Hotels near Mayo Clinic Florida

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Our top choices for Mayo Clinic Florida hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (530 reviews)
"Great place to stay!"
United States
Chad
The price is RM646
RM734 total
includes taxes & fees
12 Jun - 13 Jun
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (246 reviews)
"Beautiful hotel!! It was extremely quiet and we all slept amazing!!"
United States
christine
The price is RM647
RM735 total
includes taxes & fees
26 Jun - 27 Jun
Hilton Jacksonville At Mayo Clinic

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (622 reviews)
"This is always a great place to stay especially because it’s close to the Mayo Clinic …a five minute drive"
United States
Miriam
The price is RM500
RM567 total
includes taxes & fees
14 Jun - 15 Jun
TownePlace Suites by Marriott Jacksonville East

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,013 reviews)
"Convenient location; clean and comfortable room; very friendly and helpful front desk staff"
United States
Tonya
The price is RM464
RM526 total
includes taxes & fees
14 Jun - 15 Jun
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (776 reviews)
"Enjoyed our stay"
United States
Alan
The price is RM608
RM690 total
includes taxes & fees
20 Jun - 21 Jun
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (558 reviews)
"Best hotel ever 😊"
United States
Tablo
The price is RM608
RM690 total
includes taxes & fees
7 Jun - 8 Jun
Element by Marriott Jacksonville Beach

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (479 reviews)
"Very clean and quiet, even with the festival in AB. Felt very safe. Loved the pool area!"
United States
Liza
The price is RM716
RM813 total
includes taxes & fees
7 Jun - 8 Jun
The Hotel Palms Poolside

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
Deerwood, 7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (63 reviews)
"Great location and awesome staff"
United States
Beth
The price is RM496
RM563 total
includes taxes & fees
7 Jun - 8 Jun
Hyatt Studios Jacksonville/St Johns Town Center

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,008 reviews)
"Great place to stay"
United States
Clyde
The price is RM496
RM563 total
includes taxes & fees
11 Jun - 12 Jun
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (302 reviews)
"Clean, room was very nice, staff was helpful"
United States
Angela
The price is RM754
RM855 total
includes taxes & fees
8 Jun - 9 Jun
The Hotel Palms Courtyard

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (822 reviews)
"Beautiful room looking at the ocean, staff super helpful, property immaculate."
United Kingdom
Michael
The price is RM1,978
RM2,321 total
includes taxes & fees
16 Jun - 17 Jun
Ponte Vedra Inn & Club

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,132 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is RM568
RM645 total
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (205 reviews)
"Great stay! Highly recommend and tons to do in the area."
United States
Adam
The price is RM710
RM806 total
includes taxes & fees
5 Jun - 6 Jun
AC Hotel Jacksonville St Johns Town Center

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (4,021 reviews)
"Very nice staff and beautiful property"
United States
Marley
The price is RM668
RM759 total
includes taxes & fees
7 Jun - 8 Jun
Margaritaville Jacksonville Beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,001 reviews)
"Great stay"
United States
Adam
The price is RM480
RM544 total
includes taxes & fees
7 Jun - 8 Jun
Best Western Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (711 reviews)
"Room was clean, lots to do and place to eat close by. Breakfast was good. Overall a good hotel."
United States
Yadiel
The price is RM758
RM860 total
includes taxes & fees
1 Jul - 2 Jul
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,004 reviews)
"Very nice property and staff"
United States
BONINA
The price is RM841
RM954 total
includes taxes & fees
15 Jun - 16 Jun
Four Points by Sheraton Jacksonville Beachfront

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,001 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is RM521
RM581 total
includes taxes & fees
2 Jul - 3 Jul
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"The hotel and the staff were amazing! My family had a wonderful time there, the rooms were clean and a good breakfast! Excellent location!"
United States
Maria
The price is RM468
RM531 total
includes taxes & fees
7 Jun - 8 Jun
Holiday Inn Express Jacksonville Beach by IHG

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,041 reviews)
"Great stay!"
United States
William
The price is RM504
RM572 total
includes taxes & fees
11 Jun - 12 Jun
Hyatt Place Jacksonville / St. Johns Town Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
530 reviews
View
Breakfast, lunch and dinner served
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
246 reviews
View
Terrace/patio
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
622 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
9.0
Wonderful
1,013 reviews
View
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4
Very good
776 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 45 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 45 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Wilson Center For the Arts and Players by the Sea. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.