A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Best Luxury Hotels in Panama City

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Check availability on Panama City Luxury Hotels

Tonight
19 Oct - 20 Oct
Tomorrow
20 Oct - 21 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Panama City luxury hotels

A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
RM1,433
RM1,576 total
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
A poolside area with lounge chairs and a view of the ocean.
A terrace with seating and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

2. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
RM1,140
RM1,254 total
includes taxes & fees
6 Nov - 7 Nov
JW Marriott Panama
A restaurant with multiple dining tables, chairs, and a central water feature.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.
A historic building with ornate stonework and a balcony with plants.
A bar area with multiple seating options, a bar counter, and a fireplace.

3. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
RM1,141
RM1,256 total
includes taxes & fees
21 Oct - 22 Oct
Hotel La Compañía Casco Antiguo
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.
A modern interior with a spiral staircase, a large window, and a seating area.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.

4. Hilton Panama

Hilton Panama
Bella Vista
  • Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
RM1,072
RM1,179 total
includes taxes & fees
8 Nov - 9 Nov
Hilton Panama
A hotel entrance with a central water feature, seating areas, and potted plants.
A pool with a central water feature, surrounded by seating areas and potted plants.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
The entrance of The Santa Maria with a covered walkway and a view of the interior.

5. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
RM1,275
RM1,402 total
includes taxes & fees
8 Nov - 9 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.

6. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
  • Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
RM1,072
RM1,179 total
includes taxes & fees
7 Nov - 8 Nov
Waldorf Astoria Panama
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a dining area, a TV, and a city view.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

7. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
  • Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
RM577
RM635 total
includes taxes & fees
25 Oct - 26 Oct
Hotel Riu Plaza Panama
A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A modern restaurant with checkered flooring, wooden chairs, and large windows offering a view of greenery.
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.

8. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
RM498
RM575 total
includes taxes & fees
5 Nov - 6 Nov
Crowne Plaza Panama Airport by IHG
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.

9. W Panama

W Panama
Bella Vista
  • Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
RM944
RM1,038 total
includes taxes & fees
1 Nov - 2 Nov
W Panama
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A spacious lobby with a tiled floor, large windows, and potted plants.
A white building with multiple balconies, large windows, and decorative railings.
A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.

10. American Trade Hotel

American Trade Hotel
Casco Viejo
  • A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalised service in a historic district.
RM1,003
RM1,103 total
includes taxes & fees
1 Nov - 2 Nov
American Trade Hotel
View all properties

Top Panama City Hotel Reviews

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

8/10 Good
"Great breakfast and central location. Staff was very welcoming."
Carolina 2-night trip
Posted 15 hours ago
Las Americas Golden Tower Panama

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 24 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Megapolis Hotel Panamá and Hyatt Regency Panama City are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 24 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Avenida Balboa.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina Station and Santo Tomás Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.