.2 mi (8.3 km) from Santa Fe River. Other good options in the area include Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and BlueGem Motel.
How many hotels can I expect to find close to Santa Fe River?
Expedia has 31 hotels and other accommodation options a few miles from Santa Fe River.
If I need to cancel the hotel reservation for my stay near Santa Fe River, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get top deals close to Santa Fe River.