What's it like in Potrero Hill?

Potrero Hill is a neighbourhood that travellers like for its architecture and live music. Looking for sights you might find in a travel guide about Potrero Hill? Consider a visit to San Francisco Bay while you're in the neighbourhood.

How many hotels can I expect to find in the Potrero Hill area?

When you want to put your feet up after a day of exploring the sights in San Francisco, you can choose from 15 Expedia hotels and other accommodation options in Potrero Hill.

If I need to cancel my hotel reservation in Potrero Hill, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals in Potrero Hill.

What can I see and do in this San Francisco neighbourhood?

Potrero Hill's sights and attractions like Letterform Archive, Museum of Craft & Design and Bottom of the Hill offer insight into the local culture. San Francisco Bay and Anchor Brewing Company are also a couple of places to visit in the neighbourhood. Oracle Park, The Midway and 888 Garage are just a few of the places to visit in and around Potrero Hill. When you're sightseeing in San Francisco, Chase Center and Pier 80 are also worth a stop.

How can I get around Potrero Hill and the greater San Francisco area?

For a quick way to explore the city, catch a ride on metro transit at 20th Street Station, 23rd Street Station or UCSF Medical Center Station. If you want to head out of town, you can hop aboard a train at 22nd Street Station.

Top 10 Potrero Hill Hotels of 2026

A busy urban street lined with parked cars and buildings, with a clear view of tall skyscrapers in the background.

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Our top choices for Potrero Hill hotels

An outdoor seating area with wicker furniture and a fire feature, adjacent to a bar and dining area with modern decor.

1. Hyatt Place San Francisco Downtown

2.3 km from Potrero Hill

Brittney

RM928 total

includes taxes & fees

1 Oct - 2 Oct

A spacious lobby with large windows, a seating area with a sofa and chairs, and a counter with a coffee station.

2. LUMA Hotel San Francisco

1.8 km from Potrero Hill

Jennifer

RM1,064 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with modern seating, a large abstract sculpture, and a high ceiling with linear lighting.

3. Hyatt Regency San Francisco

Financial District, 4 km from Potrero Hill

Juan

RM1,228 total

includes taxes & fees

18 Sept - 19 Sept

An indoor swimming pool with multiple lounge chairs and a high ceiling with skylights.

4. Hotel Nikko San Francisco

Union Square, 3.5 km from Potrero Hill

DORIS

RM1,108 total

includes taxes & fees

20 Sept - 21 Sept

A high-rise room with a city view, a sofa, two chairs, a small table, and a patterned rug.

5. Hilton San Francisco Union Square

Union Square, 3.5 km from Potrero Hill

Hector

RM816 total

includes taxes & fees

3 Oct - 4 Oct

A modern hotel lobby with a seating area, a bar, and large windows.

6. Hotel Riu Plaza Fisherman's Wharf

Fisherman's Wharf, 5.8 km from Potrero Hill

Nicole

RM955 total

includes taxes & fees

8 Sept - 9 Sept

A rooftop pool area with blue seating and a pool.

7. Holiday Inn Golden Gateway by IHG

Nob Hill, 4.5 km from Potrero Hill

Ella

RM724 total

includes taxes & fees

20 Sept - 21 Sept

A buffet counter with coffee machines, a TV, and various food items.

8. Stanyan Park Hotel

5.7 km from Potrero Hill

Amy

RM918 total

includes taxes & fees

8 Sept - 9 Sept

A white car parked in a modern indoor space with a circular ceiling, large windows, and potted plants.

9. Holiday Inn Express and Suites Fisherman's Wharf by IHG

Fisherman's Wharf, 5.9 km from Potrero Hill

Cindy Patricia

RM888 total

includes taxes & fees

8 Sept - 9 Sept

A rooftop terrace with a table and chairs, a potted plant, and a view of tall buildings.

10. Club Quarters Hotel Embarcadero, San Francisco

Financial District, 4.2 km from Potrero Hill

Kathleen

RM743 total

includes taxes & fees

20 Sept - 21 Sept

A lobby with seating, a reception desk, and large windows.

11. Chancellor Hotel on Union Square

3.7 km from Potrero Hill

Paul

RM569 total

includes taxes & fees

10 Sept - 11 Sept

An outdoor patio area with modern furniture, a fire feature, and a decorative metal sculpture.

12. Hotel Zoe Fisherman's Wharf

Fisherman's Wharf, 5.7 km from Potrero Hill

Lissa

RM948 total

includes taxes & fees

8 Sept - 9 Sept

A hotel room with a large bed, a desk with a chair, a TV, and a view of the city.

13. Comfort Inn by the Bay

Cow Hollow, 5.6 km from Potrero Hill

Michael

RM656 total

includes taxes & fees

9 Sept - 10 Sept

A multi-level hotel atrium with outdoor seating areas, a pool, and a central lounge.

14. Embassy Suites by Hilton San Francisco Airport Oyster Point

11.5 km from Potrero Hill

jenny

RM697 total

includes taxes & fees

2 Oct - 3 Oct

A hotel with a modern design, featuring a prominent 'PARC 55' sign, a 'Barbary Coach' restaurant, and a view of the street with light trails from moving vehicles.

15. Parc 55 San Francisco - A Hilton Hotel

Union Square, 3.4 km from Potrero Hill

Eric

RM777 total

includes taxes & fees

2 Oct - 3 Oct

A multi-story hotel with a prominent sign reading "The Handlebar Union Square Hotel."

16. Handlery Union Square Hotel

Union Square, 3.6 km from Potrero Hill

Andrea

RM696 total

includes taxes & fees

20 Sept - 21 Sept

A hotel entrance with a sign reading "HOTEL FIONA," a parking garage, and a red brick facade.

17. Hotel Fiona

South of Market, 2.9 km from Potrero Hill

Takara

RM536 total

includes taxes & fees

11 Sept - 12 Sept

A pool area with lounge chairs and umbrellas.

18. Hotel Caza Fisherman´s Wharf

Fisherman's Wharf, 5.9 km from Potrero Hill

William

RM919 total

includes taxes & fees

8 Sept - 9 Sept

A spacious lobby with a reception desk, seating area, and a staircase leading to an upper level.

19. Hotel Triton Union Square San Francisco

Union Square, 3.8 km from Potrero Hill

Pragya

RM689 total

includes taxes & fees

18 Sept - 19 Sept

A modern interior with round tables and chairs, a patterned rug, and a large wooden wall.

20. Hotel Zelos San Francisco

South of Market, 3.3 km from Potrero Hill

Ross

RM1,092 total

includes taxes & fees

18 Sept - 19 Sept

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Where to stay in Potrero Hill

Find the best Potrero Hill areas for the activities you enjoy most.

A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

This waterfront location is steeped in history dating back to the days of the gold rush. Today, visitors come here for its vibrant atmosphere and great food.

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A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Packed with a treasure trove of upmarket boutiques, designer labels and department store, shoppers will love this huge shopping plaza.

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A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

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A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

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Top Potrero Hill Hotel Reviews

Hilton San Francisco Airport Bayfront

10/10 Excellent

"Nice location, clean"

FOUND Hotel Carlton, Nob Hill

10/10 Excellent

"Decent hotel in a very convent location for many downtown SF attractions. The hotel is on a quiet street but close to the Tenderloin and Polk street actions. Customer Service was nice and average, rooms were clean and simple, and the hotel seemed to be well maintained. I liked being able to open the windows for fresh air. Parking can be difficult but there are garages nearby."

Hotels in Potrero Hill, San Francisco

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Our top choices for Potrero Hill hotels

1. Hyatt Place San Francisco Downtown

2. LUMA Hotel San Francisco

3. Hyatt Regency San Francisco

4. Hotel Nikko San Francisco

5. Hilton San Francisco Union Square

6. Hotel Riu Plaza Fisherman's Wharf

7. Holiday Inn Golden Gateway by IHG

8. Stanyan Park Hotel

9. Holiday Inn Express and Suites Fisherman's Wharf by IHG

10. Club Quarters Hotel Embarcadero, San Francisco

11. Chancellor Hotel on Union Square

12. Hotel Zoe Fisherman's Wharf

13. Comfort Inn by the Bay

14. Embassy Suites by Hilton San Francisco Airport Oyster Point

15. Parc 55 San Francisco - A Hilton Hotel

16. Handlery Union Square Hotel

17. Hotel Fiona

18. Hotel Caza Fisherman´s Wharf

19. Hotel Triton Union Square San Francisco

20. Hotel Zelos San Francisco

Where to stay in Potrero Hill

Fisherman's Wharf

Union Square

Downtown San Francisco

South of Market

Nob Hill

Top Potrero Hill Hotel Reviews

Hilton San Francisco Airport Bayfront

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