Hotels in Santa Ana, Antigua Guatemala

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Check prices for these dates

Tonight
8 Mar - 9 Mar
Tomorrow
9 Mar - 10 Mar
Next weekend
13 Mar - 15 Mar
In two weeks
20 Mar - 22 Mar

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Our top choices for Santa Ana hotels

Front of property

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (51 reviews)
"Great place !!"
United States
Abner Israel Polanco
The price is RM259
RM316 total
includes taxes & fees
9 Mar - 10 Mar
Casa Buho B&B
Front of property

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.8 out of 10, Excellent, (13 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
Villas Santa Ana-Ricardo
Garden view

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (23 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is RM188
RM229 total
includes taxes & fees
24 Mar - 25 Mar
Hostal Casa Buho
Outdoor pool

Hotel Posada del Angel

Hotel Posada del Angel
4.0 star property
1 km from Santa Ana
9.6 out of 10, Exceptional, (286 reviews)
"We had a great stay! The hotel is a very charming boutique hotel nestled in Antigua. The room was very comfortable and we were able to rest very well. The staff was always very helpful and friendly. "
United States
Janelle
Hotel Posada del Angel
Banquet hall

Pensativo House Hotel

Pensativo House Hotel
4.5 star property
1 km from Santa Ana
9.4 out of 10, Exceptional, (404 reviews)
"Rooms were clean and bed and pillows were comfortable with good A/C. Staff was very helpful and were always ready to assist. Food was excellent. "
United States
Carlos Alvarez
Pensativo House Hotel
Exterior

Meson Panza Verde

Meson Panza Verde
3.5 star property
1.1 km from Santa Ana
9.2 out of 10, Wonderful, (450 reviews)
"This was the most amazing hotel we stayed in Antigua! Absolutely beautiful and comfortable! Staff was always very friendly and helpful. Restaurant had amazing atmosphere and food. Will definitely be returning! "
United States
Janelle
The price is RM702
RM857 total
includes taxes & fees
25 Mar - 26 Mar
Meson Panza Verde
Courtyard

Hotel Genessis

Hotel Genessis
3.5 star property
0.9 km from Santa Ana
9.2 out of 10, Wonderful, (110 reviews)
"Gorgeous gorgeous hotel! Staff was so friendly! Will definitely stay here again!"
United States
Sandy
Hotel Genessis
Exterior

San Rafael Hotel

San Rafael Hotel
4.0 star property
Historic Center, 1.5 km from Santa Ana
9.8 out of 10, Exceptional, (451 reviews)
"Great room"
United States
Steven
The price is RM829
RM1,023 total
includes taxes & fees
9 Mar - 10 Mar
San Rafael Hotel
Terrace/patio

Casa Noble Hotel

Casa Noble Hotel
3.0 star property
0.9 km from Santa Ana
9.6 out of 10, Exceptional, (192 reviews)
"Very nice place!"
Canada
Zaul
Casa Noble Hotel
Courtyard

Hotel Las Marías

Hotel Las Marías
3.0 star property
1.9 km from Santa Ana
9.2 out of 10, Wonderful, (438 reviews)
"clean room in a good area"
United States
roghayeh
The price is RM351
RM428 total
includes taxes & fees
15 Mar - 16 Mar
Hotel Las Marías
Exterior

Naif Boutique Hotel

Naif Boutique Hotel
3.0 star property
Historic Center, 1.4 km from Santa Ana
9.0 out of 10, Wonderful, (404 reviews)
"We had a great stay! Very comfortable and nice."
United States
Janelle
Naif Boutique Hotel
Garden

Hotel Cacique Real

Hotel Cacique Real
3.0 star property
1.8 km from Santa Ana
8.8 out of 10, Excellent, (173 reviews)
"A beautiful hotel that’s in a nice location that isn’t far from all the main tourist attractions but is also slightly calmer than the main high streets. The staff were all really helpful and friendly and the breakfast was great."
United Kingdom
Magdalene
Hotel Cacique Real
Hallway

Hotel Las Farolas

Hotel Las Farolas
3.5 star property
1.2 km from Santa Ana
9.2 out of 10, Wonderful, (728 reviews)
"It is relatively close and walkable to the central plaza and all amenities around it."
United States
helmuth
Hotel Las Farolas
Reception

EL TEJAR HOSTAL

EL TEJAR HOSTAL
3.0 star property
21 km from Santa Ana
8.4 out of 10, Very good, (19 reviews)
"Staff very friendly and helpful. Room clean and quiet. "
United States
ILEANA
The price is RM158
RM192 total
includes taxes & fees
10 Mar - 11 Mar
EL TEJAR HOSTAL
Living area

Indian Palace

Indian Palace
3.0 star property
2.8 km from Santa Ana
9.0 out of 10, Wonderful, (38 reviews)
"Beautiful view to the volcanics clean area Beautiful pool, good game room i will recommend."
United States
Estuardo
The price is RM313
RM382 total
includes taxes & fees
11 Mar - 12 Mar
Indian Palace
Garden

Hotel Aurora

Hotel Aurora
3.5 star property
Historic Center, 1.1 km from Santa Ana
9.6 out of 10, Exceptional, (397 reviews)
"The room was super clean, the staff was so nice. The breakfast was delicious and the hotel overall is in a great walking location."
United States
Mileyshka
The price is RM326
RM398 total
includes taxes & fees
10 Mar - 11 Mar
Hotel Aurora
Interior

Hotel Casa del Parque

Hotel Casa del Parque
3.5 star property
Historic Center, 1.4 km from Santa Ana
8.4 out of 10, Very good, (516 reviews)
"Everything was great, hotel stunning, beautiful,staff fantastic, location perfect"
United States
Terri
The price is RM770
RM939 total
includes taxes & fees
29 Mar - 30 Mar
Hotel Casa del Parque
Interior detail

Casa Santa Rosa Hotel Boutique

Casa Santa Rosa Hotel Boutique
3.5 star property
Historic Center, 1.4 km from Santa Ana
9.6 out of 10, Exceptional, (346 reviews)
"Best place to stay in Antigua!!"
United States
Maria
The price is RM620
RM756 total
includes taxes & fees
8 Apr - 9 Apr
Casa Santa Rosa Hotel Boutique
Garden view

Santo Cielo by Casa Santo Domingo

Santo Cielo by Casa Santo Domingo
3.5 star property
0.9 km from Santa Ana
9.4 out of 10, Exceptional, (532 reviews)
"Best stay I’ve ever had."
United States
Marco
The price is RM839
RM1,071 total
includes taxes & fees
9 Mar - 10 Mar
Santo Cielo by Casa Santo Domingo
Front of property

Why Not Hotel

Why Not Hotel
3.0 star property
Historic Center, 1.5 km from Santa Ana
8.4 out of 10, Very good, (156 reviews)
"Great location and great price. I would definitely stay here again. "
United States
DEBORAH
The price is RM191
RM233 total
includes taxes & fees
10 Mar - 11 Mar
Why Not Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.
Palacio de los Capitanes
Photo by Jacques Cramatte
Open Photo by Jacques Cramatte

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Best Western Plus Hotel Stofella

Best Western Plus Hotel Stofella

2/10 Terrible
"No se los recomiendo Los cuartos no tienen aire acondicionado y tienen chinche y al llegar nos cobraron extra muy mal servicio "
Irma Carolina 1-night trip
Posted 1 hour ago
Best Western Plus Hotel Stofella

Frequently asked questions

What's it like in Santa Ana?
Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favourite place to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking. Another top choice in the area is Hostal Casa Buho.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 15 hotels and other accommodation options in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.