A city skyline with modern buildings, a bridge, and a park with autumn trees.

Louisville Spa Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Louisville Hotels with Spa

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

Our top choices for Louisville hotels with a spa

A modern bathroom with a walk-in shower, a freestanding bathtub, a vanity with a sink, and a mirror.

1. Market Street Inn

Market Street Inn
3.5 star property
Jeffersonville
9.8 out of 10, Exceptional, (127 reviews)
"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...
United States
Ryan
The price is RM897
RM1,014 total
includes taxes & fees
1 Nov - 2 Nov
Market Street Inn
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

2. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (514 reviews)
"Very clean / helpful and accommodating staff / excellent restaurant"
United States
Kimberly
The price is RM818
RM962 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Distil, Autograph Collection
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

3. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
4.0 star property
Old Louisville
9.6 out of 10, Exceptional, (150 reviews)
"5 STAR B&B"
United States
Casey
The price is RM739
RM858 total
includes taxes & fees
10 Nov - 11 Nov
DuPont Mansion Bed & Breakfast
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

4. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,001 reviews)
"Staff very friendly"
United States
peter
The price is RM463
RM544 total
includes taxes & fees
23 Nov - 24 Nov
Homewood Suites by Hilton Louisville Downtown, KY
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

5. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,146 reviews)
"Great stay!"
United States
Addison
The price is RM413
RM485 total
includes taxes & fees
25 Nov - 26 Nov
Tempo By Hilton Louisville Downtown Nulu
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

6. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (2,210 reviews)
"Beautiful Hotel"
United States
Kristan
The price is RM825
RM970 total
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

7. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is RM618
RM747 total
includes taxes & fees
23 Nov - 24 Nov
21c Museum Hotel Louisville
A modern hotel lobby with a large flat-screen TV, a self-service kiosk, and neatly arranged rolled towels.

8. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (169 reviews)
"Great location for whiskey row! Everyone was so and we wish we’d have had another night!! Highly recommend!"
United States
Adrienne Tremonti
The price is RM529
RM622 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

9. The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,001 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is RM632
RM744 total
includes taxes & fees
28 Nov - 29 Nov
The Grady
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

10. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (860 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is RM422
RM497 total
includes taxes & fees
29 Nov - 30 Nov
Moxy Louisville Downtown
A modern bar area with a circular bar, multiple seating options, and a large screen.

11. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,013 reviews)
"Clean and bathrooms are nice I will be staying again."
United States
Trista
The price is RM386
RM455 total
includes taxes & fees
22 Nov - 23 Nov
Cambria Hotel Louisville Downtown-Whiskey Row
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

12. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,001 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is RM461
RM542 total
includes taxes & fees
23 Nov - 24 Nov
Aloft by Marriott Louisville Downtown
A hotel lobby with a wooden reception desk, a seating area with a sofa, and a large window with potted plants.

13. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,084 reviews)
"We’ve stayed here a number of times and we love it. Right in the middle of NuLu, it’s the perfect spot."
United States
Jesse
The price is RM645
RM759 total
includes taxes & fees
1 Nov - 2 Nov
Hotel Genevieve part of JdV by Hyatt
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

14. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (730 reviews)
"Great stay"
United States
Jen
The price is RM581
RM684 total
includes taxes & fees
8 Nov - 9 Nov
AC Hotel Louisville Downtown
A covered patio with a stone wall, a glass table, and a bench.

15. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville
9.2 out of 10, Wonderful, (99 reviews)
"Amazing stay and hospitality. Will stay again"
United States
Stephen
The price is RM693
RM805 total
includes taxes & fees
2 Nov - 3 Nov
Central Park Bed & Breakfast
An outdoor seating area with wicker furniture and a fire pit.

16. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (819 reviews)
"Breakfast was very good with lots of options."
United States
Cheryl
The price is RM410
RM482 total
includes taxes & fees
30 Nov - 1 Dec
Towneplace Suites By Marriott Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

17. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,442 reviews)
"Great place to stay!!!"
United States
Shun
The price is RM552
RM650 total
includes taxes & fees
9 Nov - 10 Nov
Galt House Hotel Trademark Collection by Wyndham
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

18. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place"
United States
MILTON
The price is RM680
RM801 total
includes taxes & fees
22 Nov - 23 Nov
Louisville Marriott Downtown
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

19. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,385 reviews)
"Great room, excellent staff, exceptional breakfast, very clean."
United States
Chase
The price is RM529
RM622 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites Louisville Downtown
A modern lobby with a curved metallic structure, a seating area with a sofa and a small table, and an escalator in the background.

20. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,000 reviews)
"amazing location will definitely be back"
United States
Michael Jered
The price is RM588
RM692 total
includes taxes & fees
26 Nov - 27 Nov
Hyatt Regency Louisville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Louisville

Pool
Hot tub

Top Louisville Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"Centrally located between bars, restaurants, Bourbon row, museums, and riverboats."
Tremaine 3-night trip
Posted 7 hours ago
Galt House Hotel Trademark Collection by Wyndham
Louisville Marriott Downtown

Louisville Marriott Downtown

10/10 Excellent
"Nice, clean hotel close to all the attractions. Porch Restaurant and Bar is an excellent option for dinner if you don’t want to leave the premises."
Patrick 1-night trip
Posted 4 days ago
Louisville Marriott Downtown

Frequently asked questions

Looking for a spa hotel in Louisville?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers love the riverfront in Louisville. Make sure you pay a visit to the museums during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Louisville?
Galt House Hotel Trademark Collection by Wyndham is a top spa hotel featuring 4 restaurants, a fitness centre, a hair salon and a bar. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages and manicures/pedicures. In-room massages are also available. Other popular spa hotels in Louisville include Omni Louisville Hotel and 21c Museum Hotel Louisville.
How many spa hotels will I find in Louisville?
Among Expedia's 2317 accommodation options in Louisville, there are 4 spa hotels.
What's there to see and do in Louisville?
Experience Louisville and visit KFC Yum Center, Whiskey Row and Belle of Louisville. If you have a little extra time during your trip, you might want to check out Evan Williams Bourbon Experience and Kentucky Center for the Performing Arts.
What is a Louisville spa hotel?
Spa hotels in Louisville provide lodging and have an on-site spa which offers services such as massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.

Explore a world of travel with Expedia