𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Mesilla from RM208 (2026) - Fully Refundable Options

A wooden cart with large wheels in a desert landscape with ancient, earthen structures in the background.

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Our top choices for Mesilla hotels

A lobby with a stone fireplace, sofas, and a glass coffee table.

A spacious indoor dining area with high ceilings, large windows, and a variety of seating options including tables and booths.

A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.

A courtyard with outdoor seating, a small tree, and a stone wall.

1. Drury Inn & Suites Las Cruces

Las Cruces

shawn

RM379

RM439 total

includes taxes & fees

13 Sept - 14 Sept

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A golf course with a mountain range in the background.

A covered outdoor area with a patio, seating, and a small lawn.

2. Comfort Inn & Suites Las Cruces Mesilla

Las Cruces

Omar

RM373

RM433 total

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.

An indoor swimming pool with clear water, tiled edges, and a metal safety railing.

A gym with treadmills, elliptical machines, and exercise bikes.

A lobby with teal armchairs, a coffee bar, and a dining area.

3. Hampton Inn & Suites Las Cruces I-10

Las Cruces

Hector

RM476

RM550 total

includes taxes & fees

8 Sept - 9 Sept

A hotel room with two beds, a desk with a TV, a chair, and two lamps.

A kitchen with a wooden counter, coffee machines, a microwave, and various appliances.

A multi-story hotel with a central entrance, balconies, and a parking area.

4. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Las Cruces

Kyle

RM228

RM269 total

includes taxes & fees

13 Sept - 14 Sept

An outdoor patio area with seating arrangements, including sofas and chairs, under a covered structure with a wooden ceiling.

A Courtyard by Marriott hotel with a modern facade, multiple windows, and a covered entrance area.

A modern bar area with a long counter, bar stools, and a variety of liquor bottles.

A modern coffee shop interior with a wooden counter, seating area, and menu boards.

5. Courtyard by Marriott Las Cruces at NMSU

Las Cruces

Linda

RM540

RM622 total

includes taxes & fees

7 Sept - 8 Sept

A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.

A small, modern kitchenette with a white countertop, a sink, and a compact refrigerator.

A pool area with lounge chairs and umbrellas, surrounded by a fence and a building with multiple windows and balconies.

A modern hotel with a flat roof, large windows, and a well-lit entrance.

6. Springhill Suites By Marriott Las Cruces

Las Cruces

Verona R.

RM449

RM520 total

includes taxes & fees

9 Sept - 10 Sept

A buffet area with a variety of baked goods, a coffee station, and a decorative plant.

A cozy living room with a wooden sofa and armchair, a wooden coffee table, and a patterned rug.

A hotel room with two beds, wooden benches, a desk, and a chair.

A patio with a table and chairs, a large tree, a fountain, and a pool in the background.

7. Best Western Mission Inn

Las Cruces

Berlinda

RM290

RM339 total

includes taxes & fees

13 Sept - 14 Sept

A Days Inn with a large sign, a flag, and a well-maintained entrance area.

A hotel room with a bed, desk, chair, and a painting on the wall.

A hotel lobby with a reception desk, seating area, and a kitchenette.

A breakfast bar with coffee machines, a fruit bowl, and stacked paper cups.

8. Days Inn by Wyndham Las Cruces

Las Cruces

Naveen

RM195

RM231 total

includes taxes & fees

13 Sept - 14 Sept

A Holiday Inn Express & Suites with a covered entrance, a parking lot with several cars, and a clear sky.

A swimming pool with clear water, surrounded by walls with a mural, and multiple exits.

A hotel reception area with a marble floor, a reception desk, and a glass door entrance.

A gym with various exercise equipment, a bench, and a window with curtains.

9. Holiday Inn Express Hotel and Suites Las Cruces by IHG

Las Cruces

Jose

RM419

RM484 total

includes taxes & fees

11 Sept - 12 Sept

A spacious indoor courtyard with tiled flooring, wooden furniture, and a balcony with a railing.

A dining area with a table and chairs, a remote control on a rug, and a door leading to another room.

A lobby with a tiled floor, a staircase, and a patterned wall hanging.

An indoor swimming pool with tiled flooring, a metal pool ladder, and a few lounge chairs.

10. Ramada Hotel & Conference Center by Wyndham Las Cruces

Las Cruces

Jacob

RM319

RM371 total

includes taxes & fees

7 Sept - 8 Sept

A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.

A hotel room with a large bed, a desk, a chair, a flat-screen TV, and a window with curtains.

A modern hotel room with a blue sofa, armchairs, a flat-screen TV, and framed pictures on the wall.

An indoor swimming pool with clear water, a diving board, and lounge chairs.

11. Comfort Suites University Las Cruces

Las Cruces

Thomas

RM335

RM389 total

includes taxes & fees

27 Sept - 28 Sept

A pool area with a hot tub, lounge chairs, and a lifeguard stand.

A hotel room with a blue accent wall, a sofa, a bed, a desk, and a mirror.

A modern lobby with a sofa set, a small table with a potted plant, and a patterned wall.

A spacious living area with a fireplace, a television mounted above it, and a seating arrangement including a sofa and chairs.

12. Comfort Suites Las Cruces I-25 North

Las Cruces

Lalo

RM416

RM497 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor seating area with a fire pit, sofas, and chairs.

A modern hotel room with a wooden desk, a grey sofa, a small ottoman, a television, and a bed with a white headboard.

A modern cafe with an 'inspired table' sign, a 'good morning' greeting, and a variety of seating options including tables and chairs.

A modern hotel room with a large bed, a desk with a computer, a television, and a kitchenette.

13. Home2 Suites by Hilton Las Cruces

Las Cruces

Annette

RM498

RM575 total

includes taxes & fees

10 Sept - 11 Sept

A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.

A hotel with a distinctive arched entrance and a clear sign reading "Hilton Garden Inn."

A spacious living room with a fireplace, leather sofas, a wooden coffee table with fruit, and patterned rugs.

An outdoor patio with a built-in fireplace, surrounded by yellow cushioned chairs and a pergola overhead.

14. Hilton Garden Inn Las Cruces

Las Cruces

Kyle

RM442

RM511 total

includes taxes & fees

13 Sept - 14 Sept

A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.

A hotel room with a sofa, a dining table, a kitchen area with a microwave, refrigerator, and sink.

A spacious living area with a fireplace, comfortable seating, and a television.

A swimming pool with lounge chairs and a sunshade.

15. Hampton Inn & Suites Las Cruces I-25

Las Cruces

Deanna

RM426

RM493 total

includes taxes & fees

8 Sept - 9 Sept

A pool area with a fountain, palm trees, and outdoor seating.

A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.

A spacious atrium with a central fountain, large potted plants, and a high ceiling with skylights.

A hallway with a tiled floor, a chandelier, potted plants, and a cross at the end.

16. Hotel Encanto de Las Cruces

Las Cruces

Cassandra

RM378

RM548 total

includes taxes & fees

16 Sept - 17 Sept

A hotel with a pool area, stone walls, and a palm tree.

A hotel room with a large bed, a desk, a dresser, a vanity with a mirror, and a painting on the wall.

A hotel with a central courtyard, multiple balconies, and a stone wall.

A reception desk with a wooden finish and decorative diamond patterns, a wall-mounted sign reading "Quality by Choice Hotels," and a framed picture on the wall.

17. Quality Inn & Suites Las Cruces - University Area

Las Cruces

frances

RM215

RM254 total

includes taxes & fees

18 Sept - 19 Sept

A hotel lobby with a 'Connect & Print' service area, a fireplace, and a seating area with blue chairs.

A lobby with a stone wall, a fireplace, and blue chairs.

A reception desk with a wooden finish, a sign reading "Corner Market," and a display of snacks.

A hallway with two refrigerated beverage dispensers stocked with various drinks and snacks.

18. Fairfield Inn by Marriott Las Cruces

Las Cruces

Lola

RM560

RM659 total

includes taxes & fees

18 Sept - 19 Sept

A reception area with two reception desks, a blue geometric wall design, and a sign for 'Holiday Inn Express & Suites'.

A modern hotel lobby with a wooden ceiling, a seating area with a sofa and chairs, a small table with a computer, and a decorative wall with a map design.

A Holiday Inn Express & Suites hotel with a brick facade, multiple floors, and a covered entrance.

A swimming pool with clear water, surrounded by lounge chairs and a tiled deck.

19. Holiday Inn Express & Suites Las Cruces North by IHG

Las Cruces

Deanna

RM475

RM549 total

includes taxes & fees

8 Sept - 9 Sept

A compact kitchen with a microwave, coffee maker, and a small trash bin. A dining table and chairs are visible in the foreground.

A parking lot with several cars, a building with a blue sign, and mountains in the background.

A building with multiple rooms, each with a door and windows, and a small outdoor seating area with tables and benches.

A hotel room with two beds, a desk, a chair, and a window with curtains.

20. Motel 9 Las Cruces

Las Cruces

GUSTAVO Alejandro

RM217

RM257 total

includes taxes & fees

4 Sept - 5 Sept

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Stay near popular Mesilla attractions

Mesillia Plaza

9.2/10 (5 reviews)

This National Historic Landmark features preserved 19th-century adobe architecture from the Gadsden Purchase era. Browse unique shops, savour authentic cuisine, and experience cultural events in this historic square.

See properties

Fountain Theatre

9.2/10 (19 reviews)

New Mexico's oldest cinema, the Fountain Theatre has showcased independent films since 1905 in a historic adobe building. Enjoy art-house cinema with refreshments while admiring original desert murals.

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Fountain Theater

8.6/10 (14 reviews)

The Fountain Theatre, New Mexico's oldest continuously operating film house, showcases independent and foreign films in a historic 1905 setting. Enjoy fresh popcorn in this intimate cultural landmark.

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San Albino Basilica

This historic Spanish Colonial basilica in Mesilla features intricate stained glass windows and serene ambiance. Attend a morning Mass to experience the community's spiritual heart.

See properties

Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

See all hotels in Mesilla

A rustic building with a wooden door, a hanging red chili, and a cactus plant.

Top Mesilla Hotel Reviews

Drury Inn & Suites Las Cruces

8/10 Good

"My only suggestion to others is to request a room on the side of the hotel that does NOT face I-10 or else you get to listen to traffic on highway until early morning hours. Other than that, stay was nice. Plenty of restaurants nearby and a Super Walmart just 5 mins down the road. Evening snacks & drinks were nice and breakfast was pretty good too."

Days Inn by Wyndham Las Cruces

10/10 Excellent

"This was a good location and quick access to Mesilla and NMSU campus. Has basic amenities and works well if you’re low maintenance. Would stay again."

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

10/10 Excellent

"The room was very clean and found easy parking everyday. The air conditioning in the room was nice and quiet. The young girl at the desk was so nice and helpful. We like that everything we needed was close by like Walmart and plenty of places to eat.. When in Las Cruces we will definitely rebook with them."

Best Western Mission Inn

10/10 Excellent

"Clean room, quite, nice play for the night"

Holiday Inn Express & Suites Las Cruces North by IHG

10/10 Excellent

"Lean rooms, staff were very nice, breakfast offered choices."

Hilton Garden Inn Las Cruces

8/10 Good

"We had a good stay, would have been perfect if they would have cleaned our room after our first night."

Quality Inn & Suites Las Cruces - University Area

8/10 Good

"Rooms were clean, staff was great and Restaurants close by"

Courtyard by Marriott Las Cruces at NMSU

10/10 Excellent

"Bar and restaurant was very convenient. The staff was helpful. The hotel was clean and it was right off of the hwy 10 convenient for our trip back to Phoenix. The air conditioner in our room worked perfect. It was spacious coffee maker was a Keurig, which is a plus for us since we bring our own favorite coffee. They also serve Starbucks coffee in the café. In case you’re interested, the EV is ChargePoint. The other hotels we stayed at had free EV chargers."

More cheap stays in Mesilla

Days Inn by Wyndham Las Cruces

755 Avenida De Mesilla Las Cruces NM

RM195

RM231 total

13 Sept - 14 Sept

includes taxes & fees

8.2/10 Very good! (1,612 reviews)

Sleep Inn University

2121 S Triviz Dr Las Cruces NM

RM241

RM283 total

27 Sept - 28 Sept

includes taxes & fees

7.6/10 Good! (1,002 reviews)

Best Western Mission Inn

1765 S Main St Las Cruces NM

RM290

RM339 total

13 Sept - 14 Sept

includes taxes & fees

8.8/10 Excellent! (1,251 reviews)

Comfort Suites University Las Cruces

2101 S Triviz Drive Las Cruces NM

RM335

RM389 total

27 Sept - 28 Sept

includes taxes & fees

Comfort Suites Las Cruces I-25 North

236 N Telshor Blvd. Las Cruces NM

RM416

RM497 total

27 Sept - 28 Sept

includes taxes & fees

Holiday Inn Express & Suites Las Cruces North by IHG

2142 Telshor Ct Las Cruces NM

RM475

RM549 total

8 Sept - 9 Sept

includes taxes & fees

9/10 Wonderful! (1,001 reviews)

Frequently asked questions

What's the best place for a stay in Mesilla?

Located 4.5 mi (7.3 km) from the heart of Mesilla, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces. See all available top hotels, or vacation rentals in Mesilla.

If I need to cancel my hotel reservation in Mesilla, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesilla.

What are some hotels with pools in Mesilla?

Hotel Encanto de Las Cruces: Features 3 bars, an outdoor pool and a 24-hour fitness centre. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces are two additional hotels that offer an on-site pool. View all hotels with pools in Mesilla.

What is staying in Mesilla like?

Visitors can enjoy all that Mesilla has to offer, including the restaurants, shopping and theatres. In Mesilla, there are 12 hotels and other accommodation options to choose from. Find out more about Mesilla.

What should I do while I'm visiting Mesilla?

Cultural venues include Fountain Theatre and Fountain Theater. Landmarks like Mesillia Plaza and San Albino Basilica might be worth a visit. Additionally, you might want to add Rio Grande to your itinerary. Take a look at what more there is to see and do in Expedia's Mesilla guide.

What's the seasonal weather in Mesilla?

The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Mesilla is 227 mm.

Mesilla hotels from RM208

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Mesilla

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mesilla hotels

1. Drury Inn & Suites Las Cruces

2. Comfort Inn & Suites Las Cruces Mesilla

3. Hampton Inn & Suites Las Cruces I-10

4. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

5. Courtyard by Marriott Las Cruces at NMSU

6. Springhill Suites By Marriott Las Cruces

7. Best Western Mission Inn

8. Days Inn by Wyndham Las Cruces

9. Holiday Inn Express Hotel and Suites Las Cruces by IHG

10. Ramada Hotel & Conference Center by Wyndham Las Cruces

11. Comfort Suites University Las Cruces

12. Comfort Suites Las Cruces I-25 North

13. Home2 Suites by Hilton Las Cruces

14. Hilton Garden Inn Las Cruces

15. Hampton Inn & Suites Las Cruces I-25

16. Hotel Encanto de Las Cruces

17. Quality Inn & Suites Las Cruces - University Area

18. Fairfield Inn by Marriott Las Cruces

19. Holiday Inn Express & Suites Las Cruces North by IHG

20. Motel 9 Las Cruces

Stay near popular Mesilla attractions

Mesillia Plaza

Fountain Theatre

Fountain Theater

San Albino Basilica

Learn more about Mesilla

Top Mesilla Hotel Reviews

Drury Inn & Suites Las Cruces

Days Inn by Wyndham Las Cruces

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Best Western Mission Inn

Holiday Inn Express & Suites Las Cruces North by IHG

Hilton Garden Inn Las Cruces

Quality Inn & Suites Las Cruces - University Area

Courtyard by Marriott Las Cruces at NMSU

More cheap stays in Mesilla

Days Inn by Wyndham Las Cruces

Sleep Inn University

Best Western Mission Inn

Comfort Suites University Las Cruces

Comfort Suites Las Cruces I-25 North

Holiday Inn Express & Suites Las Cruces North by IHG

Frequently asked questions

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