Hotels in Matlacha Isles, Cape Coral

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
23 Oct - 24 Oct
Tomorrow
24 Oct - 25 Oct
This weekend
24 Oct - 26 Oct
Next weekend
31 Oct - 2 Nov

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in Matlacha Isles, Cape Coral

On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa
Marriott Sanibel Harbour Resort & Spa
4.0 star property
8.4 out of 10, Very good, (1003)
"It is a beautiful resort! It had everything, dining , pool, very relaxing. The staff and rooms were incredible."
United States
Christine
The price is RM680
RM864 total
includes taxes & fees
2 Nov - 3 Nov
Marriott Sanibel Harbour Resort & Spa
Property amenity
Comfort Suites Fort Myers East I-75
Comfort Suites Fort Myers East I-75
2.5 star property
9.6 out of 10, Exceptional, (308)
"Very clean and nice hotel. Great stay. "
United States
Ryan
The price is RM404
RM450 total
includes taxes & fees
26 Oct - 27 Oct
Comfort Suites Fort Myers East I-75
Interior entrance
Allure Suites
Allure Suites
3.0 star property
7.6 out of 10, Good, (1000)
"Was clean staff was very nice"
United States
Richard J
The price is RM301
RM335 total
includes taxes & fees
24 Oct - 25 Oct
Allure Suites
Lobby
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
7.8 out of 10, Good, (1458)
"Great location and very nice staff."
United States
Sara
The price is RM293
RM327 total
includes taxes & fees
28 Oct - 29 Oct
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Lobby
Best Western Fort Myers Inn & Suites
Best Western Fort Myers Inn & Suites
2.5 star property
8.8 out of 10, Excellent, (1046)
"Nice place and awesome breakfast"
United States
Even
The price is RM301
RM335 total
includes taxes & fees
26 Oct - 27 Oct
Best Western Fort Myers Inn & Suites
Hypo-allergenic bedding, down duvets, individually decorated
Econo Lodge Fort Myers North
Econo Lodge Fort Myers North
2.0 star property
5.6 out of 10, (295)
" This facility has a good mattress. I do not get up with back pain. The wall are very thick ; I do not hear anything that's going in the room next to me. I would 100% go back and stay there again. "
United States
Ronald
The price is RM244
RM272 total
includes taxes & fees
26 Oct - 27 Oct
Econo Lodge Fort Myers North
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel
Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.6 out of 10, Excellent, (1000)
"Nice place to stay and staff was friendly."
United States
Monique
The price is RM436
RM486 total
includes taxes & fees
28 Oct - 29 Oct
Residence Inn by Marriott Fort Myers Sanibel
Outdoor pool
Days Inn by Wyndham Fort Myers Springs Resort
Days Inn by Wyndham Fort Myers Springs Resort
2.5 star property
6.0 out of 10, (1001)
"It was a really clean hotel "
United States
Tina
The price is RM301
RM335 total
includes taxes & fees
28 Oct - 29 Oct
Days Inn by Wyndham Fort Myers Springs Resort
Exterior
Best Western Fort Myers Waterfront
Best Western Fort Myers Waterfront
3.0 star property
7.2 out of 10, Good, (1000)
"Staff is excellent and so is the view. Brianna does a great job with the free breakfast too"
United States
Salvatore
The price is RM392
RM437 total
includes taxes & fees
26 Oct - 27 Oct
Best Western Fort Myers Waterfront
Pool
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
3.5 star property
8.6 out of 10, Excellent, (826)
"Staff was friendly. "
United States
Jennifer
The price is RM569
RM634 total
includes taxes & fees
30 Oct - 31 Oct
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
Indoor pool
La Quinta Inn and Suites Fort Myers I-75
La Quinta Inn and Suites Fort Myers I-75
3.0 star property
6.6 out of 10, (1003)
"Pleasant and helpful staff, quiet hotel"
United States
Nadine
The price is RM316
RM352 total
includes taxes & fees
26 Oct - 27 Oct
La Quinta Inn and Suites Fort Myers I-75
Garden
Travelodge by Wyndham Fort Myers North
Travelodge by Wyndham Fort Myers North
2.0 star property
5.8 out of 10, (1001)
"I am always satisfied with my stay here. Plus the staff is always very pleasant and helpful!"
United States
Jessica
The price is RM219
RM245 total
includes taxes & fees
7 Nov - 8 Nov
Travelodge by Wyndham Fort Myers North
Interior entrance
Candlewood Suites Ft Myers I-75 by IHG
Candlewood Suites Ft Myers I-75 by IHG
2.5 star property
8.0 out of 10, Very good, (734)
"We had a great stay. The room was very nice and comfortable."
United States
Yvette
The price is RM313
RM349 total
includes taxes & fees
26 Oct - 27 Oct
Candlewood Suites Ft Myers I-75 by IHG
Laptop workspace, blackout curtains, free WiFi, bed sheets
StudioRes Fort Myers
StudioRes Fort Myers
3.0 star property
7.0 out of 10, Good, (4)
The price is RM398
RM443 total
includes taxes & fees
28 Oct - 29 Oct
StudioRes Fort Myers
Premium bedding, desk, laptop workspace, free WiFi
Riverview Inn
Riverview Inn
2.0 star property
7.6 out of 10, Good, (602)
"A nice and quiet place to stay for the weekend "
United States
Dawn
The price is RM274
RM306 total
includes taxes & fees
2 Nov - 3 Nov
Riverview Inn
Exterior
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
8.0 out of 10, Very good, (1004)
"Great place to stay and breakfast was delicious "
United States
Keishly
The price is RM369
RM411 total
includes taxes & fees
5 Nov - 6 Nov
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
View from room
Courtyard by Marriott Fort Myers Cape Coral
Courtyard by Marriott Fort Myers Cape Coral
3.0 star property
8.2 out of 10, Very good, (977)
"It was quiet, near the main highway and within walking distance to a restaurant."
United States
Elsa
The price is RM369
RM411 total
includes taxes & fees
23 Nov - 24 Nov
Courtyard by Marriott Fort Myers Cape Coral
Property amenity
MainStay Suites Fort Myers East I-75
MainStay Suites Fort Myers East I-75
2.5 star property
9.6 out of 10, Exceptional, (179)
"Great location (for what I needed to do), clean rooms, quiet area. "
United States
kevondra
The price is RM395
RM441 total
includes taxes & fees
31 Oct - 1 Nov
MainStay Suites Fort Myers East I-75
Exterior
Extended Stay America Select Suites - Fort Myers - Northeast
Extended Stay America Select Suites - Fort Myers - Northeast
2.5 star property
5.4 out of 10, (920)
"People and room"
United States
Steven
The price is RM247
RM276 total
includes taxes & fees
26 Oct - 27 Oct
Extended Stay America Select Suites - Fort Myers - Northeast
Exterior
Hyatt Place Fort Myers/at The Forum
Hyatt Place Fort Myers/at The Forum
3.0 star property
8.2 out of 10, Very good, (1000)
"More variety at breakfast "
United States
Michael
The price is RM461
RM514 total
includes taxes & fees
26 Oct - 27 Oct
Hyatt Place Fort Myers/at The Forum
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas for the activities you enjoy most.

Pelican

While visiting Pelican, you might make a stop by sights like Tarpon Point and Harbour View Gallery.

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Yacht Club

While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Veterans Foundation Headquarters are some notable places to visit nearby.

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

Mariner

While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area.

Top Matlacha Isles Hotel Reviews

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

10/10 Excellent
"Absolutely enjoyed our 1 week stay. Can’t wait to come back. Staff members were friendly and courteous "
Diane 6-night trip
Posted 1 day ago
The Lighthouse Resort Inn & Suites

Explore a world of travel with Expedia

Frequently asked questions

What is Matlacha Isles like?
Travellers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighbourhood.
How many hotels will I be able to find in the Matlacha Isles area?
When you want to put your feet up after a day of exploring the sights in Cape Coral, you can choose from 16 Expedia hotels and other accommodation options in Matlacha Isles.
If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals in Matlacha Isles.
What are the top things to see and do in Matlacha Isles?
A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens and Royal Tee Golf Club. While you're out sightseeing in Cape Coral, make sure that you visit other sights such as Little Dead Key or Big Dead Key.