A storefront with a sign reading "The Beach Club" and various clothing items displayed in the window.

Hotels near Main Street Hyannis

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Check prices for these dates

Tonight
15 Oct - 16 Oct
Tomorrow
16 Oct - 17 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Main Street Hyannis hotels

A multi-story hotel with balconies, a flat roof, and a clear sky.
An indoor swimming pool with clear water, surrounded by black chairs and tables.
A reception area with a counter, a seated area with a lamp, and framed pictures on the wall.
A hotel room with two beds, a desk, a chair, a lamp, and a nightstand with a phone and a small table.

1. Hyannis Travel Inn

Hyannis Travel Inn
0.2 km from Main Street Hyannis
United States
David J
RM404
RM463 total
includes taxes & fees
18 Oct - 19 Oct
Hyannis Travel Inn
A neatly arranged bedroom with a large bed, a bedside table, a chair, a TV mounted on the wall, and a window with blinds.
A two-story building with a covered porch and a sign for Sea Street Inn.
A dining area with black leather chairs, dark wooden tables, and white bowls.
A modern kitchen with stainless steel appliances, a central island, pendant lighting, and a textured wall.

2. Sea Street Inn

Sea Street Inn
1.5 km from Main Street Hyannis
United States
John
RM1,080
RM1,236 total
includes taxes & fees
12 Nov - 13 Nov
Sea Street Inn
A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.
A hotel with a pool area, outdoor seating, and a flag.
A marina with multiple boats docked, surrounded by residential houses and greenery.
A corridor with wooden flooring, wicker furniture, and large windows.

3. Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
0.6 km from Main Street Hyannis
United States
kathy
RM584
RM785 total
includes taxes & fees
1 Nov - 2 Nov
Anchor In Distinctive Waterfront Lodging
A poolside area with a wooden pergola, green seating, and a sign reading "LE JARDIN BLEU".
A row of white bicycles with brown seats and wicker baskets, parked in front of a white building with black railings and large windows.
A bartender pouring a drink into a gold cocktail shaker.
A modern indoor dining area with a wooden table, chairs, and a decorative wall with string lights.

4. Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
1.9 km from Main Street Hyannis
United States
Margaret
RM424
RM503 total
includes taxes & fees
1 Nov - 2 Nov
Uncommoner Hotel by Reverie Boutique Collection
A pool area with lounge chairs and flags.
A sports complex with a tennis court, parking area, and buildings with multiple floors and a sloped roof.
A modern building with a sloped roof, large windows, and a covered entrance area with seating.
A restaurant interior with tables and chairs, decorative lanterns, and potted plants.

5. The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
2.1 km from Main Street Hyannis
United States
Kim
RM526
RM602 total
includes taxes & fees
2 Nov - 3 Nov
The Cove at Yarmouth by Westgate Resorts
A covered walkway with wooden flooring, planter boxes with plants, and a white exterior wall.
A hallway with a sign reading 'ASCEND COLLECTION,' a wooden planter with plants, and a reflective floor.
An indoor swimming pool with lounge chairs, a stone wall, and a mezzanine level.
A spacious, modern restaurant with a long counter and multiple seating areas.

6. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
0.3 km from Main Street Hyannis
United States
Alexandra
RM517
RM592 total
includes taxes & fees
4 Nov - 5 Nov
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
A modern conference room with a long table, chairs, a flat-screen TV, and pendant lighting.
A reception area with a wooden reception desk, a digital kiosk, and a fireplace.
A modern reception area with a desk, chairs, a fireplace, and a decorative plant.
A hotel room with a bed, a TV, a sofa, a lamp, and a chair.

7. Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
2.3 km from Main Street Hyannis
United States
Joyce
RM517
RM592 total
includes taxes & fees
29 Oct - 30 Oct
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
An indoor swimming pool with a wooden ceiling, potted plants, and lounge chairs.
A hotel room with a bed, a chair, a table with two glasses of wine, a lamp, and a window with a view of a lake.
A beach scene with a directional signpost and beach chairs.
A beachside table with two chairs, a blue umbrella, and a white tablecloth.

8. Bayside Resort Hotel

Bayside Resort Hotel
2.3 km from Main Street Hyannis
United States
Lynn
RM314
RM407 total
includes taxes & fees
12 Nov - 13 Nov
Bayside Resort Hotel
An indoor swimming pool with a high ceiling and large windows.
View from property
A café interior with a wooden counter, a menu board, and a refrigerated display.
A hotel reception area with a digital display showing today's weather and this week's forecast.

9. Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
1.7 km from Main Street Hyannis
United States
SHREYASI
RM541
RM619 total
includes taxes & fees
15 Nov - 16 Nov
Courtyard By Marriott Cape Cod Hyannis
An outdoor patio with wicker furniture, a fire pit, and umbrellas.
A snack and drink kiosk with a 'Treats' sign, a chalkboard menu, and shelves stocked with various snacks and beverages.
A breakfast bar with waffle makers, a fruit bowl, and a coffee station.
A reception area with a sign reading "Welcome to the Patriot State" and a counter with a "Hilton" sign.

10. Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
1.7 km from Main Street Hyannis
United States
Carmen E
RM448
RM512 total
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn & Suites Cape Cod-West Yarmouth
An indoor swimming pool with a brick wall, a white table with chairs, and a large window.
A reception area with a reception desk, a clock, a fire alarm, and a sign for the courtyard resort.
A Courtyard Resort sign, a building with a brick facade, and a parking lot.
A multi-story hotel with a well-maintained lawn, outdoor seating area with chairs, and a wooden deck.

11. Courtyard Resort

Courtyard Resort
0.3 km from Main Street Hyannis
United States
Victoria R
RM572
RM654 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard Resort
An outdoor patio with round tables and chairs, a fire pit, and a covered seating area with string lights.
A DoubleTree hotel with a brick facade and a large sign.
A large indoor swimming pool with multiple lanes, surrounded by rows of chairs and a high ceiling with large windows.
A modern lounge area with a stone wall, a flat-screen TV, and comfortable seating.

12. Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
0.9 km from Main Street Hyannis
Canada
Tammie
RM479
RM548 total
includes taxes & fees
6 Nov - 7 Nov
Doubletree by Hilton Cape Cod - Hyannis
An outdoor seating area with wooden furniture and a fire pit, surrounded by trees and a gravel path.
A row of white buildings with balconies, outdoor seating, and flower beds.
A neatly made bed with white linens, a painting of a sailboat on the wall, and a door leading to a balcony.
A decorative shark sculpture with the text "Cape Sands Inn" at a beachside location.

13. Cape Sands Inn

Cape Sands Inn
1.9 km from Main Street Hyannis
United States
Jerome
RM317
RM363 total
includes taxes & fees
16 Oct - 17 Oct
Cape Sands Inn
A gym with various cardio and strength training equipment, including treadmills, elliptical machines, and weight machines.
A swimming pool with a metal ladder, surrounded by lounge chairs and umbrellas, with a building in the background.
A hotel room with a gray sofa, a television on a stand, a sliding door, a framed picture on the wall, and a lamp on a side table.
A hotel room with two beds, a desk with a computer, a chair, and a window with curtains.

14. Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
2.9 km from Main Street Hyannis
United States
Alexander
RM482
RM551 total
includes taxes & fees
6 Nov - 7 Nov
Holiday Inn Hyannis by IHG
A long dining table with chairs, a kitchen area, and a large window.
An indoor swimming pool with clear blue water, tiled walls, and a ceiling painted in blue.
A Comfort Inn hotel with a modern facade, large glass windows, and a clear sky.
A reception area with a check-in counter, blue chairs, a waiting area, and a glass door leading to a dining area.

15. Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
0.3 km from Main Street Hyannis
United States
Stephanie
RM458
RM525 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn Hyannis - Cape Cod
A two-story hotel with a curved facade, a balcony, and a sign indicating the lobby.
A waterfront hotel with a view of the marina and boats.
A modern living room with two sofas, a coffee table, and a stone wall with a fireplace.
A resort pool area with multiple lounge chairs and umbrellas, a hot tub, and a large building in the background.

16. Hyannis Harbor Hotel

Hyannis Harbor Hotel
0.6 km from Main Street Hyannis
United States
Jayne
RM559
RM703 total
includes taxes & fees
18 Oct - 19 Oct
Hyannis Harbor Hotel
A modern living room with a sofa, coffee table, and kitchen area with appliances.
A building with a covered entrance, a parking lot, and a tree with pink blossoms.
A sign for Hyannis Host Inn with a building in the background.
A hotel room with a desk, a television, a microwave, and a window with curtains.

17. Hyannis Host Inn

Hyannis Host Inn
1.6 km from Main Street Hyannis
United States
Keith
RM620
RM710 total
includes taxes & fees
16 Oct - 17 Oct
Hyannis Host Inn
A house with a brick exterior and a covered patio area.
A four-poster bed with a footboard, a bedside table with a lamp, a wooden bench, and a dresser with a mirror.
A two-story wooden house with a white picket fence, an American flag, and a sign indicating a business on the ground floor.
A two-story building with a sign for Sea Breeze Inn, including contact information and a beach view.

18. Sea Breeze Inn

Sea Breeze Inn
1.8 km from Main Street Hyannis
United States
Rita
RM323
RM369 total
includes taxes & fees
12 Nov - 13 Nov
Sea Breeze Inn
A spacious living area with a checkered floor, a wooden staircase, a sofa set, a television, and a potted plant.
A compact, modern bathroom with a wooden vanity, a mirror, a hairdryer, and a small seating area.
A flat-screen TV mounted on a wall above a fireplace with a visible fire.
A spa room with a large bathtub, a mirror, and a chandelier.

19. Hyannis Plaza Hotel

Hyannis Plaza Hotel
0.9 km from Main Street Hyannis
United States
Kali
RM429
RM531 total
includes taxes & fees
20 Oct - 21 Oct
Hyannis Plaza Hotel
A hotel room with two beige sofas, a glass coffee table, and a flat-screen TV mounted on the wall.
A hotel room with two beds, a desk with a television, a mirror, and a bathroom visible through an open door.
An indoor swimming pool with lounge chairs and a clear view of the outside.
A motel with multiple rooms, a parking lot, and picnic tables.

20. Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area

Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
1.5 km from Main Street Hyannis
United States
Katherine
RM323
RM369 total
includes taxes & fees
20 Oct - 21 Oct
Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
View all properties

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A multi-story hotel with balconies, a flat roof, and a clear sky.
Hyannis Travel Inn
9.6
Exceptional
1,012 reviews
View
A neatly arranged bedroom with a large bed, a bedside table, a chair, a TV mounted on the wall, and a window with blinds.
Sea Street Inn
9.8
Exceptional
47 reviews
View
A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.
Anchor In Distinctive Waterfront Lodging
9.4
Exceptional
1,005 reviews
View
A poolside area with a wooden pergola, green seating, and a sign reading "LE JARDIN BLEU".
Uncommoner Hotel by Reverie Boutique Collection
9.2
Wonderful
377 reviews
View
A pool area with lounge chairs and flags.
The Cove at Yarmouth by Westgate Resorts
9.2
Wonderful
269 reviews
View

Top Main Street Hyannis Hotel Reviews

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

8/10 Good
"It would be nice if there was a gym, other than that it was a great hotel. I wish the cafe and restaurant were open, or somewhere to even grab a water at night."
Marisa 1-night trip
Posted less than an hour ago
Uncommoner Hotel by Reverie Boutique Collection
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

10/10 Excellent
"Great"
Kelly 2-night trip
Posted 3 hours ago
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Bayside Resort Hotel

Bayside Resort Hotel

10/10 Excellent
"A little dated but comfortable, clean and a good choice of breakfast. Lovely area outside to the rear of the Hotel and both pool areas were very nice. Absolutely perfect if travelling with children."
judith 3-night trip
Posted 3 hours ago
Bayside Resort Hotel
Hyannis Harbor Hotel

Hyannis Harbor Hotel

8/10 Good
"No amenities"
Ray 1-night trip
Posted 22 hours ago
Hyannis Harbor Hotel
Ocean Street Inn on Hyannis Harbor

Ocean Street Inn on Hyannis Harbor

10/10 Excellent
"Loved watching people board the ferries to Nantucket and MV. Resturaunts nearby were good. Walking distance to town center."
Marian 2-night trip
Posted 22 hours ago
Ocean Street Inn on Hyannis Harbor
Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

10/10 Excellent
"Great experience from the helpful front desk to the view of the bay. Good breakfast with a personal touch by a very friendly and helpful lady . Clean room and well kept public areas The occasional ferry horn added to a real Cape Cod feel. While everything is updated and modern this property had the atmosphere of a pleasant step back in time. Highly recommend. Note: There is no elevator to the second floor."
Tom 3-night trip
Posted 1 day ago
Anchor In Distinctive Waterfront Lodging
Courtyard Resort

Courtyard Resort

8/10 Good
"Enjoyed my stay, except walls very thin and even the rain was super loud. Stay on 1st or 2nd floor, away from the main road. Terrific staff. Nice spacious room with great amenities."
Maria 2-night trip
Posted 3 days ago
Courtyard Resort
Hyannis Plaza Hotel

Hyannis Plaza Hotel

10/10 Excellent
"Property is good the bad is that doesn’t have a microwave in room and others use parking from places around and when I want to park there is no parking and I am paying for this hotel."
Franchesca 2-night trip
Posted 3 days ago
Hyannis Plaza Hotel
Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth

8/10 Good
"Clean room, friendly staff, enjoyed the daily free breakfast and the use of the fitness center."
Troy Lynn 4-night trip
Posted 4 days ago
Hampton Inn & Suites Cape Cod-West Yarmouth

Other attractions near Main Street Hyannis

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
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The Cape Cod Maritime Museum with a green sign, a white entrance, and flower planters.

Cape Cod Maritime Museum

9.0/10 (16 reviews)
You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants.
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A white church with a steeple and a sign for Saint Francis Xavier Sunday masses.

St. Francis Xavier Church

8.6/10 (58 reviews)
After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area.
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A memorial plaque with a bust of John F. Kennedy surrounded by a stone wall.

John F. Kennedy Memorial

9.0/10 (262 reviews)
Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial.
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Hyannis Armory

Learn about the local history of Hyannis with a stop at Hyannis Armory. Wander the waterfront and beautiful beaches in the area.
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Hyannis Youth & Community Center

8.2/10 (22 reviews)
You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area.
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Zion Union Heritage Museum

6.0/10 (1 review)
You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your trip to Hyannis. Make time to visit the area's shops or simply enjoy its seafood restaurants.
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Commotion Charters

6.0/10 (3 reviews)
Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area.
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Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 197 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Hyannis Harbor Hotel and Hyannis Plaza Hotel.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 197 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Centerville Historical Museum and Edward Gorey House feature captivating exhibits. Hyannis Harbor, Sandy Neck Lighthouse and West Parish Meetinghouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.