Hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.0 out of 10, Very good, (1,606 reviews)
"Great place to stay. Really clean and helpful staff "
Zulma
The price is RM440
RM500 total
includes taxes & fees
25 Jan - 26 Jan
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.0 out of 10, Good, (1,005 reviews)
"The room was nice the beds comfortable I’ll stay there again."
Leo
The price is RM400
RM454 total
includes taxes & fees
25 Jan - 26 Jan
The Bristol Hotel San Diego
The Bristol Hotel San Diego24.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,474 reviews)
"Newly remodeled rooms, clean and wonderful staff. "
Zoe
Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and MarinaMission Bay, 33.9 km from Otay Mesa
8.4 out of 10, Very good, (1,593 reviews)
"Balcony view is awesome, clean room, staff at counter and restaurant service was stunning."
francisco
The price is RM601
RM905 total
includes taxes & fees
25 Jan - 26 Jan
Paradise Point Resort & Spa
Paradise Point Resort & SpaMission Bay, 34.5 km from Otay Mesa
8.8 out of 10, Excellent, (2,382 reviews)
"This is a staple for me and my family whenever we are in the area."
Elizabeth
The price is RM581
RM883 total
includes taxes & fees
22 Feb - 23 Feb
Wyndham San Diego Bayside
Wyndham San Diego Bayside25.7 km from Otay Mesa
8.4 out of 10, Very good, (6,007 reviews)
"Great place to stay"
David
The price is RM616
RM856 total
includes taxes & fees
25 Jan - 26 Jan
Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San DiegoGaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1,003 reviews)
"Great location and stay. "
Simran
The price is RM359
RM533 total
includes taxes & fees
25 Jan - 26 Jan
Palihotel San Diego Gaslamp Quarter
Palihotel San Diego Gaslamp QuarterGaslamp Quarter, 24.5 km from Otay Mesa
8.6 out of 10, Excellent, (2,195 reviews)
"Excellent location, wonderful staff."
phuc
The price is RM504
RM585 total
includes taxes & fees
25 Jan - 26 Jan
Courtyard by Marriott San Diego Mission Valley/Hotel Circle
Courtyard by Marriott San Diego Mission Valley/Hotel Circle28.8 km from Otay Mesa
8.4 out of 10, Very good, (1,455 reviews)
"Nice location, confortable hotel"
Anna Maria
The price is RM521
RM598 total
includes taxes & fees
25 Jan - 26 Jan
The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection25.4 km from Otay Mesa
9.0 out of 10, Wonderful, (951 reviews)
"Great stay. Would definitely stay again."
Zoraima
The price is RM474
RM550 total
includes taxes & fees
22 Feb - 23 Feb
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 33.1 km from Otay Mesa
8.4 out of 10, Very good, (1,339 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
Dani
The price is RM746
RM1,072 total
includes taxes & fees
22 Feb - 23 Feb
Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1,682 reviews)
"Very clean resort. "
Petrina
The Dana on Mission Bay
The Dana on Mission BayMission Bay, 33.8 km from Otay Mesa
9.0 out of 10, Wonderful, (4,026 reviews)
"Great location, friendly attentive staff and great tv setup in rooms."
John
The price is RM642
RM830 total
includes taxes & fees
25 Jan - 26 Jan
Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (2,942 reviews)
"Great relaxing hotel"
Christopher
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,675 reviews)
"Great place"
Gustavo
The price is RM561
RM618 total
includes taxes & fees
25 Jan - 26 Jan
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp QuarterGaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1,257 reviews)
"Friendly staff, great location, excellent value overall "
Maryann
The price is RM642
RM745 total
includes taxes & fees
25 Jan - 26 Jan
Marriott Vacation Club®, San Diego
Marriott Vacation Club®, San Diego24.7 km from Otay Mesa
9.4 out of 10, Exceptional, (1,003 reviews)
"Great place to stay!"
Rose Marie JOy
The price is RM650
RM753 total
includes taxes & fees
15 Feb - 16 Feb
Moxy San Diego Downtown/Gaslamp Quarter
Moxy San Diego Downtown/Gaslamp QuarterGaslamp Quarter, 24.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,004 reviews)
"Amazing stay over all! Everything was great.
Staff was friendly.
"
Nancy
The price is RM460
RM570 total
includes taxes & fees
25 Jan - 26 Jan
The Sofia Hotel
The Sofia Hotel24.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,713 reviews)
"Clean rooms, and very nice staff"
Guadalupe
Gaslamp Plaza Suites
Gaslamp Plaza SuitesGaslamp Quarter, 24.6 km from Otay Mesa
9.0 out of 10, Wonderful, (1,025 reviews)
"Loved the staff very welcoming.
Room was good and comfortable.
Perfect location. This is our 3rd time here and definitely will come back. "
SONIA
The price is RM480
RM546 total
includes taxes & fees
25 Jan - 26 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Ocean Beach
With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.
