Hotels near Mayo Clinic Florida

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Check prices for these dates

Tonight
27 Mar - 28 Mar
Tomorrow
28 Mar - 29 Mar
This weekend
27 Mar - 29 Mar
Next weekend
3 Apr - 5 Apr

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Our top choices for Mayo Clinic Florida hotels

Lobby lounge

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (475 reviews)
"Great stay! Clean room, friendly staff. "
United States
Sabrena
The price is RM651
RM739 total
includes taxes & fees
3 Apr - 4 Apr
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Breakfast, lunch, dinner served; American cuisine

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (185 reviews)
"Great place to stay"
United States
Judy
The price is RM707
RM803 total
includes taxes & fees
3 Apr - 4 Apr
Hilton Jacksonville At Mayo Clinic
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (595 reviews)
"Very nice accommodation , clean , and comfortable"
United States
Kevin
The price is RM483
RM549 total
includes taxes & fees
27 Apr - 28 Apr
TownePlace Suites by Marriott Jacksonville East
Lobby

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,001 reviews)
"Nice room nice stay friendly staff"
United States
Thomas
The price is RM439
RM498 total
includes taxes & fees
19 Apr - 20 Apr
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,011 reviews)
"Great stay!"
United States
Satavia
The price is RM411
RM467 total
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (767 reviews)
"Room very clear; staff friendly and helpful; safe parking with accessibility to Mayo Clinic "
United States
Nancy
The price is RM643
RM730 total
includes taxes & fees
3 Apr - 4 Apr
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Property amenity

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (543 reviews)
"Rooms were clean. Proximity to beach was optimal. Daily made to order breakfast was simply amazing. "
United States
Sean M
The price is RM643
RM730 total
includes taxes & fees
19 Apr - 20 Apr
Element Jacksonville Beach
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,002 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is RM523
RM594 total
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
BBQ/picnic Area

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (456 reviews)
"The room was clean, staff was friendly and helpful, and location was great. "
United States
Rocky
The price is RM721
RM819 total
includes taxes & fees
30 Mar - 31 Mar
The Hotel Palms Poolside
Down duvets, minibar, iron/ironing board, WiFi

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is RM759
RM862 total
includes taxes & fees
31 Mar - 1 Apr
The Hotel Palms Courtyard
Property amenity

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (93 reviews)
"Loved the staff, the cleanliness, and the food was excellent. Really enjoyed my stay here!!"
United States
Toni
The price is RM499
RM567 total
includes taxes & fees
19 Apr - 20 Apr
TownePlace Suites by Marriott® Jacksonville Mayport
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,054 reviews)
"Great staff and Clean hotel "
United States
Tyniesha
The price is RM521
RM591 total
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Lounge

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (184 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is RM675
RM766 total
includes taxes & fees
29 Mar - 30 Mar
AC Hotel Jacksonville St Johns Town Center
Couples treatment room(s), sauna, hot tub, steam room, body treatments

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (818 reviews)
"Wonderful place to visit to relax. Very clean, very friendly and courteous staff. Great view from the balcony."
United States
Greg
The price is RM2,375
RM2,763 total
includes taxes & fees
16 Apr - 17 Apr
Ponte Vedra Inn & Club
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,787 reviews)
"beautiful hotel, good location"
United States
Robert E.
The price is RM679
RM771 total
includes taxes & fees
5 Apr - 6 Apr
Margaritaville Jacksonville Beach
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"Great place to stay at!"
United States
R.
The price is RM535
RM607 total
includes taxes & fees
5 Apr - 6 Apr
Hyatt Place Jacksonville / St. Johns Town Center
Lobby

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,008 reviews)
"Great stay all around "
United States
Jeffrey
The price is RM694
RM774 total
includes taxes & fees
5 Apr - 6 Apr
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,003 reviews)
"Great hotel, very friendly, free breakfast! "
United States
Daniel
The price is RM487
RM553 total
includes taxes & fees
19 Apr - 20 Apr
Holiday Inn Express Jacksonville Beach by IHG
Snack bar

Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
Southside, 8.7 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (875 reviews)
"Clean room, professional staff, & good breakfast bar"
United States
Dwight
The price is RM485
RM551 total
includes taxes & fees
26 Apr - 27 Apr
Tru By Hilton Jacksonville St Johns Town Center
Property amenity

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Deerwood, 9.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,003 reviews)
"Nice stay, soft beds"
United States
Charles
The price is RM540
RM613 total
includes taxes & fees
3 Apr - 4 Apr
Sheraton Jacksonville Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby lounge
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
475 reviews
View
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
185 reviews
View
Terrace/patio
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
595 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,001 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
8.8
Excellent
1,011 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Best Western Oceanfront

Best Western Oceanfront

2/10 Terrible
"Not sufficient parking for guests. Was called a thief by staff for taking a water bottle of water at breakfast from the cooler."
Andrew 1-night trip
Posted 2 hours ago
Best Western Oceanfront

Hotels near other Mayo Clinic Florida attractions

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Windsor Commons Shopping Center

You can find the perfect gifts to bring home at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's acclaimed theatre scene and great live music.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 49 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 49 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, SeaWalk Pavillion and Players by the Sea. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.