Hotels near Santa Fe River

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Our top choices for Santa Fe River hotels

Exterior
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
8.3 km from Santa Fe River
10.0 out of 10, Exceptional, (160)
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is RM341
RM731 total
includes taxes & fees
5 Jan - 6 Jan 2026
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Reception
BlueGem Motel

BlueGem Motel

BlueGem Motel
2.0 star property
9.6 km from Santa Fe River
9.2 out of 10, Wonderful, (395)
"Great place to stay."
United States
Wesley
The price is RM371
RM418 total
includes taxes & fees
14 Jan - 15 Jan 2026
BlueGem Motel
Laptop workspace, free WiFi
High Springs Country Inn

High Springs Country Inn

High Springs Country Inn
2.0 star property
9.4 km from Santa Fe River
8.2 out of 10, Very good, (17)
"Great remodel of a retro motel."
United States
Kathleen
The price is RM317
RM357 total
includes taxes & fees
14 Jan - 15 Jan 2026
High Springs Country Inn
Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
17.6 km from Santa Fe River
9.4 out of 10, Exceptional, (1001)
"Great stay. Good breakfast. "
United States
Bob
The price is RM474
RM533 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
18 km from Santa Fe River
9.4 out of 10, Exceptional, (476)
"Good overnight experience on a car trip. Nice staff."
United States
Luis
The price is RM428
RM482 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hampton Inn & Suites Alachua I-75
Desk, laptop workspace, blackout curtains, iron/ironing board
Alachua Inn

Alachua Inn

Alachua Inn
2.0 star property
18.7 km from Santa Fe River
5.8 out of 10, (658)
"Staff was very nice"
United States
Nekia
The price is RM250
RM301 total
includes taxes & fees
4 Jan - 5 Jan 2026
Alachua Inn
Desk, blackout curtains, iron/ironing board, rollaway beds
Americas Best Value Inn Alachua

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
17.9 km from Santa Fe River
4.8 out of 10, (599)
"Staff was helpful and so courteous.."
United States
Christian
The price is RM258
RM290 total
includes taxes & fees
8 Jan - 9 Jan 2026
Americas Best Value Inn Alachua
Outdoor pool
Travelers Inn

Travelers Inn

Travelers Inn
2.0 star property
38.8 km from Santa Fe River
6.4 out of 10, (402)
"Older property "
United States
Russell
The price is RM300
RM337 total
includes taxes & fees
14 Jan - 15 Jan 2026
Travelers Inn
Lobby sitting area
Motel 6 Starke, FL

Motel 6 Starke, FL

Motel 6 Starke, FL
2.0 star property
58.5 km from Santa Fe River
6.0 out of 10, (698)
"Rooms were clean & comfortable. Staff is also friendly "
United States
Rogers
The price is RM219
RM244 total
includes taxes & fees
4 Jan - 5 Jan 2026
Motel 6 Starke, FL
Free daily continental breakfast
Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
2.5 star property
18.5 km from Santa Fe River
7.2 out of 10, Good, (1004)
"The staff was very friendly, efficient and I thoroughly enjoyed my stay. "
United States
Darlene
The price is RM303
RM341 total
includes taxes & fees
26 Jan - 27 Jan 2026
Quality Inn Alachua - Gainesville Area
Premium bedding, desk, blackout curtains, soundproofing
Palms Garden Inn

Palms Garden Inn

Palms Garden Inn
2.0 star property
20.3 km from Santa Fe River
7.4 out of 10, Good, (581)
"Clean and nice staff "
United States
apollo
The price is RM263
RM296 total
includes taxes & fees
14 Jan - 15 Jan 2026
Palms Garden Inn
Lobby
Campus Inn by Hotel O Gainesville - University Area

Campus Inn by Hotel O Gainesville - University Area

Campus Inn by Hotel O Gainesville - University Area
2.5 star property
38.8 km from Santa Fe River
4.4 out of 10, (228)
"Hotel is what you expect, a low cost room in an old hotel in a college town. Two miles north of the stadium, an acceptable stagger back to the room after a Gator's victory."
United States
Steve
The price is RM283
RM319 total
includes taxes & fees
2 Jan - 3 Jan 2026
Campus Inn by Hotel O Gainesville - University Area
Desk, laptop workspace, iron/ironing board, free WiFi
Soho Inn Waldo

Soho Inn Waldo

Soho Inn Waldo
2.0 star property
51.5 km from Santa Fe River
The price is RM283
RM319 total
includes taxes & fees
14 Jan - 15 Jan 2026
Soho Inn Waldo
Outdoor pool
Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
51.2 km from Santa Fe River
8.8 out of 10, Excellent, (954)
"Nice room, hot breakfast, friendly and helpful staff."
United States
Anne
The price is RM413
RM465 total
includes taxes & fees
7 Jan - 8 Jan 2026
Best Western Waldo Inn and Suites
Free daily full breakfast
Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
56.4 km from Santa Fe River
9.6 out of 10, Exceptional, (425)
"Rooms and service was great "
United States
Josh
The price is RM385
RM427 total
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Express Starke by IHG
Outdoor pool
Americas Best Value Inn Starke

Americas Best Value Inn Starke

Americas Best Value Inn Starke
2.0 star property
58.4 km from Santa Fe River
7.4 out of 10, Good, (535)
"Yes pet friendly, parking was good and well lighted "
United States
Rex
The price is RM506
RM562 total
includes taxes & fees
4 Jan - 5 Jan 2026
Americas Best Value Inn Starke
Exterior
Best Western Starke

Best Western Starke

Best Western Starke
2.5 star property
58.6 km from Santa Fe River
8.6 out of 10, Excellent, (667)
"staff was great but construction was noisy."
United States
Duane
The price is RM321
RM356 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Starke
Seasonal outdoor pool
Red Carpet Inn

Red Carpet Inn

Red Carpet Inn
2.0 star property
58.3 km from Santa Fe River
8.6 out of 10, Excellent, (623)
"clean room and attentive staff"
United States
Scott
The price is RM279
RM310 total
includes taxes & fees
4 Jan - 5 Jan 2026
Red Carpet Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Fe River Hotel Reviews

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"The cabins were extremely clean. Great place to getaway… can’t wait to go back! Such a cute setup… Great location for exploring state parks. No complaints personally… perfect getaway whether alone or with someone A++++"
gilberto 1-night trip
Posted 7 days ago
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Hotels near other Santa Fe River attractions

Blue waters of the spring basin drop down to the rocky cavern entrance at Ginnie Ballroom, Ginnie Springs, Florida

Ginnie Spring

Commune with nature and explore the great outdoors at Ginnie Spring during your travels in High Springs. Amble around the area's parks or visit its shops.
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My boyfriend Joe went for an early morning swim in the springs. We were camping in the park for the weekend. I took this from the jumping platform.
Photo by Laurie Karner
Open Photo by Laurie Karner

Ruth B. Kirby Gilchrist Blue Springs State Park

4.6/5 (40 reviews)
You can take time to visit Ruth B. Kirby Gilchrist Blue Springs State Park during your travels to High Springs. Discover the area's restaurants or seek out the kayaking spots.
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Frequently asked questions

What's the area like around Santa Fe River?
If you're planning to come to the area to visit Santa Fe River, take some time to see the rest of the sights while you're in town. This family-friendly area is known for its array of dining options and sporting events. You'll find 24 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Santa Fe River?
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy is one of the top choices for your stay based on our traveller data, and this cabin offers free parking and private patios. You'll find it 5.2 mi (8.3 km) from Santa Fe River. Other good options in the area include Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and BlueGem Motel.
How many hotels can I expect to find close to Santa Fe River?
Expedia has 24 hotels and other accommodation options a few miles from Santa Fe River.
If I need to cancel the hotel reservation for my stay near Santa Fe River, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get top deals close to Santa Fe River.