𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Mesilla from RM231 (2026) - Fully Refundable Options

A wooden cart with large wheels in a desert landscape with ancient, earthen structures in the background.

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Our top choices for Mesilla hotels

A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.

An indoor swimming pool with clear water, tiled edges, and a metal safety railing.

A gym with treadmills, elliptical machines, and exercise bikes.

A lobby with teal armchairs, a coffee bar, and a dining area.

1. Hampton Inn & Suites Las Cruces I-10

Las Cruces

Brandon

RM482

RM557 total

includes taxes & fees

24 Oct - 25 Oct

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A golf course with a mountain range in the background.

A hotel dining area with multiple tables and chairs, a coffee station, and a reception desk.

A covered outdoor area with a patio, seating, and a small lawn.

2. Comfort Inn & Suites Las Cruces Mesilla

Las Cruces

Carlos

RM399

RM463 total

includes taxes & fees

15 Nov - 16 Nov

A lobby with a stone fireplace, sofas, and a glass coffee table.

A courtyard with outdoor seating, a small tree, and a stone wall.

A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.

A spacious indoor dining area with high ceilings, large windows, and a variety of seating options including tables and booths.

3. Drury Inn & Suites Las Cruces

Las Cruces

Jessica

RM433

RM501 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.

A pool area with lounge chairs and umbrellas, surrounded by a fence and a building with multiple windows and balconies.

A small, modern kitchenette with a white countertop, a sink, and a compact refrigerator.

A compact kitchenette with a microwave, a small sink, and a refrigerator.

4. Springhill Suites By Marriott Las Cruces

Las Cruces

Miriam

RM437

RM506 total

includes taxes & fees

16 Nov - 17 Nov

A hotel room with two beds, a desk with a TV, a chair, and two lamps.

A multi-story hotel with a central entrance, balconies, and a parking area.

A kitchen with a wooden counter, coffee machines, a microwave, and various appliances.

5. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Las Cruces

Kathy

RM239

RM281 total

includes taxes & fees

8 Nov - 9 Nov

A spacious indoor courtyard with tiled flooring, wooden furniture, and a balcony with a railing.

An indoor swimming pool with tiled flooring, a metal pool ladder, and a few lounge chairs.

A hotel room with a large bed, a television, a desk, and a chair.

A lobby with a tiled floor, a staircase, and a patterned wall hanging.

6. Ramada Hotel & Conference Center by Wyndham Las Cruces

Las Cruces

Luis

RM323

RM376 total

includes taxes & fees

5 Nov - 6 Nov

A hotel room with a bathtub, a sofa, a bed, a desk, and a television.

A conference room with multiple tables, chairs, and a carpeted floor.

A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.

A hotel room with a sofa, a small table, a desk, a chair, a lamp, a coffee maker, and a refrigerator.

7. Holiday Inn Express Hotel and Suites Las Cruces by IHG

Las Cruces

Karie

RM388

RM449 total

includes taxes & fees

16 Nov - 17 Nov

An outdoor patio area with seating arrangements, including sofas and chairs, under a covered structure with a wooden ceiling.

A modern hotel lobby with a large sofa, armchairs, a coffee table, and a TV.

A modern coffee shop interior with a wooden counter, seating area, and menu boards.

A Courtyard by Marriott hotel with a modern facade, multiple windows, and a covered entrance area.

8. Courtyard by Marriott Las Cruces at NMSU

Las Cruces

Linda

RM621

RM714 total

includes taxes & fees

30 Oct - 31 Oct

A buffet area with a variety of baked goods, a coffee station, and a decorative plant.

A cozy living room with a wooden sofa and armchair, a wooden coffee table, and a patterned rug.

A patio with a table and chairs, a large tree, a fountain, and a pool in the background.

9. Best Western Mission Inn

Las Cruces

Steven

RM327

RM381 total

includes taxes & fees

20 Oct - 21 Oct

A Days Inn with a large sign, a flag, and a well-maintained entrance area.

A hotel lobby with a reception desk, seating area, and a kitchenette.

An outdoor patio with wooden benches and a grill area.

A hotel room with a bed, desk, chair, and a painting on the wall.

10. Days Inn by Wyndham Las Cruces

Las Cruces

Donald

RM198

RM234 total

includes taxes & fees

5 Nov - 6 Nov

A hotel with a pool area, stone walls, and a palm tree.

A hotel room with a large bed, a desk, a dresser, a vanity with a mirror, and a painting on the wall.

A hotel with a central courtyard, multiple balconies, and a stone wall.

A hotel kitchen area with a coffee station, a refrigerator, and a sign indicating a fresh juice bar.

11. Quality Inn & Suites Las Cruces - University Area

Las Cruces

Sue

RM219

RM259 total

includes taxes & fees

15 Nov - 16 Nov

A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.

An indoor swimming pool with clear water, a diving board, and lounge chairs.

A hotel room with a bed, a sofa, a desk, and a TV. There are framed pictures on the wall.

A modern hotel room with a blue sofa, armchairs, a flat-screen TV, and framed pictures on the wall.

12. Comfort Suites University Las Cruces

Las Cruces

Becky Ann

RM340

RM395 total

includes taxes & fees

10 Nov - 11 Nov

A pool area with a fountain, palm trees, and outdoor seating.

A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.

A lobby with a patterned floor, a central table, chairs, a statue, and a large floral arrangement.

A fountain with a lotus design in a pool, surrounded by a balustrade and palm trees.

13. Hotel Encanto de Las Cruces

Las Cruces

ronald

RM436

RM615 total

includes taxes & fees

1 Nov - 2 Nov

A pool area with a hot tub, lounge chairs, and a lifeguard stand.

A modern lobby with a sofa set, a small table with a potted plant, and a patterned wall.

A hotel room with a blue accent wall, a sofa, a bed, a desk, and a mirror.

A hotel with a modern design, featuring a covered entrance and multiple floors.

14. Comfort Suites Las Cruces I-25 North

Las Cruces

Jessica

RM421

RM503 total

includes taxes & fees

15 Nov - 16 Nov

A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.

A breakfast buffet with various food items, including fruits, pastries, and hot beverages.

A spacious living room with a fireplace, leather sofas, a wooden coffee table with fruit, and patterned rugs.

An outdoor patio with a built-in fireplace, surrounded by yellow cushioned chairs and a pergola overhead.

15. Hilton Garden Inn Las Cruces

Las Cruces

David

RM451

RM522 total

includes taxes & fees

31 Oct - 1 Nov

A modern hotel room with a bed, a sofa, a desk, and a television.

A modern lounge area with a sofa, chairs, and tables, featuring pendant lighting and large windows.

An outdoor seating area with a fire pit, sofas, and chairs.

A modern hotel room with a large bed, a desk with a computer, a television, and a kitchenette.

16. Home2 Suites by Hilton Las Cruces

Las Cruces

Annette

RM576

RM663 total

includes taxes & fees

30 Oct - 31 Oct

A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.

A hotel room with a sofa, a dining table, a kitchen area with a microwave, refrigerator, and sink.

A swimming pool with lounge chairs and a sunshade.

17. Hampton Inn & Suites Las Cruces I-25

Las Cruces

Peter

RM465

RM538 total

includes taxes & fees

8 Nov - 9 Nov

Two adjacent beds with white bedding, a bedside table with a lamp, and a painting on the wall.

A spacious lobby with a tiled floor, a reception desk, and a staircase leading to upper floors.

A swimming pool with lounge chairs and a building with a red-tiled roof in the background.

A hotel with a signboard, arched windows, and a clear sky.

18. Go2 By Relianse

Las Cruces

RM253

RM310 total

includes taxes & fees

18 Oct - 19 Oct

A modern breakfast bar with a coffee machine, cereal and fruit options, and a yogurt, eggs, and milk dispenser.

A large, modern building with a curved roof and large glass windows, likely a hotel or conference center.

A hotel room with a blue sofa, a wooden coffee table, two beds with white bedding, a headboard with a blue accent, a framed picture on the wall, and a window with a geometric blind.

A modern hotel lobby with a wooden ceiling, a seating area with a sofa and chairs, a small table with a computer, and a decorative wall with a map design.

19. Holiday Inn Express & Suites Las Cruces North by IHG

Las Cruces

Deanna

RM518

RM598 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a desk, a television, and a window with curtains.

A windmill and a building with a dome roof in a grassy area.

A church with two towers and a large tree in front.

A hotel with a sign reading "Super 8" and a stone facade.

20. Super 8 by Wyndham Las Cruces University Area

Las Cruces

Daniel

RM195

RM231 total

includes taxes & fees

2 Nov - 3 Nov

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Stay near popular Mesilla attractions

Mesillia Plaza

9.2/10 (5 reviews)

This National Historic Landmark features preserved 19th-century adobe architecture from the Gadsden Purchase era. Browse unique shops, savour authentic cuisine, and experience cultural events in this historic square.

See properties

Fountain Theatre

9.2/10 (19 reviews)

New Mexico's oldest cinema, the Fountain Theatre has showcased independent films since 1905 in a historic adobe building. Enjoy art-house cinema with refreshments while admiring original desert murals.

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Fountain Theater

8.6/10 (14 reviews)

The Fountain Theatre, New Mexico's oldest continuously operating film house, showcases independent and foreign films in a historic 1905 setting. Enjoy fresh popcorn in this intimate cultural landmark.

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San Albino Basilica

This historic Spanish Colonial basilica in Mesilla features intricate stained glass windows and serene ambiance. Attend a morning Mass to experience the community's spiritual heart.

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Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

See all hotels in Mesilla

A rustic building with a wooden door, a hanging red chili, and a cactus plant.

Top Mesilla Hotel Reviews

Days Inn by Wyndham Las Cruces

10/10 Excellent

"People at front desk always helpful and friendly"

Holiday Inn Express & Suites Las Cruces North by IHG

10/10 Excellent

"The entire hotel was very clean and well maintained. Very enjoyable stay!"

Comfort Inn & Suites Las Cruces Mesilla

10/10 Excellent

"Very clean and quiet, staff was nice"

Best Western Mission Inn

10/10 Excellent

"It is an older building, but I liked the faceted that it was very clean. I also enjoyed the breakfast and the staff was very helpful."

Hampton Inn & Suites Las Cruces I-25

8/10 Good

"All as expected"

Quality Inn & Suites Las Cruces - University Area

10/10 Excellent

"Well kept and offered anything I would need on a short trip. Nice location to Main Street."

Drury Inn & Suites Las Cruces

10/10 Excellent

"Great 1st time. Im sold"

Ramada Hotel & Conference Center by Wyndham Las Cruces

10/10 Excellent

"Staff was very helpful and delightful. I really enjoyed staying at this establishment."

Fairfield Inn by Marriott Las Cruces

10/10 Excellent

"Front desk staff was super! The hotel was very quiet especially during quiet hours which is never the case in most hotels. Loved staying there. Beds were very comfortable."

More cheap stays in Mesilla

Days Inn by Wyndham Las Cruces

755 Avenida De Mesilla Las Cruces NM

RM198

RM234 total

5 Nov - 6 Nov

includes taxes & fees

8.2/10 Very good! (1,645 reviews)

Motel 6 Las Cruces, NM - Telshor

2120 Summit Ct Las Cruces NM

RM227

RM267 total

18 Oct - 19 Oct

includes taxes & fees

7.2/10 Good! (1,002 reviews)

Sleep Inn University

2121 S Triviz Dr Las Cruces NM

RM239

RM281 total

8 Nov - 9 Nov

includes taxes & fees

Best Western Mission Inn

1765 S Main St Las Cruces NM

RM327

RM381 total

20 Oct - 21 Oct

includes taxes & fees

8.8/10 Excellent! (1,239 reviews)

Comfort Suites University Las Cruces

2101 S Triviz Drive Las Cruces NM

RM340

RM395 total

10 Nov - 11 Nov

includes taxes & fees

8/10 Very good! (1,000 reviews)

Comfort Suites Las Cruces I-25 North

236 N Telshor Blvd. Las Cruces NM

RM421

RM503 total

15 Nov - 16 Nov

includes taxes & fees

9.2/10 Wonderful! (1,003 reviews)

Frequently asked questions

What's the best place for a stay in Mesilla?

Located 0.1 mi (0.2 km) from the heart of Mesilla, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are Ramada Hotel & Conference Center by Wyndham Las Cruces and La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain. See all available top hotels, or vacation rentals in Mesilla.

If I need to cancel my hotel reservation in Mesilla, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesilla.

What are some hotels with pools in Mesilla?

Hotel Encanto de Las Cruces: Hotel located near New Mexico State University. Features 3 bars, an outdoor pool and a 24-hour fitness centre. Ramada Hotel & Conference Center by Wyndham Las Cruces and La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain are two additional hotels that offer an on-site pool. View all hotels with pools in Mesilla.

What is staying in Mesilla like?

Visitors can enjoy all that Mesilla has to offer, including the restaurants, shopping and theatres. In Mesilla, there are 12 hotels and other accommodation options to choose from. Find out more about Mesilla.

What should I do while I'm visiting Mesilla?

Cultural venues include Fountain Theatre and Fountain Theater. Landmarks like Mesillia Plaza and San Albino Basilica might be worth a visit. Additionally, you might want to add Rio Grande to your itinerary. Take a look at what more there is to see and do in Expedia's Mesilla guide.

What's the seasonal weather in Mesilla?

The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Mesilla is 227 mm.

Mesilla hotels from RM231

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Mesilla

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mesilla hotels

1. Hampton Inn & Suites Las Cruces I-10

2. Comfort Inn & Suites Las Cruces Mesilla

3. Drury Inn & Suites Las Cruces

4. Springhill Suites By Marriott Las Cruces

5. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

6. Ramada Hotel & Conference Center by Wyndham Las Cruces

7. Holiday Inn Express Hotel and Suites Las Cruces by IHG

8. Courtyard by Marriott Las Cruces at NMSU

9. Best Western Mission Inn

10. Days Inn by Wyndham Las Cruces

11. Quality Inn & Suites Las Cruces - University Area

12. Comfort Suites University Las Cruces

13. Hotel Encanto de Las Cruces

14. Comfort Suites Las Cruces I-25 North

15. Hilton Garden Inn Las Cruces

16. Home2 Suites by Hilton Las Cruces

17. Hampton Inn & Suites Las Cruces I-25

18. Go2 By Relianse

19. Holiday Inn Express & Suites Las Cruces North by IHG

20. Super 8 by Wyndham Las Cruces University Area

Stay near popular Mesilla attractions

Mesillia Plaza

Fountain Theatre

Fountain Theater

San Albino Basilica

Learn more about Mesilla

Top Mesilla Hotel Reviews

Days Inn by Wyndham Las Cruces

Holiday Inn Express & Suites Las Cruces North by IHG

Comfort Inn & Suites Las Cruces Mesilla

Best Western Mission Inn

Hampton Inn & Suites Las Cruces I-25

Quality Inn & Suites Las Cruces - University Area

Drury Inn & Suites Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces

Fairfield Inn by Marriott Las Cruces

More cheap stays in Mesilla

Days Inn by Wyndham Las Cruces

Motel 6 Las Cruces, NM - Telshor

Sleep Inn University

Best Western Mission Inn

Comfort Suites University Las Cruces

Comfort Suites Las Cruces I-25 North

Frequently asked questions

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