Top 10 Northeast Missouri Hotels with Air Conditioning for 2026

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Check availability on Northeast Missouri Hotels with Air Conditioning

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Our top choices for Northeast Missouri hotels with air conditioning

Pillow-top beds, desk, blackout curtains, soundproofing

1. Depot Inn and Suites

La Plata

David

RM388

RM421 total

includes taxes & fees

28 Sept - 29 Sept

2. Super 8 by Wyndham Kirksville-University Area

Kirksville

David

RM275

RM309 total

includes taxes & fees

13 Sept - 14 Sept

3. Oak Hill Inn & Suites

Canton

Marie

RM409

RM467 total

includes taxes & fees

7 Sept - 8 Sept

In-room safe, desk, laptop workspace, blackout curtains

4. Holiday Inn Express & Suites Kirksville - University Area by IHG

Kirksville

Jimmy

RM445

RM504 total

includes taxes & fees

4 Oct - 5 Oct

Desk, iron/ironing board, free cots/infant beds, rollaway beds

5. Quality Inn & Suites Hannibal West

Hannibal

Tom

RM327

RM381 total

includes taxes & fees

4 Oct - 5 Oct

Iron/ironing board (on request), cots/infant beds, free WiFi, bed sheets

6. Travelier Motel

Macon

Jessica

RM255

RM303 total

includes taxes & fees

27 Sept - 28 Sept

Desk, iron/ironing board, WiFi, bed sheets

Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

7. Best Western On The River

Hannibal

Mark

RM445

RM513 total

includes taxes & fees

15 Sept - 16 Sept

Desk, iron/ironing board, free cots/infant beds, free WiFi

8. Sleep Inn & Suites Hannibal West

Hannibal

Patricia

RM478

RM556 total

includes taxes & fees

27 Sept - 28 Sept

View all properties

Top Northeast Missouri Hotel Reviews

Drury Inn & Suites St. Louis Airport

8/10 Good

"We enjoyed our stay. We found the staff to be very friendly and accommodating. The overall cleanliness of the hotel was great. The beds are comfortable and the AC was welcoming, given it was above 100 degrees every day during our stay. The breakfast was nice, I would have liked to see a little more verity for the hot breakfast each day. Maybe offer omelets and a different choice of breakfast meats in addition to the scrambled eggs and sausage patties. There was a griddle to make pancakes everyday, which could have been easily used to offer other options for eggs. But all in all, the food was fine. The dinner reception as well as drinks offered, was nice. We enjoyed having a hot meal option for a snack and not just chips and salsa. The hotel offers shuttle transportation to and from the airport, which is always a plus. We would definitely stay here again."

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent

"Very clean and staff was very polite and helpful"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Great value overall"

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"Our stay was nice. We like that there was a parking garage. Our room was accommodating and clean. The breakfast was good. And staff was pleasant."

Courtyard by Marriott St. Louis Downtown/Convention Center

10/10 Excellent

"Everything was super excellent"

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

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Frequently asked questions

How much do hotels with air conditioning in Northeast Missouri cost?

Rates for hotels with air conditioning in Northeast Missouri range between RM303 and RM616 per night. No matter your budget, you'll be sure to discover an awesome place to spend your holiday in air-conditioned comfort. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best hotels with air conditioning in Northeast Missouri?

Jump into holiday mode and wind down in one of Northeast Missouri's multiple hotels with air conditioning. With a total average guest review rating of 9.4, there's a place for every style and budget. Many visitors to St. Louis recommend a stay at Drury Inn & Suites St. Louis Brentwood, a highly rated 3-stars retreat with a swimming pool, front desk services and air conditioning. Another guest favourite here is Drury Plaza Hotel St. Louis at the Arch. This 3-stars escape offers a terrace and a swimming pool.

How many hotels with air conditioning are there in Northeast Missouri?

Take a peek at our 287 hotels with AC in Northeast Missouri and reserve your favourite. Whether you're embarking on a family escape or a weekend with friends, your perfect stay is just clicks away with Expedia.

What are the top motels with air conditioning in Northeast Missouri?

Booking motels with air conditioning is an economical way to enjoy a comfortable getaway in Northeast Missouri. Planning a day or two in St. Louis? Americas Best Value Inn St. Louis Downtown comes with blackout curtains and a nearby metro station and is a traveller fave. Located approximately 2 kilometers east of the bustling downtown area, you'll be within easy reach of all the action here. Guest Host Motel, about 3 kilometers northwest of central St. Louis, is another option offering air-conditioned comfort and amenities such as WiFi and front desk services.After some epic things to do in St. Louis? St. Louis Zoo and Forest Park are just a couple of the enticing attractions that pull in big crowds.

Are there any family-friendly hotels with air conditioning in Northeast Missouri?

You can book family-friendly hotels with air conditioning in locations across Northeast Missouri, including St. Louis. Drury Plaza Hotel St. Louis at the Arch is one property that'll fit your needs in this exciting city. It has a 3-stars rating and handy amenities like complimentary breakfast and WiFi. Alternatively, put down your bags at Drury Inn & Suites St. Louis Forest Park. With complimentary breakfast, a laundry service and AC, this 3-stars pick in St. Louis will make your team feel welcome and relaxed. There are plenty of fabulous things to do with your crew in St. Louis. St. Louis Zoo and Forest Park offer the perfect day out.

Are there any 5-star hotels with air conditioning in Northeast Missouri?

Book one of our 5-star hotels with air conditioning and enjoy a splurge on your Northeast Missouri holiday. If you're staying in St. Louis, take a look at Four Seasons Hotel St Louis. This 5-star retreat comes with the air-conditioned comfort you're looking for, together with concierge services and proposal/romance packages. You can also appreciate the best of everything at The Ritz-Carlton, St. Louis. Rooms with AC, designer toiletries and concierge services help make this a superb base to discover the vibes of St. Louis.

Why book your hotel with air conditioning in Northeast Missouri with Expedia?

Expedia has unbeatable deals on hotels with air conditioning in Northeast Missouri. If you need to stick to a budget, click on how much you want to spend and the preferred star rating of your hotel. Then make use of our filters to search for air-conditioned retreats with amenities like a hot tub or a swimming pool. We'll help you find the right place whatever your bank balance or plans.

How can I find cheap hotels with air conditioning in Northeast Missouri?

Expedia can help you locate cheap hotels with air conditioning in Northeast Missouri. Simply select the "air conditioned" box below the amenities filter to view stays with this feature. Then, choose your hotel star rating (lower-rated stays are easier on your hip pocket!) and your budget per night to find a suitable property with AC at the lowest price.

What is there to do in Northeast Missouri near my hotel with air conditioning?

The most important accessory for your Northeast Missouri holiday is a well-thought-out itinerary! Fox Theatre, Anheuser-Busch Brewery and St. Louis Aquarium at Union Station are some of the leading things to do if you're visiting St. Louis. Maryland Heights also has plenty of superb attractions, such as New Jewish Theatre. In the mood to explore more? Pencil in a visit to Hollywood Casino Amphitheatre and Payne-Gentry Historical House too.

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Northeast Missouri Hotels with Air Conditioning

Our top choices for Northeast Missouri hotels with air conditioning

1. Depot Inn and Suites

2. Super 8 by Wyndham Kirksville-University Area

3. Oak Hill Inn & Suites

4. Holiday Inn Express & Suites Kirksville - University Area by IHG

5. Quality Inn & Suites Hannibal West

6. Travelier Motel

7. Best Western On The River

8. Sleep Inn & Suites Hannibal West

9. Best Western Plus Washington Hotel

10. Pinemark Inn & Suites

Top Northeast Missouri Hotel Reviews

Drury Inn & Suites St. Louis Airport

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Clayton Plaza Hotel & Extended Stay

Pear Tree Inn St. Louis Near Union Station

Courtyard by Marriott St. Louis Downtown/Convention Center

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Frequently asked questions

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