Hotels near National Medical Center

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29 Dec - 30 Dec
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30 Dec - 31 Dec
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for National Medical Center (Siglo XXI) hotels

Private kitchen
ULIV Roma Norte

ULIV Roma Norte

ULIV Roma Norte
4.0 star property
Roma Norte, 0.8 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (306)
"Great location. Staff were very friendly and helpful"
United States
Blake
ULIV Roma Norte
Premium bedding, in-room safe, individually decorated
Ignacia Guest House

Ignacia Guest House

Ignacia Guest House
3.0 star property
Roma Norte, 0.9 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (88)
"This was easily my favorite stay while in CDMX. The home/lobby area was so beautifully designed, decorated, and spotlessly clean. The center garden area was lush, immaculately tended to, and so peaceful. Getting to enjoy my morning coffee from the balcony looking out at it was so relaxing. The breakfast was delicious and having their kind and talented staff cooking in the open kitchen next door was a lovely intimate touch to a home-cooked experience. I definitely plan on booking again if I’m...
United States
Emily
The price is RM1,122
RM1,408 total
includes taxes & fees
6 Jan - 7 Jan 2026
Ignacia Guest House
Minibar, in-room safe, individually decorated, free WiFi
Xoma Boutique Stays by Viadora

Xoma Boutique Stays by Viadora

Xoma Boutique Stays by Viadora
4.0 star property
Roma Norte, 1 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (162)
"We stayed in this hotel in December and absolutely loved it. It was clean, the staff was helpful and nice, the location was amazing. Close to a park, very quiet and easy to get around. Would absolutely stay here again!"
United States
Sara
The price is RM973
RM1,178 total
includes taxes & fees
20 Jan - 21 Jan 2026
Xoma Boutique Stays by Viadora
Living area
Casa Serenos

Casa Serenos

Casa Serenos
3.0 star property
Roma Sur, 1.3 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (10)
"Beautiful hotel in great location..kind and attentive staff. Felt very safe. Beautiful rooms!!"
Canada
Amrita
The price is RM703
RM840 total
includes taxes & fees
1 Jan - 2 Jan 2026
Casa Serenos
Free daily full breakfast
Casa Seis Siete

Casa Seis Siete

Casa Seis Siete
2.5 star property
Roma Norte, 1.3 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (48)
"Location is great, the staff even better!! "
United States
Martin
The price is RM1,640
RM1,960 total
includes taxes & fees
3 Jan - 4 Jan 2026
Casa Seis Siete
Egyptian cotton sheets, premium bedding, down duvets
Colima 71 Casa de Arte Hotel

Colima 71 Casa de Arte Hotel

Colima 71 Casa de Arte Hotel
3.0 star property
Roma Norte, 1.4 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (41)
"Excellent service and room, great area in town, small quiet hotel "
United States
Nader
The price is RM2,564
RM3,268 total
includes taxes & fees
4 Jan - 5 Jan 2026
Colima 71 Casa de Arte Hotel
Hallway
Hotel Escala Colonia Roma

Hotel Escala Colonia Roma

Hotel Escala Colonia Roma
2.0 star property
Roma Norte, 0.6 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (368)
"Clean room, nice , helpfull staff , geografical situation amazing"
United Kingdom
El abed
The price is RM185
RM221 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Escala Colonia Roma
Rooftop terrace
Lasai Casa Tonala

Lasai Casa Tonala

Lasai Casa Tonala
3.5 star property
Roma Norte, 1 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (23)
"It's a great place to stay and it's affordable. "
Canada
Vismaya
The price is RM358
RM570 total
includes taxes & fees
5 Jan - 6 Jan 2026
Lasai Casa Tonala
Fridge, microwave, oven, coffee/tea maker
OM686 Urban Lofts Short-Long Stays

OM686 Urban Lofts Short-Long Stays

OM686 Urban Lofts Short-Long Stays
3.0 star property
0.9 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (249)
"Very nice staff, comfortable bed, have stayed here twice and would return again"
United States
Drew
The price is RM277
RM335 total
includes taxes & fees
5 Jan - 6 Jan 2026
OM686 Urban Lofts Short-Long Stays
Free WiFi
RMS Hostal - Roma Norte

RMS Hostal - Roma Norte

RMS Hostal - Roma Norte
2.0 star property
Roma Norte, 1.2 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (9)
"Super central location and cozy vibes. "
United States
Aurélie
The price is RM79
RM94 total
includes taxes & fees
31 Dec - 1 Jan 2026
RMS Hostal - Roma Norte
Rooftop terrace
Casa Izeba

Casa Izeba

Casa Izeba
4.0 star property
Roma Norte, 1.5 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (78)
"Amazing staff, great location, and beautiful room/property."
Canada
Karen
The price is RM1,567
RM1,873 total
includes taxes & fees
5 Jan - 6 Jan 2026
Casa Izeba
Interior
Cuadra 134 Residencial Condesa

Cuadra 134 Residencial Condesa

Cuadra 134 Residencial Condesa
4.5 star property
Roma Norte, 1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (242)
"Clean, safe and walkable to many restaurants, coffee shops, and convenience stores. "
United States
Shavanna
The price is RM511
RM610 total
includes taxes & fees
25 Jan - 26 Jan 2026
Cuadra 134 Residencial Condesa
Smart TV, streaming services
Tanat Art Hotel

Tanat Art Hotel

Tanat Art Hotel
2.0 star property
Roma Sur, 1.4 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (135)
"The apartment is gorgeous, clean, and the bed very comfortable! The location is also very convenient😊 "
United Kingdom
Julia
Tanat Art Hotel
Rooftop terrace
TONALA by Mr. W

TONALA by Mr. W

TONALA by Mr. W
3.0 star property
Roma Norte, 1.2 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (30)
"Wonderful property in a a great location, lots of shops and restaurants within walking distance. Staff were available 24/7 at the front desk, which helped us to feel safe and the ladies working answered any questions we had. The apartment was spacious and had everything we needed (utensils, glassware, cookware, etc). Would definitely stay again!"
United States
Nicola
The price is RM497
RM601 total
includes taxes & fees
3 Jan - 4 Jan 2026
TONALA by Mr. W
Minibar, in-room safe, laptop workspace, blackout curtains
ONTO Alvaro Obregon Mexico City

ONTO Alvaro Obregon Mexico City

ONTO Alvaro Obregon Mexico City
4.0 star property
Roma Norte, 1.2 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (83)
"Beautiful terrace room. The staff was so incredibly friendly. It was close to everything so extremely walkable, would book again. "
United States
Annie
ONTO Alvaro Obregon Mexico City
Free WiFi
Casa Tenue

Casa Tenue

Casa Tenue
3.0 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (10)
"Cutest place, excellent location and phenomenal service! "
United States
Nehal
The price is RM1,097
RM1,310 total
includes taxes & fees
5 Jan - 6 Jan 2026
Casa Tenue
Restaurant
Nima Local House Hotel & Spa

Nima Local House Hotel & Spa

Nima Local House Hotel & Spa
4.0 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (93)
"Wonderful hotel with very nice and attentive stage in great location."
United States
Robert
The price is RM2,662
RM3,181 total
includes taxes & fees
13 Jan - 14 Jan 2026
Nima Local House Hotel & Spa
Exterior
Roso Guest House

Roso Guest House

Roso Guest House
4.0 star property
Roma Norte, 1.3 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (52)
"Room exceeded our expectations, breakfast was amazing, crew was very kind. "
United States
DAVID
The price is RM1,247
RM1,490 total
includes taxes & fees
7 Jan - 8 Jan 2026
Roso Guest House
Reception
Hotel Marbella

Hotel Marbella

Hotel Marbella
3.5 star property
Roma Norte, 0.7 km from National Medical Center (Siglo XXI)
9.0 out of 10, Wonderful, (1003)
"Good place to stay"
United States
Claudia
The price is RM422
RM505 total
includes taxes & fees
26 Jan - 27 Jan 2026
Hotel Marbella
Terrace/patio
Casa Oliva

Casa Oliva

Casa Oliva
3.0 star property
Roma Norte, 1.7 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (81)
"Loved the decor, cleanliness and helpful staff. "
United States
Stephanie
The price is RM947
RM1,131 total
includes taxes & fees
1 Jan - 2 Jan 2026
Casa Oliva
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top National Medical Center Hotel Reviews

Fiesta Americana Reforma

Fiesta Americana Reforma

10/10 Excellent
"A wonderful stay, this is a safe hotel, clean and with the best room service, ever. "
cesar 1-night trip
Posted 3 days ago
Fiesta Americana Reforma

Hotels near other National Medical Center attractions

Abelardo L. Rodriguez Murals

Enjoy an outing to Abelardo L. Rodriguez Murals during your stay in Mexico City. Experience the fascinating museums and great live music in this vibrant area.
See properties

Parque Delta

During your visit to Mexico City, you can browse for the perfect souvenirs at Parque Delta. Experience the fascinating museums and acclaimed art galleries in this vibrant area.
See properties

Frequently asked questions

What's the area like around National Medical Center (Siglo XXI)?
National Medical Center (Siglo XXI) is located in a historic area of Mexico City known for its top museums and popular art scene. If you're looking for a convenient place to stay, take a look at the 657 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to National Medical Center (Siglo XXI)?
Hotel Benidorm Mexico City is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free valet parking. It's located just a short 0.4 mi (0.7 km) from National Medical Center (Siglo XXI). Other good choices close by include Hotel Escala Colonia Roma and ULIV Roma Norte.
How many hotels will I be able to find close to National Medical Center (Siglo XXI)?
Expedia has 657 hotels and other accommodation options within a mile from National Medical Center (Siglo XXI).
If I need to cancel the hotel reservation for my stay near National Medical Center (Siglo XXI), will I receive a refund?
Yes, most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best deals near National Medical Center (Siglo XXI).
What can I see and do near National Medical Center (Siglo XXI)?
Chapultepec Castle, Templo Mayor Museum and Frida Kahlo Museum feature a variety of fascinating exhibits to see while you're in town. Paseo de la Reforma, Cibeles Fountain and Madero Street are some of the local landmarks to explore. You can watch performances at Blackberry Auditorium, Teatro Metropólitan and Insurgentes Theater if you're interested in local theatre.
How can I get to National Medical Center (Siglo XXI)?
With so many choices for transport, seeing the area around National Medical Center (Siglo XXI) is a breeze. You can access metro transport at Revolution Station, Metrobús Revolución Station and Buenavista Metro Station. To see more of the larger area, ride aboard one of the trains from Mexico City Buenavista Station.