Hotels in Otay Mesa, San Diego

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Our top choices for Otay Mesa hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1,660 reviews)
"Clean, great breakfast, good service."
United States
Sara
The price is RM511
RM581 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,008 reviews)
"Great staff.. location close to the airport!"
United States
Vivian
The price is RM426
RM485 total
includes taxes & fees
5 Apr - 6 Apr
Quality Suites San Diego Otay Mesa

Westgate Hotel

Westgate Hotel
4.5 star property
24.9 km from Otay Mesa
9.2 out of 10, Wonderful, (1,018 reviews)
"Great stay"
United States
ESMERALDA
Westgate Hotel

Courtyard by Marriott Old Town

Courtyard by Marriott Old Town
3.0 star property
Old Town San Diego, 29.7 km from Otay Mesa
8.6 out of 10, Excellent, (1,003 reviews)
"Great place!!!"
United States
Hannah
The price is RM710
RM816 total
includes taxes & fees
22 Mar - 23 Mar
Courtyard by Marriott Old Town

Super 8 by Wyndham San Diego Hotel Circle

Super 8 by Wyndham San Diego Hotel Circle
2.0 star property
28.8 km from Otay Mesa
7.2 out of 10, Good, (718 reviews)
"Staff was great, the room was very clean."
Canada
Jennifer
The price is RM310
RM356 total
includes taxes & fees
19 Mar - 20 Mar
Super 8 by Wyndham San Diego Hotel Circle

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
30.1 km from Otay Mesa
8.6 out of 10, Excellent, (1,018 reviews)
"Super clean rooms and a great location "
United States
Mark
Sea Harbor Hotel

Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,193 reviews)
"Beds are super comfy clean and renovated"
United States
Esmeralda
Ocean Villa Inn

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1,003 reviews)
"Great location and stay. "
United States
Simran
The price is RM446
RM631 total
includes taxes & fees
6 Apr - 7 Apr
Staypineapple, Hotel Z, Gaslamp San Diego

Fairfield Inn & Suites San Diego Old Town

Fairfield Inn & Suites San Diego Old Town
3.0 star property
Old Town San Diego, 29.4 km from Otay Mesa
8.6 out of 10, Excellent, (1,012 reviews)
"Great location, clean rooms, good breakfast"
United States
Jingyi
The price is RM589
RM677 total
includes taxes & fees
5 Apr - 6 Apr
Fairfield Inn & Suites San Diego Old Town

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 25.8 km from Otay Mesa
8.6 out of 10, Excellent, (1,928 reviews)
"Great location and staff "
United States
morgan
La Pensione Hotel

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 26.7 km from Otay Mesa
8.4 out of 10, Very good, (1,000 reviews)
"Clean, very chill easy check in"
United States
Susana
The price is RM356
RM402 total
includes taxes & fees
15 Mar - 16 Mar
Berkshire Motor Hotel

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
25.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,015 reviews)
"Clean rooms, friendly staff, hotel close to eateries "
United States
Debbie
The price is RM555
RM642 total
includes taxes & fees
7 Apr - 8 Apr
Best Western Plus Bayside Inn

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
31.8 km from Otay Mesa
7.4 out of 10, Good, (1,316 reviews)
"Clean room, staff was great during check in and checking out. "
United States
Amber
The price is RM243
RM280 total
includes taxes & fees
24 Mar - 25 Mar
Heritage Inn San Diego

Porto Vista Hotel Downtown

Porto Vista Hotel Downtown
3.5 star property
Little Italy, 25.8 km from Otay Mesa
7.0 out of 10, Good, (1,249 reviews)
"Great location, friendly staff, dog friendly and nice rooms! "
United States
Chelsea
Porto Vista Hotel Downtown

The Beau Hotel Gaslamp Quarter San Diego

The Beau Hotel Gaslamp Quarter San Diego
3.0 star property
Gaslamp Quarter, 24.5 km from Otay Mesa
9.0 out of 10, Wonderful, (638 reviews)
"Clean room, friendly staff, great location."
United States
Bruce
The price is RM602
RM685 total
includes taxes & fees
6 Apr - 7 Apr
The Beau Hotel Gaslamp Quarter San Diego

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
29.3 km from Otay Mesa
9.2 out of 10, Wonderful, (2,821 reviews)
"Great stay, highly recommend."
United States
Ryan
The price is RM709
RM894 total
includes taxes & fees
5 Apr - 6 Apr
Humphreys Half Moon Inn

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 24.6 km from Otay Mesa
9.0 out of 10, Wonderful, (1,026 reviews)
"Clean quiet friendly helpful staff convenient location will stay there again"
United States
David
The price is RM491
RM559 total
includes taxes & fees
5 Apr - 6 Apr
Gaslamp Plaza Suites

Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
4.0 star property
28.2 km from Otay Mesa
8.6 out of 10, Excellent, (1,719 reviews)
"Great stay!"
United States
Linda
The price is RM535
RM615 total
includes taxes & fees
15 Mar - 16 Mar
Sheraton Mission Valley San Diego Hotel

Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego, 30.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,364 reviews)
"Great location, great price, nice hotel "
United States
Estela
The price is RM558
RM641 total
includes taxes & fees
15 Mar - 16 Mar
Hilton Garden Inn San Diego Old Town/SeaWorld Area

Ocean Beach Hotel

Ocean Beach Hotel
3.0 star property
Ocean Beach, 33.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,268 reviews)
"The hotel was a great environment and felt very safe and comfortable. "
United States
Charity
Ocean Beach Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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