Hotels in San Francisco, Panama City

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Check prices for these dates

Tonight
4 Mar - 5 Mar
Tomorrow
5 Mar - 6 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

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Our top choices for San Francisco hotels

2 bedrooms

Dovle 512 in Ciudad de Panam

Dovle 512 in Ciudad de Panam
2.0 star property
San Francisco
The price is RM679
RM747 total
includes taxes & fees
5 Mar - 6 Mar
Dovle 512 in Ciudad de Panam
4 outdoor pools, free pool cabanas, pool umbrellas

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
"Beautiful hotel, great service. Breakfast buffet is amazing. "
United States
Tamara
The price is RM965
RM1,061 total
includes taxes & fees
3 Apr - 4 Apr
JW Marriott Panama
TV

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is RM198
RM798 total
includes taxes & fees
5 Mar - 6 Mar
Living 73 Panamá by Boutique Apartments
Breakfast, lunch, dinner served; international cuisine

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,151 reviews)
"Clean, nice staff and super close to the airport "
United States
Leticia
The price is RM403
RM443 total
includes taxes & fees
1 Apr - 2 Apr
Ramada Plaza by Wyndham Panama Punta Pacifica
Daily buffet breakfast (PAB 21 per person)

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,003 reviews)
"Good locatiion"
United States
Caren
The price is RM527
RM579 total
includes taxes & fees
14 Mar - 15 Mar
Sheraton Grand Panama
Terrace/patio

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,138 reviews)
"Hotel was very clean, the staff was very helpful and the breakfast was very good!"
United States
Monty
The price is RM426
RM469 total
includes taxes & fees
5 Mar - 6 Mar
Plaza Paitilla Inn Hotel
Exterior

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (973 reviews)
"Perfect stay for a few days at Panama!"
United States
Maria
The price is RM467
RM513 total
includes taxes & fees
4 Apr - 5 Apr
Aloft Panama
Exterior

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,011 reviews)
"Overall stay was great..staff was super friendly"
United States
Bjorna
The price is RM466
RM513 total
includes taxes & fees
28 Mar - 29 Mar
Courtyard by Marriott Panama Multiplaza Mall
Front of property

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,586 reviews)
"Nice comfortable hotel and very friendly staff."
Canada
norah
The price is RM546
RM601 total
includes taxes & fees
8 Mar - 9 Mar
Decapolis Hotel Panama City
Outdoor pool

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is RM671
RM1,341 total
includes taxes & fees
1 Apr - 2 Apr
Wanders Panama by Boutique Apartments
1 bedroom

Dovle 510 in Ciudad de Panam

Dovle 510 in Ciudad de Panam
2.0 star property
San Francisco
8.0 out of 10, Very good, (1 review)
"Very clean and staff were friendly and welcoming."
United States
Steven
The price is RM498
RM548 total
includes taxes & fees
8 Mar - 9 Mar
Dovle 510 in Ciudad de Panam
Front of property

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,442 reviews)
"Clean room,helpful staff around the hotel,good food options"
United States
Umar
The price is RM953
RM1,048 total
includes taxes & fees
8 Mar - 9 Mar
Megapolis Hotel Panamá
Living area

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.6 out of 10, Good, (172 reviews)
"Clean room good place to stay "
United States
Gideon
The price is RM195
RM768 total
includes taxes & fees
1 Apr - 2 Apr
Boutique Apartments Panamá Coco del Mar
View from property

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,006 reviews)
"excellent room and location"
United States
Jon
The price is RM653
RM718 total
includes taxes & fees
1 Apr - 2 Apr
Las Americas Golden Tower Panama
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, pool loungers

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (576 reviews)
"Great location, friendly staff, clean rooms, very comfortable beds. "
United States
Sharna
The price is RM631
RM694 total
includes taxes & fees
3 Apr - 4 Apr
Residence Inn by Marriott Panama City
Free WiFi

Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
6.8 out of 10, (9 reviews)
"Very "
United States
Scott
The price is RM289
RM318 total
includes taxes & fees
16 Mar - 17 Mar
Casa Orquídea
Outdoor pool

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
7.8 out of 10, Good, (31 reviews)
"The place was clean nice an its comfortable an the view is to kill for amazing ‼️"
United States
Odaine
Boutique Apartments Atlapa
Outdoor pool

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
2.8 out of 10, (3 reviews)
"Inadequate heating in the pool , poor customer service. No hot water in the shower. It was a terrible experience but it’s a nice place, hopefully with better management can offer outstanding services "
United States
Herbert
The price is RM564
RM620 total
includes taxes & fees
5 Mar - 6 Mar
Dovle Residences by HMS-Preferred Member
2 bedrooms

Dovle 312 in Ciudad de Panam

Dovle 312 in Ciudad de Panam
2.0 star property
San Francisco
The price is RM683
RM751 total
includes taxes & fees
9 Mar - 10 Mar
Dovle 312 in Ciudad de Panam
2 bedrooms

Dovle 501 in Ciudad de Panam

Dovle 501 in Ciudad de Panam
2.0 star property
San Francisco
The price is RM679
RM747 total
includes taxes & fees
16 Mar - 17 Mar
Dovle 501 in Ciudad de Panam
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
Panama City view old casco viejo antiguo

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Nice building, highlight on Panama's skyline.
Photo by My World
Open Photo by My World

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

Panama City Old Town streets and buildings

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

sunset sky above Panama City - cityscape panorama view

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"This hotel was superb. The breakfast was excellent, with a wide variety of choices and a fantastic buffet selection. The entire staff, from check-in and reception to the servers and housekeeping, was extremely helpful and attentive. Many staff members spoke English and truly went above and beyond to make our stay enjoyable and comfortable. The only suggestion I would make is adding an additional pool to the property. The hotel is conveniently located, with many restaurants nearby, and a short Uber ride will take you just about anywhere. The area felt very safe, and overall, Panama is a wonderful and welcoming country. Great hotel and a great country, I would definitely recommend it."
Lyne 5-night trip
Posted 12 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 234 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Pacific Center might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.